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The map label for this gene is pfp [H]

Identifier: 187934512

GI number: 187934512

Start: 781461

End: 782678

Strand: Reverse

Name: pfp [H]

Synonym: CLL_A0769

Alternate gene names: 187934512

Gene position: 782678-781461 (Counterclockwise)

Preceding gene: 187934961

Following gene: 187932940

Centisome position: 20.6

GC content: 28.98

Gene sequence:

>1218_bases
ATGTCTAATTGTATTATTGCACAATCTGGTGGTCCAACTTCTGTTATTAATTCTAGTGTAGTAGGATTAATACATGCTAA
TAAGTCACTTAAAGTTTTTAATAAAGTCTATGGTGGTTTAAATGGTATTGAAGGAATTTTGAATAAGAATATAATTGATC
TTACCCTAATTAATGATGATGAGTTACAAACTTTTAGATACACACCATCTTCTGGGTTAGGATCTTGTAGATATAAATTA
CAAAATCCCAATAATTCTTGTGATGAATATGAAAAACTAGTAGAAATATTAAAAGAATATGATATAACTTCATTTTTTTA
TATAGGTGGAAATGATTCTATGGATACAATTGCTAAACTTTCTGCTTATTCTAAAAAAAATAATATTGATATAAACTTTA
TTGGTATTCCTAAAACAATTGATAATGATTTAATGTTTACTGATCATACCCCTGGTTTTGGTAGTGCTGCAAAATTCATT
ACAACATCAGTATTAGAAACTTATCTTGACTCTTCTGTATATATTAACAATGGTATTTTTATATTGGAAACAATGGGCCG
AGATACAGGTTGGCTAGCAGCCTCAGCTTGCATAGCTAAAATAGATGACAAACCTGTTGCTGATTTTATTTACTTGCCCG
AAACGGCTTTTGATAAATATCAATTTATCAATGATGTTAGACAAAAGTTTAAAGAACAAAACAAAGTATATATTGTTGTA
TCTGAAGGCATTAAAGATGAAACTGGTAAATTTATATCTGAGTTTCAATGTGTTTCTAATGATAATTTTGGACATGCTCA
ATTAGGTGGTGTTAGCCAGTATCTAAGAAATTTACTTCTCGATGCCGGTATAACTAAAAGAGTAAAAGCTTTAGAACTTG
GAATTTTACAGCGTTGTGCCATGCACTTTGCATCTGATTCTGATTTAAATGAAGCTTATGATGTTGGTTATGTAGCTTTA
CAAAGTGCATTAAATAATGAAAGTGGTAAAATGGTTGCTATAAAACGTGCTGATTCTAAAGACTATAAATCATCTTACTT
CTTAGTAGATGCTGATAAAGTAGCTAATAATGTTAGGTACTTCCCTTCTGAATGGATTAATGAAGATGGAAACTTCTTAA
AAGAAGAGGCTTGTGAATACTTTTTACCATTAGTAAAAAATATTCCTAATTTAAAATTAGAAAATAATTTACCACAATAT
AAAGTTTTTAACGTCTAA

Upstream 100 bases:

>100_bases
ATTTAATGTACTTTTTGTTGTATATTATTAAATAGAGTATTATTAATAAGTAAATAGTATATCACATTTATACTATTTTG
TTTTAAAAAGGAGCGTTTTT

Downstream 100 bases:

>100_bases
TTATGTTTAACTGAGTAAAAGAGTTATTAAACTAAAACTAATAACTCTTTTACTATAAAAATCTAATATCACCAAGATTT
CATATCATCTAAAGAATGAA

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSNCIIAQSGGPTSVINSSVVGLIHANKSLKVFNKVYGGLNGIEGILNKNIIDLTLINDDELQTFRYTPSSGLGSCRYKL
QNPNNSCDEYEKLVEILKEYDITSFFYIGGNDSMDTIAKLSAYSKKNNIDINFIGIPKTIDNDLMFTDHTPGFGSAAKFI
TTSVLETYLDSSVYINNGIFILETMGRDTGWLAASACIAKIDDKPVADFIYLPETAFDKYQFINDVRQKFKEQNKVYIVV
SEGIKDETGKFISEFQCVSNDNFGHAQLGGVSQYLRNLLLDAGITKRVKALELGILQRCAMHFASDSDLNEAYDVGYVAL
QSALNNESGKMVAIKRADSKDYKSSYFLVDADKVANNVRYFPSEWINEDGNFLKEEACEYFLPLVKNIPNLKLENNLPQY
KVFNV

