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The map label for this gene is 187934094

Identifier: 187934094

GI number: 187934094

Start: 3187174

End: 3188424

Strand: Reverse

Name: 187934094

Synonym: CLL_A3081

Alternate gene names: NA

Gene position: 3188424-3187174 (Counterclockwise)

Preceding gene: 187932558

Following gene: 187935069

Centisome position: 83.9

GC content: 28.3

Gene sequence:

>1251_bases
ATGAAGAAATTATCAGTATTTTTATATACAAATATTTTATTTAAAAATATTTACGATGAATTTGGGGATGTTTTAGGAGA
ATTAAGAGATGTTTATGTAACAACAGAAGAGGGATATCCAAGAGTTATAGGCTACAAACTTAGGAAGGACGGCATTACAT
TTCATTATGAGTTTAGATATATAGAGTTTTTAGATGATAATGGAAATGTAAAGATAAGAACAAGAGGAAGCAAAGAAATA
CTTCCAATGACTTATACTTATCTTCTTTCAAAAAATTTATTAGACAAAAAAATAGTAGATATAAATGGAAAGCAAGTAGT
ACGTGTTAATGATTTGAGAATTGCTGAAATAGCAGGGGAATACAGAGTTGTAGCAGTTGAGACAGGACCACTTGCACGAT
ATAGAAGGTTGAATGTTGCAGGAATTGCTAAATGTGTATATAAGCTTTTAGGTAAAGATTATGAAGATAAAGTTTTAATG
TGGGAAGATGTTGAATCATTAGAAATGGTTGATAACAATTTAAAGTTGGTAGTACCATATCAAAAATTATCAACACTACA
TCCAGCTGACCTTGCAGATATACTAGAAGATTTAGATGCAAGATCTAGAAAACAGATATTTGAATCATTAGATGAGGATT
TAGCAGCAGACACATTGGAAGAAATAGATCCTGAATATAAGGGTAGTATAATTAAGGATTTATCAGAAACTAAAGCAGCT
GAAGTTCTAGAAAACATGGCTAATGATGAAATAGCTGATCTTTTAGATGATTTAGATGAAGAAGAAAGAGAAAAAATATT
AATAAATTTAGAAAAAGAAGATGCTAAGGAAGTTAAAGAATTACTTGAATATGAAGATGAAACTGTTGGTAGTATTATGA
GTAAAGAGTTTATATCATTAAACTTAGATATAACAATTTCTGATGCATTAGATATACTTAAAGAAATGCAACCTGATGAA
GAGGTTATGTACTATATATATATAACAAATGAAGAAGATAAGATTGAAGGTATGATTTCATTAAGAGATTTAATAATAAA
TGATAGTAGTAAAAAAATAAAAGATATAATGGATGAAACTGTTTCTCGTGTAAAACATGATGATAAAATAAATGAAGCAA
TAGAAGCAGCAGCTAAATATGATTTGGTTACAGTACCAGTAGTAGATGATGAGGATAAATTGGTTGGAACAGTTATAATC
CATGATTTAATAGATGAATTTTTATTTCCTCTTTGGAAGAAGAAAAATTAA

Upstream 100 bases:

>100_bases
TTAATAATTTTAAATTACAATTTAATATATTTAGGAAGAGCTATTCATCTATTTAAATATAATGAAAGTTCTTTCTGAAA
ACATATAGGAGGAATCTTTC

Downstream 100 bases:

>100_bases
ATAATTTTTTAAAATTATATTGACTTTTTTTTGAAATAACATATAATGAAAATATAAAGCATATCAATTTACTCAGAATT
AAAAACTGTGAAAAAGTAAA

Product: CBS domain/MgtE intracellular domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MKKLSVFLYTNILFKNIYDEFGDVLGELRDVYVTTEEGYPRVIGYKLRKDGITFHYEFRYIEFLDDNGNVKIRTRGSKEI
LPMTYTYLLSKNLLDKKIVDINGKQVVRVNDLRIAEIAGEYRVVAVETGPLARYRRLNVAGIAKCVYKLLGKDYEDKVLM
WEDVESLEMVDNNLKLVVPYQKLSTLHPADLADILEDLDARSRKQIFESLDEDLAADTLEEIDPEYKGSIIKDLSETKAA
EVLENMANDEIADLLDDLDEEEREKILINLEKEDAKEVKELLEYEDETVGSIMSKEFISLNLDITISDALDILKEMQPDE
EVMYYIYITNEEDKIEGMISLRDLIINDSSKKIKDIMDETVSRVKHDDKINEAIEAAAKYDLVTVPVVDDEDKLVGTVII
HDLIDEFLFPLWKKKN

Sequences:

>Translated_416_residues
MKKLSVFLYTNILFKNIYDEFGDVLGELRDVYVTTEEGYPRVIGYKLRKDGITFHYEFRYIEFLDDNGNVKIRTRGSKEI
LPMTYTYLLSKNLLDKKIVDINGKQVVRVNDLRIAEIAGEYRVVAVETGPLARYRRLNVAGIAKCVYKLLGKDYEDKVLM
WEDVESLEMVDNNLKLVVPYQKLSTLHPADLADILEDLDARSRKQIFESLDEDLAADTLEEIDPEYKGSIIKDLSETKAA
EVLENMANDEIADLLDDLDEEEREKILINLEKEDAKEVKELLEYEDETVGSIMSKEFISLNLDITISDALDILKEMQPDE
EVMYYIYITNEEDKIEGMISLRDLIINDSSKKIKDIMDETVSRVKHDDKINEAIEAAAKYDLVTVPVVDDEDKLVGTVII
HDLIDEFLFPLWKKKN
>Mature_416_residues
MKKLSVFLYTNILFKNIYDEFGDVLGELRDVYVTTEEGYPRVIGYKLRKDGITFHYEFRYIEFLDDNGNVKIRTRGSKEI
LPMTYTYLLSKNLLDKKIVDINGKQVVRVNDLRIAEIAGEYRVVAVETGPLARYRRLNVAGIAKCVYKLLGKDYEDKVLM
WEDVESLEMVDNNLKLVVPYQKLSTLHPADLADILEDLDARSRKQIFESLDEDLAADTLEEIDPEYKGSIIKDLSETKAA
EVLENMANDEIADLLDDLDEEEREKILINLEKEDAKEVKELLEYEDETVGSIMSKEFISLNLDITISDALDILKEMQPDE
EVMYYIYITNEEDKIEGMISLRDLIINDSSKKIKDIMDETVSRVKHDDKINEAIEAAAKYDLVTVPVVDDEDKLVGTVII
HDLIDEFLFPLWKKKN

Specific function: Acts as a magnesium transporter [H]

COG id: COG2239

COG function: function code P; Mg/Co/Ni transporter MgtE (contains CBS domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR006668
- InterPro:   IPR006667
- InterPro:   IPR006669 [H]

Pfam domain/function: PF00571 CBS; PF01769 MgtE; PF03448 MgtE_N [H]

EC number: NA

Molecular weight: Translated: 48040; Mature: 48040

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSVFLYTNILFKNIYDEFGDVLGELRDVYVTTEEGYPRVIGYKLRKDGITFHYEFRY
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEECCCEEEEEEEEE
IEFLDDNGNVKIRTRGSKEILPMTYTYLLSKNLLDKKIVDINGKQVVRVNDLRIAEIAGE
EEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECEEEEEECCC
YRVVAVETGPLARYRRLNVAGIAKCVYKLLGKDYEDKVLMWEDVESLEMVDNNLKLVVPY
EEEEEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCEEEEEH
QKLSTLHPADLADILEDLDARSRKQIFESLDEDLAADTLEEIDPEYKGSIIKDLSETKAA
HHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHH
EVLENMANDEIADLLDDLDEEEREKILINLEKEDAKEVKELLEYEDETVGSIMSKEFISL
HHHHHHCCHHHHHHHHCCCHHCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHEEE
NLDITISDALDILKEMQPDEEVMYYIYITNEEDKIEGMISLRDLIINDSSKKIKDIMDET
EEEEEEHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VSRVKHDDKINEAIEAAAKYDLVTVPVVDDEDKLVGTVIIHDLIDEFLFPLWKKKN
HHHHHCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKLSVFLYTNILFKNIYDEFGDVLGELRDVYVTTEEGYPRVIGYKLRKDGITFHYEFRY
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEECCCEEEEEEEEE
IEFLDDNGNVKIRTRGSKEILPMTYTYLLSKNLLDKKIVDINGKQVVRVNDLRIAEIAGE
EEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEECEEEEEECCC
YRVVAVETGPLARYRRLNVAGIAKCVYKLLGKDYEDKVLMWEDVESLEMVDNNLKLVVPY
EEEEEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCEEEEEH
QKLSTLHPADLADILEDLDARSRKQIFESLDEDLAADTLEEIDPEYKGSIIKDLSETKAA
HHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHH
EVLENMANDEIADLLDDLDEEEREKILINLEKEDAKEVKELLEYEDETVGSIMSKEFISL
HHHHHHCCHHHHHHHHCCCHHCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHEEE
NLDITISDALDILKEMQPDEEVMYYIYITNEEDKIEGMISLRDLIINDSSKKIKDIMDET
EEEEEEHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VSRVKHDDKINEAIEAAAKYDLVTVPVVDDEDKLVGTVIIHDLIDEFLFPLWKKKN
HHHHHCHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA