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The map label for this gene is asnC [H]

Identifier: 187933881

GI number: 187933881

Start: 158081

End: 159475

Strand: Reverse

Name: asnC [H]

Synonym: CLL_A0142

Alternate gene names: 187933881

Gene position: 159475-158081 (Counterclockwise)

Preceding gene: 187934649

Following gene: 187935051

Centisome position: 4.2

GC content: 31.76

Gene sequence:

>1395_bases
ATGAAAAATACAGTTTTAATTAAGAAAATTTATAGAGAAACTGATCAATTTCTTTCAAAGGAAGTAATGATATCAGGTTG
GATAAGAACTTTAAGAGCATCTAATGCTTTTGGTTTCATTGAAATAAATGATGGTTCTTTCTTTAAAAATATCCAAGTAG
TTTTTGATGACAAATTAGGTAACTTTAAAGAAATTTCAAAATTACCAATAAGCTCTTCAATCTCAGTTGTTGGTACATTA
GTTGCTACACCAGATGCTAAACAACCATTTGAAATTCAAGCTAAAGAAATAGTTATTGAAGGAATGTCAAATTCTGATTA
CCCACTTCAAAAGAAAAGACATACTTTTGAATACTTAAGATCAATTGCACATTTAAGACCAAGAAGTAACGCATTCTCAG
CAACATTTAGAGTACGTTCAGTTGCTGCCTTTGCAATACATAAATTCTTCCAAGAACAAGGTTTTGTATATACTCATACT
CCAATAATTACAGGTAGTGACTGTGAAGGTGCTGGGGAGATGTTTAGAGTAACTACTCTTGACCCTAAAGCCCCTGAATT
AACTAAAGAAGGAGATATTGATTATACTAAAGACTTCTTTGGTAAAGAAACTAATCTTACTGTTTCTGGTCAATTAAATG
CTGAATGTTTCGCATTAGCATTCAGAAATATATATACATTTGGACCTACATTCAGAGCTGAAAATTCTAACACTACAAGA
CATGCAGCTGAATTCTGGATGATAGAACCTGAAATAGCATTTGCTGATTTACAAGACGATATGGAACTTGCAGAAGCAAT
GCTTAAATACGTTATAAAATATGTTATGGATGAATGTCCAGAAGAATTACAATTCTTCAATTCATTTGTTGATAAAGGAT
TACTAGAAAGATTAAATCATGTTGTTTCATCAGACTTTGCTAAAGTTACATACACAGAAGCTGTTGAAATCTTAGAAAAA
TGTGATAAAGAATTTGATTATGACGTATCTTGGGGTATCGATTTACAAACTGAACACGAAAGATATCTTACAGAAGAACA
CTTTAAAAAGCCACTATTTGTAACAGATTATCCTAAAGAAATTAAAGCATTCTATATGAGAATGAATGAAGATAATAAAA
CTGTTGCTGCAACTGATCTTTTAGTACCAGGTATCGGAGAAATCATTGGTGGTAGCCAAAGAGAAGAAAGACTTGATGTT
TTAGAAGCTAGAATGGCTGAATTAGGTCTTAAGAAAGAAGATTACTGGTGGTACTTAGAATTAAGAAAATATGGAGAAAC
TAAACATGCTGGATTTGGTTTAGGATTTGAAAGATTAATCATGTACATCACTGGTATGACAAATATCAGAGATGTAATAC
CATTCCCTAGAACTCCTGGAACTTCTGAATTCTAG

Upstream 100 bases:

>100_bases
ACTTTTTTATATTTTATAAAATAAATATTAACCCATTATTATATGTTAATCATATAGATAAATTAAATATATAATGAATT
AAATTATGGAGGTCATGTAA

Downstream 100 bases:

>100_bases
AATTTTAATATTATATAAATTTAATCAATTATAATTTATAAGGGATAAAAAAGAGGGGTAAATTTATATTTTACCTCTCT
TATTTTATATCAAACATAAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MKNTVLIKKIYRETDQFLSKEVMISGWIRTLRASNAFGFIEINDGSFFKNIQVVFDDKLGNFKEISKLPISSSISVVGTL
VATPDAKQPFEIQAKEIVIEGMSNSDYPLQKKRHTFEYLRSIAHLRPRSNAFSATFRVRSVAAFAIHKFFQEQGFVYTHT
PIITGSDCEGAGEMFRVTTLDPKAPELTKEGDIDYTKDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTTR
HAAEFWMIEPEIAFADLQDDMELAEAMLKYVIKYVMDECPEELQFFNSFVDKGLLERLNHVVSSDFAKVTYTEAVEILEK
CDKEFDYDVSWGIDLQTEHERYLTEEHFKKPLFVTDYPKEIKAFYMRMNEDNKTVAATDLLVPGIGEIIGGSQREERLDV
LEARMAELGLKKEDYWWYLELRKYGETKHAGFGLGFERLIMYITGMTNIRDVIPFPRTPGTSEF

Sequences:

>Translated_464_residues
MKNTVLIKKIYRETDQFLSKEVMISGWIRTLRASNAFGFIEINDGSFFKNIQVVFDDKLGNFKEISKLPISSSISVVGTL
VATPDAKQPFEIQAKEIVIEGMSNSDYPLQKKRHTFEYLRSIAHLRPRSNAFSATFRVRSVAAFAIHKFFQEQGFVYTHT
PIITGSDCEGAGEMFRVTTLDPKAPELTKEGDIDYTKDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTTR
HAAEFWMIEPEIAFADLQDDMELAEAMLKYVIKYVMDECPEELQFFNSFVDKGLLERLNHVVSSDFAKVTYTEAVEILEK
CDKEFDYDVSWGIDLQTEHERYLTEEHFKKPLFVTDYPKEIKAFYMRMNEDNKTVAATDLLVPGIGEIIGGSQREERLDV
LEARMAELGLKKEDYWWYLELRKYGETKHAGFGLGFERLIMYITGMTNIRDVIPFPRTPGTSEF
>Mature_464_residues
MKNTVLIKKIYRETDQFLSKEVMISGWIRTLRASNAFGFIEINDGSFFKNIQVVFDDKLGNFKEISKLPISSSISVVGTL
VATPDAKQPFEIQAKEIVIEGMSNSDYPLQKKRHTFEYLRSIAHLRPRSNAFSATFRVRSVAAFAIHKFFQEQGFVYTHT
PIITGSDCEGAGEMFRVTTLDPKAPELTKEGDIDYTKDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTTR
HAAEFWMIEPEIAFADLQDDMELAEAMLKYVIKYVMDECPEELQFFNSFVDKGLLERLNHVVSSDFAKVTYTEAVEILEK
CDKEFDYDVSWGIDLQTEHERYLTEEHFKKPLFVTDYPKEIKAFYMRMNEDNKTVAATDLLVPGIGEIIGGSQREERLDV
LEARMAELGLKKEDYWWYLELRKYGETKHAGFGLGFERLIMYITGMTNIRDVIPFPRTPGTSEF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=449, Percent_Identity=45.8797327394209, Blast_Score=400, Evalue=1e-111,
Organism=Homo sapiens, GI4758762, Length=453, Percent_Identity=26.4900662251656, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI45439306, Length=354, Percent_Identity=27.9661016949153, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1787161, Length=451, Percent_Identity=58.0931263858093, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1789256, Length=486, Percent_Identity=25.5144032921811, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790571, Length=469, Percent_Identity=25.1599147121535, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788173, Length=165, Percent_Identity=29.0909090909091, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71984122, Length=460, Percent_Identity=29.3478260869565, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17556372, Length=422, Percent_Identity=31.2796208530806, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17551876, Length=484, Percent_Identity=24.1735537190083, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=489, Percent_Identity=39.0593047034765, Blast_Score=327, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6321807, Length=456, Percent_Identity=27.8508771929825, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323011, Length=342, Percent_Identity=28.9473684210526, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI19922416, Length=455, Percent_Identity=35.8241758241758, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI19921528, Length=462, Percent_Identity=26.8398268398268, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17136276, Length=339, Percent_Identity=26.8436578171091, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00152 tRNA-synt_2 [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53342; Mature: 53342

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTVLIKKIYRETDQFLSKEVMISGWIRTLRASNAFGFIEINDGSFFKNIQVVFDDKLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCC
NFKEISKLPISSSISVVGTLVATPDAKQPFEIQAKEIVIEGMSNSDYPLQKKRHTFEYLR
CHHHHHCCCCCCCHHEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
SIAHLRPRSNAFSATFRVRSVAAFAIHKFFQEQGFVYTHTPIITGSDCEGAGEMFRVTTL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEECCCCCCCCCEEEEEEC
DPKAPELTKEGDIDYTKDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTTR
CCCCCCCCCCCCCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCCH
HAAEFWMIEPEIAFADLQDDMELAEAMLKYVIKYVMDECPEELQFFNSFVDKGLLERLNH
HHHEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VVSSDFAKVTYTEAVEILEKCDKEFDYDVSWGIDLQTEHERYLTEEHFKKPLFVTDYPKE
HHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCCHHHHHHHHHCCCCCEECCCHHH
IKAFYMRMNEDNKTVAATDLLVPGIGEIIGGSQREERLDVLEARMAELGLKKEDYWWYLE
HHHHHHHCCCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
LRKYGETKHAGFGLGFERLIMYITGMTNIRDVIPFPRTPGTSEF
EECCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKNTVLIKKIYRETDQFLSKEVMISGWIRTLRASNAFGFIEINDGSFFKNIQVVFDDKLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCC
NFKEISKLPISSSISVVGTLVATPDAKQPFEIQAKEIVIEGMSNSDYPLQKKRHTFEYLR
CHHHHHCCCCCCCHHEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHH
SIAHLRPRSNAFSATFRVRSVAAFAIHKFFQEQGFVYTHTPIITGSDCEGAGEMFRVTTL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEECCCCCCCCCEEEEEEC
DPKAPELTKEGDIDYTKDFFGKETNLTVSGQLNAECFALAFRNIYTFGPTFRAENSNTTR
CCCCCCCCCCCCCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEECCCCCCCH
HAAEFWMIEPEIAFADLQDDMELAEAMLKYVIKYVMDECPEELQFFNSFVDKGLLERLNH
HHHEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
VVSSDFAKVTYTEAVEILEKCDKEFDYDVSWGIDLQTEHERYLTEEHFKKPLFVTDYPKE
HHHCCHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCCHHHHHHHHHCCCCCEECCCHHH
IKAFYMRMNEDNKTVAATDLLVPGIGEIIGGSQREERLDVLEARMAELGLKKEDYWWYLE
HHHHHHHCCCCCCEEEEHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
LRKYGETKHAGFGLGFERLIMYITGMTNIRDVIPFPRTPGTSEF
EECCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA