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The map label for this gene is yeiT [H]

Identifier: 187933662

GI number: 187933662

Start: 2390529

End: 2391800

Strand: Reverse

Name: yeiT [H]

Synonym: CLL_A2318

Alternate gene names: 187933662

Gene position: 2391800-2390529 (Counterclockwise)

Preceding gene: 187932688

Following gene: 187935649

Centisome position: 62.94

GC content: 31.37

Gene sequence:

>1272_bases
TTGTATAAAAATAATAAAATGAAAAAAAACAATGAAGAATTAATAAGTCCAGTATTTGCGATAGAAGAATCTTCAAGATG
TTTACTATGTTATGATGCACCGTGCTCACAAGCATGTCCAATAGGAACGAATCCAGCTAAATTTATTCGTTCACTTCGTT
TTAGAAATTTAAAGGGAGCCGTTGAGACAATAAGAGAAAACAACATACTTGGAGGTGTGTGTGCCAGAGTATGTCCTACC
AAGAAATATTGTGAAGGCGCTTGTAGTAGAACAAGTATAGACAAGCCTATAGAAATTGCAAAGCTTCAACAATATTTAAC
TGATTATGAAAACGTATTAGGTTTAGAAATATTAAACAAAGTAGAAATTAATAAAGAAAAGGTTGCTATAGTTGGCTCAG
GTCCAAGTGGATTAGCAGCAGCAACTAAATTAGCTCAATTAGGGTATAATGTGACCGTATTTGAAAAAAGAAAAAAATTA
GGTGGCTGGTTAACTTATGGAATACCAGAAGAGAGACTATCTCAAGCAGTTGTAGATAATGAAATTGAATATATAAAAAA
CATAGGTGTAGAATTTAAAACTAATGTAAACATAGGAAAAGATGTTACAATAGATTCCTTAAGAAAGGAAGGTTACAAAG
CATTTTTAATTGCATGTGGAATGCAAAAGAGTAAAGAAGTTAAGATAAACGGTTCAGATTTAGAAGGTGTAATTAATGGT
ACAGACTTCTTAGCAGAAGTAAAGTCAACTGGAGAATATAAATTAGGAAATAAAGTTATAGTTATTGGTGGTGGAGATGT
TGCAATAGATTGCGCAATGACAGCTAAGAACTTAGGCTCAGAAGATGTTAAAATAGTTTATAGAAGAACTATAGAAAAAA
TGCCAGCTGAAAGAAAGAGTATTCAAGAAGTAATTGATTTAAATATACCTATATTTACAGGCATTAAGCCTGGTGAGATT
ATTGGAGAAAATGGAAAGGTTTCAAGATTCAAAGGAACTGGAATGTTTGATGATTCTAATTTAGATATACCTACAGAAAA
CGTTATCTTTGCAATTGGACAAGAACAAGAAGAAGTAAGTTCAATAGCTAACTTAGATCTTAATAATAAAGGAATTATTG
AAACTAAAGAATATGCAACTAATATTGATGGAGTATTTGCTTGTGGAGATATAGTTGAAGGTGATAAAACAGTTGTTTAT
GCACTTAAATTAGGAAAAGAAGCAGCAGAGAAAGTAGATCAATATTTAAACGAGAAAGAAGGTGCTAGATAA

Upstream 100 bases:

>100_bases
GTATTTATTTATGATATAATTATGAAATCATAAACAAACTTAATAGTATTTCTTAAATATTAAGATAAGATTGTTGATAC
ACAACTTAGGGGGGATCATT

Downstream 100 bases:

>100_bases
TGAGTATTATCAAAGACTTATCAATAGAATTTTGTGGAGTAAAATGTGAAAATCCATTTTTCTTATCATCATCACCAGTA
GGAAATTGCTATGAAATGTG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MYKNNKMKKNNEELISPVFAIEESSRCLLCYDAPCSQACPIGTNPAKFIRSLRFRNLKGAVETIRENNILGGVCARVCPT
KKYCEGACSRTSIDKPIEIAKLQQYLTDYENVLGLEILNKVEINKEKVAIVGSGPSGLAAATKLAQLGYNVTVFEKRKKL
GGWLTYGIPEERLSQAVVDNEIEYIKNIGVEFKTNVNIGKDVTIDSLRKEGYKAFLIACGMQKSKEVKINGSDLEGVING
TDFLAEVKSTGEYKLGNKVIVIGGGDVAIDCAMTAKNLGSEDVKIVYRRTIEKMPAERKSIQEVIDLNIPIFTGIKPGEI
IGENGKVSRFKGTGMFDDSNLDIPTENVIFAIGQEQEEVSSIANLDLNNKGIIETKEYATNIDGVFACGDIVEGDKTVVY
ALKLGKEAAEKVDQYLNEKEGAR

Sequences:

