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The map label for this gene is clpP [H]

Identifier: 187933949

GI number: 187933949

Start: 2344043

End: 2344786

Strand: Reverse

Name: clpP [H]

Synonym: CLL_A2258

Alternate gene names: 187933949

Gene position: 2344786-2344043 (Counterclockwise)

Preceding gene: 187933457

Following gene: 187934941

Centisome position: 61.7

GC content: 31.45

Gene sequence:

>744_bases
GTGAATAAAACTATGTTTAGTATAAAACAACAGGCTAACAAGCCAAATGTATTAGATATTTATATTTATGATAATGTAGA
GGGAGATTCATATAACTGGTGGACTGGTGAGAAAATGGAGAGTGAAACAAGTGCAAACTATATAAAACAAGTACTTGAAA
GCAATCAAAGTACAAGTGAAATCAATTTATATATTAATTCATATGGTGGAGAAGTTAAAGAAGGCTTAGGAATTTATAAC
CAACTTAAAAGACATCCTGCACAGGTTAATGTTTATATTGACGGATTTGCATGTAGCATAGCAAGTGTTATTGCTATGGT
TGGTGACAAGGTTGTGATGGGAACTAATGCATTAATGATGATCCATCATGCGTCTATTGGGTGTTATGGAAATGCAGAAG
AATTAAGAAAAGCAGCAAATGATGTTGAAGTTATTGACCAAGCAAGCTGTAGTTCATATTTAACTAAAGCAGGTGAGAAG
CTTGATGAAGCTACATTAAAACAATTATTGGATAATCAAACATGGTTAAATGCTAGTCAATGCTTAGAATATGGATTGTG
TGATGAAATTGCAGGTCAAGAGGATAAGACAATTGAAGCAGCACAACAAAGATTTAAACAAAGTATTCAAGCTCAAATTA
TGCAGGCTGAAACTCCTATAAAAGTACCTAAGCAATTTGAAAAACAAAGAAATAATTATGAAATATTAAGACAAAAATTT
ATGAAGAAAGAAGGAAATAAATAA

Upstream 100 bases:

>100_bases
TTAAAAGATACTGTTTTAAATACTGAATGGAGTGAGAAACATTGGATTACAAAAAACTATCAAGGAATAAATGAAATTAA
TTCGAAGGAAGGTGAGAATA

Downstream 100 bases:

>100_bases
TGTTATCAAAAGATATATTAAGACAACAATTAACTGAAAAATTCGGAGCAGCAATGCAATCTGAAAATCAAGAGGATATG
ATTAATGCTTTTGTTGAATT

Product: peptidase S14, ClpP

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNKTMFSIKQQANKPNVLDIYIYDNVEGDSYNWWTGEKMESETSANYIKQVLESNQSTSEINLYINSYGGEVKEGLGIYN
QLKRHPAQVNVYIDGFACSIASVIAMVGDKVVMGTNALMMIHHASIGCYGNAEELRKAANDVEVIDQASCSSYLTKAGEK
LDEATLKQLLDNQTWLNASQCLEYGLCDEIAGQEDKTIEAAQQRFKQSIQAQIMQAETPIKVPKQFEKQRNNYEILRQKF
MKKEGNK

Sequences:

>Translated_247_residues
MNKTMFSIKQQANKPNVLDIYIYDNVEGDSYNWWTGEKMESETSANYIKQVLESNQSTSEINLYINSYGGEVKEGLGIYN
QLKRHPAQVNVYIDGFACSIASVIAMVGDKVVMGTNALMMIHHASIGCYGNAEELRKAANDVEVIDQASCSSYLTKAGEK
LDEATLKQLLDNQTWLNASQCLEYGLCDEIAGQEDKTIEAAQQRFKQSIQAQIMQAETPIKVPKQFEKQRNNYEILRQKF
MKKEGNK
>Mature_247_residues
MNKTMFSIKQQANKPNVLDIYIYDNVEGDSYNWWTGEKMESETSANYIKQVLESNQSTSEINLYINSYGGEVKEGLGIYN
QLKRHPAQVNVYIDGFACSIASVIAMVGDKVVMGTNALMMIHHASIGCYGNAEELRKAANDVEVIDQASCSSYLTKAGEK
LDEATLKQLLDNQTWLNASQCLEYGLCDEIAGQEDKTIEAAQQRFKQSIQAQIMQAETPIKVPKQFEKQRNNYEILRQKF
MKKEGNK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17538017, Length=141, Percent_Identity=29.0780141843972, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 27879; Mature: 27879

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTMFSIKQQANKPNVLDIYIYDNVEGDSYNWWTGEKMESETSANYIKQVLESNQSTSE
CCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
INLYINSYGGEVKEGLGIYNQLKRHPAQVNVYIDGFACSIASVIAMVGDKVVMGTNALMM
EEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEEECCCEEEE
IHHASIGCYGNAEELRKAANDVEVIDQASCSSYLTKAGEKLDEATLKQLLDNQTWLNASQ
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
CLEYGLCDEIAGQEDKTIEAAQQRFKQSIQAQIMQAETPIKVPKQFEKQRNNYEILRQKF
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHH
MKKEGNK
HHHCCCC
>Mature Secondary Structure
MNKTMFSIKQQANKPNVLDIYIYDNVEGDSYNWWTGEKMESETSANYIKQVLESNQSTSE
CCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCE
INLYINSYGGEVKEGLGIYNQLKRHPAQVNVYIDGFACSIASVIAMVGDKVVMGTNALMM
EEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCEEECCCEEEE
IHHASIGCYGNAEELRKAANDVEVIDQASCSSYLTKAGEKLDEATLKQLLDNQTWLNASQ
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
CLEYGLCDEIAGQEDKTIEAAQQRFKQSIQAQIMQAETPIKVPKQFEKQRNNYEILRQKF
HHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHH
MKKEGNK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA