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The map label for this gene is bcd [H]

Identifier: 187934827

GI number: 187934827

Start: 2066361

End: 2067500

Strand: Reverse

Name: bcd [H]

Synonym: CLL_A1988

Alternate gene names: 187934827

Gene position: 2067500-2066361 (Counterclockwise)

Preceding gene: 187933088

Following gene: 187932423

Centisome position: 54.4

GC content: 32.63

Gene sequence:

>1140_bases
ATGGACTTTACTTTAACAAAACAACAAGAAATGATTAAAGAAATGGCAAGACAATTTGCAGAAAATGAACTTAAACCAAG
GGTACTTGAAAATGATGAAAATAGTGAGTTCCCAATTGAAGCATATAAGAAATTAGGAAAATTAGGCCTTATAGGAATAC
CGTATCCAAAAGAGTATGGTGGAGCTGGTGGGGATTATTTATCTTATGTTCTAGCAGTGGAAGAAATTTCTAAAGTTGAT
GCTTCATTTGGTATATCATATTCAGTAACTACATCACTTTGCTCAGGTGGAATTATTAATGCTGCATCTGAAGAGCAAAA
GAAAAAATATCTTCCTGATGTACTTTCAGGGAAAAAACTTGGTTCTTTCGGATTAACTGAACCAAATGCAGGATCTGATG
CTGGTGGATGCATAACTACAGCAGAGAAAAAAGGAGATTATTATATATTAAATGGAAGCAAGTGTTTTATAACTAATGGC
CCGTTATCAGAAACATTTTTAGTATTTGCATTAACTGATAAGAGTAAGGGTTCAAAAGGACTATCAGCATTTATAGTTGA
AAAAGAATTTGAAGGATTTTCAATAGGTAAAATAGAAGATAAATGCGGTATAAAATCAGCACAAGTTTCAGAACTTATAT
TTGAAAATTGTAAGGTACCAGCAGAAAATTTAGTTGGTGCTGAAGGAAAAGGCTTTGGAATTGCCATGAAAGTTCTTGAT
GGTGGCAGAATCGGTGTTGCAGCTCAAGGCCTTGGAATAGCAGAAGGTGCTTTTGATATAGCGAAACAATATTTAAAAGA
TAGACAACAATTTGGAAAGCCTTTATGGAAAAATCAATATTTAGCATTTAAAATGGCAGAATTAGAGCTTGAAATTGAAA
AAGCTAAATACATTTTATATAAGGCAGCTATGGATAAACAAGAGGGAAGACAGTATTCAGTTTCAGCAGCTAAAGCTAAA
CTATCTTGTACTGATGTTGCTATGAAAGTAACAGTTGAAGCAGTTCAAATGTTGGGTGGAAATGGTTATATGAAGGAATA
TAATGTTGAAAGAATGATGAGAGATGCTAAGATTACTCAAATATATGAAGGAACAAATGAAATACAAAAACTAATTATAA
GTGGAAGCATATTTAGATAA

Upstream 100 bases:

>100_bases
CTATAATTATATTAAAATATAAAAACTCATTTAAATTGTAATTTGAAATTCAAAAAGTTGTATAGATTCAAAATAAATTA
AATACATTGGAGGAGTTAGA

Downstream 100 bases:

>100_bases
TCTTATATAAAATGATACAATTGGCGATTAGGAAAAATCATAATTTTATTTTAAATAAAAACAAAAATATATGGAAGTTT
AAACTATAGTTGTCAATTGT

Product: acyl-coa dehydrogenase, short-chain specific

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MDFTLTKQQEMIKEMARQFAENELKPRVLENDENSEFPIEAYKKLGKLGLIGIPYPKEYGGAGGDYLSYVLAVEEISKVD
ASFGISYSVTTSLCSGGIINAASEEQKKKYLPDVLSGKKLGSFGLTEPNAGSDAGGCITTAEKKGDYYILNGSKCFITNG
PLSETFLVFALTDKSKGSKGLSAFIVEKEFEGFSIGKIEDKCGIKSAQVSELIFENCKVPAENLVGAEGKGFGIAMKVLD
GGRIGVAAQGLGIAEGAFDIAKQYLKDRQQFGKPLWKNQYLAFKMAELELEIEKAKYILYKAAMDKQEGRQYSVSAAKAK
LSCTDVAMKVTVEAVQMLGGNGYMKEYNVERMMRDAKITQIYEGTNEIQKLIISGSIFR

Sequences:

