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The map label for this gene is queC [H]

Identifier: 187934812

GI number: 187934812

Start: 2059503

End: 2060204

Strand: Reverse

Name: queC [H]

Synonym: CLL_A1980

Alternate gene names: 187934812

Gene position: 2060204-2059503 (Counterclockwise)

Preceding gene: 187934598

Following gene: 187933820

Centisome position: 54.21

GC content: 28.77

Gene sequence:

>702_bases
ATGAGAACAATATTAGTTGCAGATAAAATAATTGTATTAGATAAAGAAAAAGCAATAGTAGTATTTAGTGGTGGACAAGA
TAGCACAACTTGCTTATTTTGGGCAAAAAAGAGGTTTAGAGAAGTTATAGCAGTTTCTTTTGATTATAATCAAAAACATA
AGTTAGAATTAGAATGTGCAAGAGATATATGTAAAAAATATGATGTAGAACATCATATTTTAGATTTAAATTTATTGAAT
CAACTAGCACCTAATTCACTAACTAGACAAGATATAAGTGTTGATAAAGATGTACCTAAGGAAGGGGTTCCTAACTCATT
TGTAGATGGCAGAAATATGTTGTTTTTAACTTTTGTTGCAGTATTCGCAAAGCAAAGGGGCGTAAATACTATTATAACAG
GCGTATCTCAAAGTGATTTTAGCGGATATCCAGATTGCAGAGATGTATTTATAAAATCTTTAAATGTTACACTGAATTTA
GCTATGGATTATCAGTTTGAAATCCTTACACCATTAATGTGGATTAATAAAACAGAAACTTGGAAAATGGCTAATGATTT
AGGTGTGCTTAATATCGTTAAAGAAGAAACTTTAACTTGTTACAATGGAGTAATAGGTAATGGTTGTGGAAAATGTCCAG
CTTGTAATTTGAGAAAAAATGGATATTTAGAATTTAAAAAAGAATATTTAAACATTTACTAG

Upstream 100 bases:

>100_bases
AATAGAGTGAGCTATATCAAAATGATTAAAGTTAATTATTTTGATATAGTTTTTATCTGTGTTAATCAAAGAAAAAACGG
TTATTGTTATTGCCCATAGA

Downstream 100 bases:

>100_bases
TTTTAAACTATACTAATATAGAGAAAAATATTTGCGAGGTAGAGATGTCTATATATTTTGATGTCAAAACTATTAGAGAA
CTTATAGGAGATAATTATAG

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRTILVADKIIVLDKEKAIVVFSGGQDSTTCLFWAKKRFREVIAVSFDYNQKHKLELECARDICKKYDVEHHILDLNLLN
QLAPNSLTRQDISVDKDVPKEGVPNSFVDGRNMLFLTFVAVFAKQRGVNTIITGVSQSDFSGYPDCRDVFIKSLNVTLNL
AMDYQFEILTPLMWINKTETWKMANDLGVLNIVKEETLTCYNGVIGNGCGKCPACNLRKNGYLEFKKEYLNIY

Sequences:

>Translated_233_residues
MRTILVADKIIVLDKEKAIVVFSGGQDSTTCLFWAKKRFREVIAVSFDYNQKHKLELECARDICKKYDVEHHILDLNLLN
QLAPNSLTRQDISVDKDVPKEGVPNSFVDGRNMLFLTFVAVFAKQRGVNTIITGVSQSDFSGYPDCRDVFIKSLNVTLNL
AMDYQFEILTPLMWINKTETWKMANDLGVLNIVKEETLTCYNGVIGNGCGKCPACNLRKNGYLEFKKEYLNIY
>Mature_233_residues
MRTILVADKIIVLDKEKAIVVFSGGQDSTTCLFWAKKRFREVIAVSFDYNQKHKLELECARDICKKYDVEHHILDLNLLN
QLAPNSLTRQDISVDKDVPKEGVPNSFVDGRNMLFLTFVAVFAKQRGVNTIITGVSQSDFSGYPDCRDVFIKSLNVTLNL
AMDYQFEILTPLMWINKTETWKMANDLGVLNIVKEETLTCYNGVIGNGCGKCPACNLRKNGYLEFKKEYLNIY

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=210, Percent_Identity=54.7619047619048, Blast_Score=238, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 26538; Mature: 26538

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTILVADKIIVLDKEKAIVVFSGGQDSTTCLFWAKKRFREVIAVSFDYNQKHKLELECA
CCEEEEECEEEEEECCCEEEEEECCCCCCEEEHHHHHHHHHHEEEEECCCCCCEEEHHHH
RDICKKYDVEHHILDLNLLNQLAPNSLTRQDISVDKDVPKEGVPNSFVDGRNMLFLTFVA
HHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VFAKQRGVNTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYQFEILTPLMWINKTET
HHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCHHHHHHHHHCCCCCC
WKMANDLGVLNIVKEETLTCYNGVIGNGCGKCPACNLRKNGYLEFKKEYLNIY
EEHHCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCC
>Mature Secondary Structure
MRTILVADKIIVLDKEKAIVVFSGGQDSTTCLFWAKKRFREVIAVSFDYNQKHKLELECA
CCEEEEECEEEEEECCCEEEEEECCCCCCEEEHHHHHHHHHHEEEEECCCCCCEEEHHHH
RDICKKYDVEHHILDLNLLNQLAPNSLTRQDISVDKDVPKEGVPNSFVDGRNMLFLTFVA
HHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VFAKQRGVNTIITGVSQSDFSGYPDCRDVFIKSLNVTLNLAMDYQFEILTPLMWINKTET
HHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHCCEEEEEEEECCHHHHHHHHHCCCCCC
WKMANDLGVLNIVKEETLTCYNGVIGNGCGKCPACNLRKNGYLEFKKEYLNIY
EEHHCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA