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The map label for this gene is ptsG [H]

Identifier: 187933951

GI number: 187933951

Start: 3612496

End: 3614148

Strand: Reverse

Name: ptsG [H]

Synonym: CLL_A3423

Alternate gene names: 187933951

Gene position: 3614148-3612496 (Counterclockwise)

Preceding gene: 187932982

Following gene: 187934757

Centisome position: 95.1

GC content: 33.27

Gene sequence:

>1653_bases
ATGCTTCAATATTTACAAAGAATAGGTAAAGCTATAATGCTACCAATCGCAGCTTTACCAATCGCAGGTATATTATTAGG
AGTTGGTGGAGCTTTACTTGGAATTGCAGGATTAAATAATCCACCATCAGTTTATGAACCACTTATAGCATTTGTTAGTA
TTCCAGCAGTTACTGCTATATTAACAGTAATGAAAAATATAGGTGATATTATTTTTGGAAACTTACCAATACTATTTGCA
GTAGGTGTTGCAGTAGGTCTTGCTAAAAAAGACAAAGGTACAGCAGCATTAGCATCAGTATTTGGATTTATCGTAATGAA
TCAAGTTATTTCAACATTACTAGCTTTAGGAGTTACTCAATTAGGGGTTCTTACTCCAGACAGTTTTGGTGAATATGGTA
CATATATTACAACTAATTTAGGTATATTCACATTAAATATGTCAGTATTTGGTGGTATTATTACAGGTATTATTACAGCA
ATATTACATGATAGATTCCATGAAATCCAATTACCACAAATATTAGGATTTTTCTCAGGATCAAGATTTGTTCCTATAAT
AACAGCAGTTACTATGGCAATTGTAGGAGCTATATTAGCATTTTTATGGCCAGTAGTTCAAGATGGTATTGGAGTTATAG
CTAACTTAGTTAGAAATGCAGGATTTATAGGAAGCTTTTTCTATGGAGTCATTGAAAGAGCATTAATTCCATTTGGATTA
CATCATGTATTCTATACTCCATTCTGGTTTGGATCATTTGTTGATGGTCAAATATTAGTTAATGGAACTTGGCAAACAGT
AGCAGGTGCAAACACTGCATACTTTGCTCAATTATCAAGCATGACTGATTTAGTGGGTGCATCAGCAGATACTATGTCAA
CAATAGTTAGTGGAACTACAAGATTCATGGCAGGTAAATTCCCATTCATGATGTTTGGATTACCAGCAGCAGCTTTTGCT
ATGTACAGAGCAGCAGCTCCAAGCAAGAGAAAAACAGTTGGATCATTATTATTAGCAGCAGCGATTACTTCATTATTAAC
AGGTATTACTGAACCGTTAGAATTTACATTCATATTCGTTGCTCCAGTATTATATGGAGTACACTGTATATTAGCAGGTT
TATCATTCATGTTAATGGATATATTCAATGTATTCATAGGAATGACATTCTCAGGTGGATTAATTGACTTTAGTTTATTT
GGATTACTTCCAGCAGGAGCAGGAGTTCCAACCAAATGGTTTATGGTACTATTAATAGGAGTAGTTTATGCAGTAGTTTA
TTATTTCTTATTCTACTTCATGATTACCAAGCTTAATTTAAAAACTCCTGGTAGAGATGAAAATGAAGAAGAAACTAAAT
TATACACTAAAGCTGACTACCAAGGTAAAAAGGGAAACGCTAAAAGTGAAATAGTTGAAAAAGCACCAGCTGTATTATCA
GCATTAGGTGGAGAAGAAAATATCGTAAGTGTTGATGCTTGTATAACAAGACTTAGAGTTGAAGTTAAGGACAAAGCTAA
AGTTGATAAAGATGAATTAAAAACTTTAGGTGCAGCAGGTGTTATGGAAGTTGGTAATGGAATTCAAGCTATATTTGGAG
CTAAAGCCGATGGATATAAAAATGCTATCAATGATATATTAGGTATTAGTTAA

Upstream 100 bases:

>100_bases
AGTCTTTTTTATTTGCATAATTTTTGGCTGGCCGGCTAAAAATAGCAACATATACTTACATAATATTTTATTTTATTTAA
TAACTTTAGGAGGAATTATT

Downstream 100 bases:

>100_bases
TAATTAGTTTATACAATTAGTTTATAAAAATTTTGCCCTAGCAGATAAATATTGAGTTATCTACTAGGGCATTTAAATTT
TGTGAATATTTTTTTAAAAT

Product: PTS system, glucose-like IIB component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MLQYLQRIGKAIMLPIAALPIAGILLGVGGALLGIAGLNNPPSVYEPLIAFVSIPAVTAILTVMKNIGDIIFGNLPILFA
VGVAVGLAKKDKGTAALASVFGFIVMNQVISTLLALGVTQLGVLTPDSFGEYGTYITTNLGIFTLNMSVFGGIITGIITA
ILHDRFHEIQLPQILGFFSGSRFVPIITAVTMAIVGAILAFLWPVVQDGIGVIANLVRNAGFIGSFFYGVIERALIPFGL
HHVFYTPFWFGSFVDGQILVNGTWQTVAGANTAYFAQLSSMTDLVGASADTMSTIVSGTTRFMAGKFPFMMFGLPAAAFA
MYRAAAPSKRKTVGSLLLAAAITSLLTGITEPLEFTFIFVAPVLYGVHCILAGLSFMLMDIFNVFIGMTFSGGLIDFSLF
GLLPAGAGVPTKWFMVLLIGVVYAVVYYFLFYFMITKLNLKTPGRDENEEETKLYTKADYQGKKGNAKSEIVEKAPAVLS
ALGGEENIVSVDACITRLRVEVKDKAKVDKDELKTLGAAGVMEVGNGIQAIFGAKADGYKNAINDILGIS

Sequences:

>Translated_550_residues
MLQYLQRIGKAIMLPIAALPIAGILLGVGGALLGIAGLNNPPSVYEPLIAFVSIPAVTAILTVMKNIGDIIFGNLPILFA
VGVAVGLAKKDKGTAALASVFGFIVMNQVISTLLALGVTQLGVLTPDSFGEYGTYITTNLGIFTLNMSVFGGIITGIITA
ILHDRFHEIQLPQILGFFSGSRFVPIITAVTMAIVGAILAFLWPVVQDGIGVIANLVRNAGFIGSFFYGVIERALIPFGL
HHVFYTPFWFGSFVDGQILVNGTWQTVAGANTAYFAQLSSMTDLVGASADTMSTIVSGTTRFMAGKFPFMMFGLPAAAFA
MYRAAAPSKRKTVGSLLLAAAITSLLTGITEPLEFTFIFVAPVLYGVHCILAGLSFMLMDIFNVFIGMTFSGGLIDFSLF
GLLPAGAGVPTKWFMVLLIGVVYAVVYYFLFYFMITKLNLKTPGRDENEEETKLYTKADYQGKKGNAKSEIVEKAPAVLS
ALGGEENIVSVDACITRLRVEVKDKAKVDKDELKTLGAAGVMEVGNGIQAIFGAKADGYKNAINDILGIS
>Mature_550_residues
MLQYLQRIGKAIMLPIAALPIAGILLGVGGALLGIAGLNNPPSVYEPLIAFVSIPAVTAILTVMKNIGDIIFGNLPILFA
VGVAVGLAKKDKGTAALASVFGFIVMNQVISTLLALGVTQLGVLTPDSFGEYGTYITTNLGIFTLNMSVFGGIITGIITA
ILHDRFHEIQLPQILGFFSGSRFVPIITAVTMAIVGAILAFLWPVVQDGIGVIANLVRNAGFIGSFFYGVIERALIPFGL
HHVFYTPFWFGSFVDGQILVNGTWQTVAGANTAYFAQLSSMTDLVGASADTMSTIVSGTTRFMAGKFPFMMFGLPAAAFA
MYRAAAPSKRKTVGSLLLAAAITSLLTGITEPLEFTFIFVAPVLYGVHCILAGLSFMLMDIFNVFIGMTFSGGLIDFSLF
GLLPAGAGVPTKWFMVLLIGVVYAVVYYFLFYFMITKLNLKTPGRDENEEETKLYTKADYQGKKGNAKSEIVEKAPAVLS
ALGGEENIVSVDACITRLRVEVKDKAKVDKDELKTLGAAGVMEVGNGIQAIFGAKADGYKNAINDILGIS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=552, Percent_Identity=39.1304347826087, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1787343, Length=546, Percent_Identity=38.8278388278388, Blast_Score=344, Evalue=7e-96,
Organism=Escherichia coli, GI1786894, Length=548, Percent_Identity=35.5839416058394, Blast_Score=274, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 58488; Mature: 58488

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCC
>Mature Secondary Structure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HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]