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The map label for this gene is nuoE [H]

Identifier: 187934365

GI number: 187934365

Start: 2380507

End: 2380998

Strand: Reverse

Name: nuoE [H]

Synonym: CLL_A2309

Alternate gene names: 187934365

Gene position: 2380998-2380507 (Counterclockwise)

Preceding gene: 187935366

Following gene: 187932967

Centisome position: 62.65

GC content: 31.71

Gene sequence:

>492_bases
ATGATGTTAAAAGAAGAGGAAATGAAAGAATTAGATAACATTTTAGCTTCTCATAATTATCAAAAGTCGTCAGTTATTGC
TGTAATGCAAGAAGTTCAAAAACAATATCGTTATTTACCAAAGGAAGCACTATGTTATATTGCAAAACATTTAAAAATAA
GTGAAGCCAAAATATATGGCGTTGCAACTTTCTATGAAAATTTTTCATTACAACCTAAAGGAAAATATGTAATAAAGATT
TGTGATGGAACTGCATGTCATGTAAGGGGTTCTATACCTATATTGGAGGAATTTAGGAAGCTGTTAGGTCTTTCAGAAAG
TAAGGTTACAACAGATGATATGATTTTTACAGTTGAAACTGTATCTTGTTTAGGCGCGTGTGGATTAGCACCTGTCTGTA
CTGTAAACGATGTAGTATATCCTAGTATGACTCAGCAAAAGGCTAGAGACATAATAAAAAAGTTAAAGGAGGAAGCATCT
AATGAGAATTAA

Upstream 100 bases:

>100_bases
CGCTAAAGGTGATTAAATATATTGCAAATGTGTACAAGCACAGTATATATAATCATTTTTGATTTTTCATAATATTTAAC
AAAATGTGGGGGTGGGACAA

Downstream 100 bases:

>100_bases
TACTAGAGAAGAATTAAATTCTTCAATAAAAAAATGTAAGTTAGCTTTAGGCAAGCAATCTAAACAAATATTAATTTGTG
GTGGAACTGGTTGTGTAGCT

Product: Fe-hydrogenase gamma subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MMLKEEEMKELDNILASHNYQKSSVIAVMQEVQKQYRYLPKEALCYIAKHLKISEAKIYGVATFYENFSLQPKGKYVIKI
CDGTACHVRGSIPILEEFRKLLGLSESKVTTDDMIFTVETVSCLGACGLAPVCTVNDVVYPSMTQQKARDIIKKLKEEAS
NEN

Sequences:

>Translated_163_residues
MMLKEEEMKELDNILASHNYQKSSVIAVMQEVQKQYRYLPKEALCYIAKHLKISEAKIYGVATFYENFSLQPKGKYVIKI
CDGTACHVRGSIPILEEFRKLLGLSESKVTTDDMIFTVETVSCLGACGLAPVCTVNDVVYPSMTQQKARDIIKKLKEEAS
NEN
>Mature_163_residues
MMLKEEEMKELDNILASHNYQKSSVIAVMQEVQKQYRYLPKEALCYIAKHLKISEAKIYGVATFYENFSLQPKGKYVIKI
CDGTACHVRGSIPILEEFRKLLGLSESKVTTDDMIFTVETVSCLGACGLAPVCTVNDVVYPSMTQQKARDIIKKLKEEAS
NEN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=153, Percent_Identity=35.9477124183007, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI1788621, Length=141, Percent_Identity=31.2056737588652, Blast_Score=80, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17561328, Length=152, Percent_Identity=34.8684210526316, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI18859877, Length=155, Percent_Identity=37.4193548387097, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21355353, Length=137, Percent_Identity=33.5766423357664, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18407; Mature: 18407

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLKEEEMKELDNILASHNYQKSSVIAVMQEVQKQYRYLPKEALCYIAKHLKISEAKIYG
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHEE
VATFYENFSLQPKGKYVIKICDGTACHVRGSIPILEEFRKLLGLSESKVTTDDMIFTVET
HHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHEEHHHH
VSCLGACGLAPVCTVNDVVYPSMTQQKARDIIKKLKEEASNEN
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMLKEEEMKELDNILASHNYQKSSVIAVMQEVQKQYRYLPKEALCYIAKHLKISEAKIYG
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHEE
VATFYENFSLQPKGKYVIKICDGTACHVRGSIPILEEFRKLLGLSESKVTTDDMIFTVET
HHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHEEHHHH
VSCLGACGLAPVCTVNDVVYPSMTQQKARDIIKKLKEEASNEN
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]