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The map label for this gene is yrbG [H]

Identifier: 187933818

GI number: 187933818

Start: 1099213

End: 1100205

Strand: Reverse

Name: yrbG [H]

Synonym: CLL_A1074

Alternate gene names: 187933818

Gene position: 1100205-1099213 (Counterclockwise)

Preceding gene: 187934763

Following gene: 187934635

Centisome position: 28.95

GC content: 27.59

Gene sequence:

>993_bases
ATGAATTATATTATATTGTTACTTGGCTTTGTTTTATTAATAAAAGGCGCTGATATTTTTGTAGATGGCGCTTCAATAAT
AGCTAAAAATTTAGGAATACCAGCAGTTATAGTAGGGCTTACTATCGTATCTATAGGAACAAGTGCTCCTGAACTTGCTG
TAAGCTTAATTTCAAGTCTTAATGGTAGTAACGAGATTGCAATTGGAAATGTTATTGGATCTAACATTTTTAATACTCTT
ATGGTACTGGGGACTACTGCTATAGTTTTGCCTCTTATAATTAAGAAAGCAACAGTAAAAAACGACTTTTTAGTAAATAC
TTCAGTGACTATATTGCTATTTTTATTTACATTTGATAGTTTGTTTATATCTGACACTAATACAATCTCTAGATTAGATG
GTTTTGTTTTAATTTTACTATGCATATTTTATGTTGTAGTTTTGATAAAGAAAGCAAAAAAAATGCCTAATGAAGATCTA
AAAGAATCTACTAATGAATTGAAAAACTCTTTAGTAGATTCCAATATTGAGGTTAATATTTTACATAAAGTAATATTTAT
GATAATAGGTGTTGCTGGTATAGTTGTCGGAGGAAATCTAGTTGTAGATTCAGCTACTAATATAGCGTATTCGCTTGGAA
TGAGTGAAAAATTAGTTGGATTAACTATAGTGGCTGCTGGTACATCACTTCCTGAACTTGTAACCTCTATTGTAGCAGCA
TTAAAAGGTGAAAATGATATAGCACTAGGTAATGTATTAGGTTCAAATATATTTAATATATTACTTATACTAGGTTTATC
ATCATTAATAAGCCCTATTAATGTTTCACAAGTCTTAATGACAGATTTTATTTACTTAATAGTTATTAACTTATTACTAA
TAGGATTAGTTTTCTTTAACAAATCAAAAGAAAAAAAATTAACAAGAATTGAAGGATTTTTATTAGTAGGATTATACTTA
AGTTATATGGCTTACATAGTAATAAGAAATTAA

Upstream 100 bases:

>100_bases
TTTTTTATGTATTTAAAAACTATAAAAAATTAAATGTTGATATATCAATGATACATGTATTACAATATAACTATTTATAT
AAAGAGAGAGGAACAAAAGA

Downstream 100 bases:

>100_bases
AATAAAAAGTTCATGTTTGATATATGCATAAGCAAATTGGACTGAGTAATTAAACTTAGGAATGCTAAAAATGAGTATAG
TCCCATTTTAGCTTGCTCCC

Product: K+-dependent Na+/Ca+ exchanger homolog

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNYIILLLGFVLLIKGADIFVDGASIIAKNLGIPAVIVGLTIVSIGTSAPELAVSLISSLNGSNEIAIGNVIGSNIFNTL
MVLGTTAIVLPLIIKKATVKNDFLVNTSVTILLFLFTFDSLFISDTNTISRLDGFVLILLCIFYVVVLIKKAKKMPNEDL
KESTNELKNSLVDSNIEVNILHKVIFMIIGVAGIVVGGNLVVDSATNIAYSLGMSEKLVGLTIVAAGTSLPELVTSIVAA
LKGENDIALGNVLGSNIFNILLILGLSSLISPINVSQVLMTDFIYLIVINLLLIGLVFFNKSKEKKLTRIEGFLLVGLYL
SYMAYIVIRN

Sequences:

>Translated_330_residues
MNYIILLLGFVLLIKGADIFVDGASIIAKNLGIPAVIVGLTIVSIGTSAPELAVSLISSLNGSNEIAIGNVIGSNIFNTL
MVLGTTAIVLPLIIKKATVKNDFLVNTSVTILLFLFTFDSLFISDTNTISRLDGFVLILLCIFYVVVLIKKAKKMPNEDL
KESTNELKNSLVDSNIEVNILHKVIFMIIGVAGIVVGGNLVVDSATNIAYSLGMSEKLVGLTIVAAGTSLPELVTSIVAA
LKGENDIALGNVLGSNIFNILLILGLSSLISPINVSQVLMTDFIYLIVINLLLIGLVFFNKSKEKKLTRIEGFLLVGLYL
SYMAYIVIRN
>Mature_330_residues
MNYIILLLGFVLLIKGADIFVDGASIIAKNLGIPAVIVGLTIVSIGTSAPELAVSLISSLNGSNEIAIGNVIGSNIFNTL
MVLGTTAIVLPLIIKKATVKNDFLVNTSVTILLFLFTFDSLFISDTNTISRLDGFVLILLCIFYVVVLIKKAKKMPNEDL
KESTNELKNSLVDSNIEVNILHKVIFMIIGVAGIVVGGNLVVDSATNIAYSLGMSEKLVGLTIVAAGTSLPELVTSIVAA
LKGENDIALGNVLGSNIFNILLILGLSSLISPINVSQVLMTDFIYLIVINLLLIGLVFFNKSKEKKLTRIEGFLLVGLYL
SYMAYIVIRN

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300796347, Length=140, Percent_Identity=32.8571428571429, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI9966787, Length=140, Percent_Identity=32.8571428571429, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31563526, Length=185, Percent_Identity=30.8108108108108, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4759128, Length=100, Percent_Identity=38, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1789587, Length=312, Percent_Identity=34.9358974358974, Blast_Score=148, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24583109, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583111, Length=149, Percent_Identity=30.2013422818792, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 35320; Mature: 35320

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYIILLLGFVLLIKGADIFVDGASIIAKNLGIPAVIVGLTIVSIGTSAPELAVSLISSL
CCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
NGSNEIAIGNVIGSNIFNTLMVLGTTAIVLPLIIKKATVKNDFLVNTSVTILLFLFTFDS
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHH
LFISDTNTISRLDGFVLILLCIFYVVVLIKKAKKMPNEDLKESTNELKNSLVDSNIEVNI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHH
LHKVIFMIIGVAGIVVGGNLVVDSATNIAYSLGMSEKLVGLTIVAAGTSLPELVTSIVAA
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCHHHEEEEEECCCCHHHHHHHHHHH
LKGENDIALGNVLGSNIFNILLILGLSSLISPINVSQVLMTDFIYLIVINLLLIGLVFFN
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KSKEKKLTRIEGFLLVGLYLSYMAYIVIRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYIILLLGFVLLIKGADIFVDGASIIAKNLGIPAVIVGLTIVSIGTSAPELAVSLISSL
CCHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
NGSNEIAIGNVIGSNIFNTLMVLGTTAIVLPLIIKKATVKNDFLVNTSVTILLFLFTFDS
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHH
LFISDTNTISRLDGFVLILLCIFYVVVLIKKAKKMPNEDLKESTNELKNSLVDSNIEVNI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHH
LHKVIFMIIGVAGIVVGGNLVVDSATNIAYSLGMSEKLVGLTIVAAGTSLPELVTSIVAA
HHHHHHHHHHHHHHHCCCCEEEECCCHHHHHCCCCCHHHEEEEEECCCCHHHHHHHHHHH
LKGENDIALGNVLGSNIFNILLILGLSSLISPINVSQVLMTDFIYLIVINLLLIGLVFFN
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KSKEKKLTRIEGFLLVGLYLSYMAYIVIRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]