Sequences:

>Translated_405_residues
MSNCIIAQSGGPTSVINSSVVGLIHANKSLKVFNKVYGGLNGIEGILNKNIIDLTLINDDELQTFRYTPSSGLGSCRYKL
QNPNNSCDEYEKLVEILKEYDITSFFYIGGNDSMDTIAKLSAYSKKNNIDINFIGIPKTIDNDLMFTDHTPGFGSAAKFI
TTSVLETYLDSSVYINNGIFILETMGRDTGWLAASACIAKIDDKPVADFIYLPETAFDKYQFINDVRQKFKEQNKVYIVV
SEGIKDETGKFISEFQCVSNDNFGHAQLGGVSQYLRNLLLDAGITKRVKALELGILQRCAMHFASDSDLNEAYDVGYVAL
QSALNNESGKMVAIKRADSKDYKSSYFLVDADKVANNVRYFPSEWINEDGNFLKEEACEYFLPLVKNIPNLKLENNLPQY
KVFNV
>Mature_404_residues
SNCIIAQSGGPTSVINSSVVGLIHANKSLKVFNKVYGGLNGIEGILNKNIIDLTLINDDELQTFRYTPSSGLGSCRYKLQ
NPNNSCDEYEKLVEILKEYDITSFFYIGGNDSMDTIAKLSAYSKKNNIDINFIGIPKTIDNDLMFTDHTPGFGSAAKFIT
TSVLETYLDSSVYINNGIFILETMGRDTGWLAASACIAKIDDKPVADFIYLPETAFDKYQFINDVRQKFKEQNKVYIVVS
EGIKDETGKFISEFQCVSNDNFGHAQLGGVSQYLRNLLLDAGITKRVKALELGILQRCAMHFASDSDLNEAYDVGYVALQ
SALNNESGKMVAIKRADSKDYKSSYFLVDADKVANNVRYFPSEWINEDGNFLKEEACEYFLPLVKNIPNLKLENNLPQYK
VFNV

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=373, Percent_Identity=24.6648793565684, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 45242; Mature: 45110

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNCIIAQSGGPTSVINSSVVGLIHANKSLKVFNKVYGGLNGIEGILNKNIIDLTLINDD
CCCEEEECCCCCHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHCCCEEEEEEECCC
ELQTFRYTPSSGLGSCRYKLQNPNNSCDEYEKLVEILKEYDITSFFYIGGNDSMDTIAKL
CCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
SAYSKKNNIDINFIGIPKTIDNDLMFTDHTPGFGSAAKFITTSVLETYLDSSVYINNGIF
HHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEE
ILETMGRDTGWLAASACIAKIDDKPVADFIYLPETAFDKYQFINDVRQKFKEQNKVYIVV
EEEECCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEE
SEGIKDETGKFISEFQCVSNDNFGHAQLGGVSQYLRNLLLDAGITKRVKALELGILQRCA
ECCCCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MHFASDSDLNEAYDVGYVALQSALNNESGKMVAIKRADSKDYKSSYFLVDADKVANNVRY
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEHHHHHCCCCC
FPSEWINEDGNFLKEEACEYFLPLVKNIPNLKLENNLPQYKVFNV
CCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEECC
>Mature Secondary Structure 
SNCIIAQSGGPTSVINSSVVGLIHANKSLKVFNKVYGGLNGIEGILNKNIIDLTLINDD
CCEEEECCCCCHHHHCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHCCCEEEEEEECCC
ELQTFRYTPSSGLGSCRYKLQNPNNSCDEYEKLVEILKEYDITSFFYIGGNDSMDTIAKL
CCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
SAYSKKNNIDINFIGIPKTIDNDLMFTDHTPGFGSAAKFITTSVLETYLDSSVYINNGIF
HHHCCCCCCEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEE
ILETMGRDTGWLAASACIAKIDDKPVADFIYLPETAFDKYQFINDVRQKFKEQNKVYIVV
EEEECCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEE
SEGIKDETGKFISEFQCVSNDNFGHAQLGGVSQYLRNLLLDAGITKRVKALELGILQRCA
ECCCCCHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
MHFASDSDLNEAYDVGYVALQSALNNESGKMVAIKRADSKDYKSSYFLVDADKVANNVRY
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEHHHHHCCCCC
FPSEWINEDGNFLKEEACEYFLPLVKNIPNLKLENNLPQYKVFNV
CCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550409 [H]