>Translated_379_residues
MDFTLTKQQEMIKEMARQFAENELKPRVLENDENSEFPIEAYKKLGKLGLIGIPYPKEYGGAGGDYLSYVLAVEEISKVD
ASFGISYSVTTSLCSGGIINAASEEQKKKYLPDVLSGKKLGSFGLTEPNAGSDAGGCITTAEKKGDYYILNGSKCFITNG
PLSETFLVFALTDKSKGSKGLSAFIVEKEFEGFSIGKIEDKCGIKSAQVSELIFENCKVPAENLVGAEGKGFGIAMKVLD
GGRIGVAAQGLGIAEGAFDIAKQYLKDRQQFGKPLWKNQYLAFKMAELELEIEKAKYILYKAAMDKQEGRQYSVSAAKAK
LSCTDVAMKVTVEAVQMLGGNGYMKEYNVERMMRDAKITQIYEGTNEIQKLIISGSIFR
>Mature_379_residues
MDFTLTKQQEMIKEMARQFAENELKPRVLENDENSEFPIEAYKKLGKLGLIGIPYPKEYGGAGGDYLSYVLAVEEISKVD
ASFGISYSVTTSLCSGGIINAASEEQKKKYLPDVLSGKKLGSFGLTEPNAGSDAGGCITTAEKKGDYYILNGSKCFITNG
PLSETFLVFALTDKSKGSKGLSAFIVEKEFEGFSIGKIEDKCGIKSAQVSELIFENCKVPAENLVGAEGKGFGIAMKVLD
GGRIGVAAQGLGIAEGAFDIAKQYLKDRQQFGKPLWKNQYLAFKMAELELEIEKAKYILYKAAMDKQEGRQYSVSAAKAK
LSCTDVAMKVTVEAVQMLGGNGYMKEYNVERMMRDAKITQIYEGTNEIQKLIISGSIFR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=375, Percent_Identity=45.0666666666667, Blast_Score=342, Evalue=5e-94,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=40.9090909090909, Blast_Score=281, Evalue=5e-76,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=38.3378016085791, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=36.968085106383, Blast_Score=263, Evalue=1e-70,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=39.193083573487, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=38.2978723404255, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=38.2978723404255, Blast_Score=252, Evalue=3e-67,
Organism=Homo sapiens, GI21361497, Length=353, Percent_Identity=39.3767705382436, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=35.2, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI76496475, Length=378, Percent_Identity=36.5079365079365, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=36.5079365079365, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI4503943, Length=378, Percent_Identity=34.1269841269841, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI7669494, Length=364, Percent_Identity=33.7912087912088, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI48976061, Length=285, Percent_Identity=27.719298245614, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI211971008, Length=285, Percent_Identity=27.719298245614, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI38505218, Length=277, Percent_Identity=28.8808664259928, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=31.413612565445, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786223, Length=380, Percent_Identity=27.6315789473684, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI87082384, Length=286, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081702, Length=365, Percent_Identity=24.3835616438356, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=41.3698630136986, Blast_Score=283, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17538396, Length=373, Percent_Identity=37.8016085790885, Blast_Score=269, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=39.7877984084881, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=39.1534391534392, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=37.8082191780822, Blast_Score=258, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17570075, Length=378, Percent_Identity=38.0952380952381, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=37.17277486911, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17534353, Length=375, Percent_Identity=36.5333333333333, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI71990804, Length=273, Percent_Identity=46.5201465201465, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=36.056338028169, Blast_Score=227, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=36.90036900369, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71985192, Length=302, Percent_Identity=35.7615894039735, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=359, Percent_Identity=30.6406685236769, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17551932, Length=354, Percent_Identity=30.7909604519774, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=38.0952380952381, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17531909, Length=231, Percent_Identity=33.7662337662338, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562446, Length=254, Percent_Identity=32.2834645669291, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=269, Percent_Identity=27.8810408921933, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI86563381, Length=269, Percent_Identity=27.8810408921933, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531913, Length=171, Percent_Identity=29.2397660818713, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=43.7333333333333, Blast_Score=332, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=37.0666666666667, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=36.9973190348526, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=37.6657824933687, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24660351, Length=383, Percent_Identity=37.597911227154, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI281363737, Length=353, Percent_Identity=35.6940509915014, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19920834, Length=381, Percent_Identity=33.0708661417323, Blast_Score=202, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24652780, Length=359, Percent_Identity=22.2841225626741, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41409; Mature: 41409

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTLTKQQEMIKEMARQFAENELKPRVLENDENSEFPIEAYKKLGKLGLIGIPYPKEYG
CCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHCCCCEEECCCCHHHC
GAGGDYLSYVLAVEEISKVDASFGISYSVTTSLCSGGIINAASEEQKKKYLPDVLSGKKL
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCCCHHHHHHHCCHHHCCCCC
GSFGLTEPNAGSDAGGCITTAEKKGDYYILNGSKCFITNGPLSETFLVFALTDKSKGSKG
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCEEEEECCCCCCEEEEEEEECCCCCCCC
LSAFIVEKEFEGFSIGKIEDKCGIKSAQVSELIFENCKVPAENLVGAEGKGFGIAMKVLD
CEEEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEC
GGRIGVAAQGLGIAEGAFDIAKQYLKDRQQFGKPLWKNQYLAFKMAELELEIEKAKYILY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEHHHHHEEHH
KAAMDKQEGRQYSVSAAKAKLSCTDVAMKVTVEAVQMLGGNGYMKEYNVERMMRDAKITQ
HHHHCHHCCCEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHH
IYEGTNEIQKLIISGSIFR
HHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDFTLTKQQEMIKEMARQFAENELKPRVLENDENSEFPIEAYKKLGKLGLIGIPYPKEYG
CCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHCCCCEEECCCCHHHC
GAGGDYLSYVLAVEEISKVDASFGISYSVTTSLCSGGIINAASEEQKKKYLPDVLSGKKL
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCCCHHHHHHHCCHHHCCCCC
GSFGLTEPNAGSDAGGCITTAEKKGDYYILNGSKCFITNGPLSETFLVFALTDKSKGSKG
CCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCEEEEECCCCCCEEEEEEEECCCCCCCC
LSAFIVEKEFEGFSIGKIEDKCGIKSAQVSELIFENCKVPAENLVGAEGKGFGIAMKVLD
CEEEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEEEC
GGRIGVAAQGLGIAEGAFDIAKQYLKDRQQFGKPLWKNQYLAFKMAELELEIEKAKYILY
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEHHHHHEEHH
KAAMDKQEGRQYSVSAAKAKLSCTDVAMKVTVEAVQMLGGNGYMKEYNVERMMRDAKITQ
HHHHCHHCCCEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHCHHHHHHHHHHHH
IYEGTNEIQKLIISGSIFR
HHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]