>Translated_423_residues
MYKNNKMKKNNEELISPVFAIEESSRCLLCYDAPCSQACPIGTNPAKFIRSLRFRNLKGAVETIRENNILGGVCARVCPT
KKYCEGACSRTSIDKPIEIAKLQQYLTDYENVLGLEILNKVEINKEKVAIVGSGPSGLAAATKLAQLGYNVTVFEKRKKL
GGWLTYGIPEERLSQAVVDNEIEYIKNIGVEFKTNVNIGKDVTIDSLRKEGYKAFLIACGMQKSKEVKINGSDLEGVING
TDFLAEVKSTGEYKLGNKVIVIGGGDVAIDCAMTAKNLGSEDVKIVYRRTIEKMPAERKSIQEVIDLNIPIFTGIKPGEI
IGENGKVSRFKGTGMFDDSNLDIPTENVIFAIGQEQEEVSSIANLDLNNKGIIETKEYATNIDGVFACGDIVEGDKTVVY
ALKLGKEAAEKVDQYLNEKEGAR
>Mature_423_residues
MYKNNKMKKNNEELISPVFAIEESSRCLLCYDAPCSQACPIGTNPAKFIRSLRFRNLKGAVETIRENNILGGVCARVCPT
KKYCEGACSRTSIDKPIEIAKLQQYLTDYENVLGLEILNKVEINKEKVAIVGSGPSGLAAATKLAQLGYNVTVFEKRKKL
GGWLTYGIPEERLSQAVVDNEIEYIKNIGVEFKTNVNIGKDVTIDSLRKEGYKAFLIACGMQKSKEVKINGSDLEGVING
TDFLAEVKSTGEYKLGNKVIVIGGGDVAIDCAMTAKNLGSEDVKIVYRRTIEKMPAERKSIQEVIDLNIPIFTGIKPGEI
IGENGKVSRFKGTGMFDDSNLDIPTENVIFAIGQEQEEVSSIANLDLNNKGIIETKEYATNIDGVFACGDIVEGDKTVVY
ALKLGKEAAEKVDQYLNEKEGAR

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli glutamate synthase [NADPH] small chain (GltD) and to E.coli AegA [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=442, Percent_Identity=30.0904977375566, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI237757300, Length=103, Percent_Identity=37.8640776699029, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788468, Length=421, Percent_Identity=42.9928741092637, Blast_Score=334, Evalue=6e-93,
Organism=Escherichia coli, GI87082180, Length=442, Percent_Identity=29.6380090497738, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1789606, Length=432, Percent_Identity=29.8611111111111, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1788811, Length=436, Percent_Identity=30.045871559633, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789243, Length=405, Percent_Identity=28.3950617283951, Blast_Score=146, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71984108, Length=440, Percent_Identity=31.3636363636364, Blast_Score=181, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17570289, Length=476, Percent_Identity=28.1512605042017, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17543860, Length=188, Percent_Identity=32.9787234042553, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320030, Length=305, Percent_Identity=30.1639344262295, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24640763, Length=433, Percent_Identity=30.0230946882217, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI18858217, Length=433, Percent_Identity=30.0230946882217, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28574881, Length=451, Percent_Identity=29.2682926829268, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24665539, Length=451, Percent_Identity=29.2682926829268, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24665547, Length=448, Percent_Identity=29.0178571428571, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24665543, Length=448, Percent_Identity=29.0178571428571, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 46382; Mature: 46382

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKNNKMKKNNEELISPVFAIEESSRCLLCYDAPCSQACPIGTNPAKFIRSLRFRNLKGA
CCCCCCCCCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VETIRENNILGGVCARVCPTKKYCEGACSRTSIDKPIEIAKLQQYLTDYENVLGLEILNK
HHHHHHCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VEINKEKVAIVGSGPSGLAAATKLAQLGYNVTVFEKRKKLGGWLTYGIPEERLSQAVVDN
HCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHCCCEEEECCCHHHHHHHHHHH
EIEYIKNIGVEFKTNVNIGKDVTIDSLRKEGYKAFLIACGMQKSKEVKINGSDLEGVING
HHHHHHHCCCEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCEEECC
TDFLAEVKSTGEYKLGNKVIVIGGGDVAIDCAMTAKNLGSEDVKIVYRRTIEKMPAERKS
HHHHHHHHCCCCEECCCEEEEEECCCEEEEEEEHHCCCCCHHHHHHHHHHHHHCCCHHHH
IQEVIDLNIPIFTGIKPGEIIGENGKVSRFKGTGMFDDSNLDIPTENVIFAIGQEQEEVS
HHHHHHCCCCEEECCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHH
SIANLDLNNKGIIETKEYATNIDGVFACGDIVEGDKTVVYALKLGKEAAEKVDQYLNEKE
HHHCCCCCCCCCEECHHHHCCCCCEEEECCCCCCCCEEEEEEHHCHHHHHHHHHHHHHCC
GAR
CCC
>Mature Secondary Structure
MYKNNKMKKNNEELISPVFAIEESSRCLLCYDAPCSQACPIGTNPAKFIRSLRFRNLKGA
CCCCCCCCCCCHHHHHHHHEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VETIRENNILGGVCARVCPTKKYCEGACSRTSIDKPIEIAKLQQYLTDYENVLGLEILNK
HHHHHHCCCHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VEINKEKVAIVGSGPSGLAAATKLAQLGYNVTVFEKRKKLGGWLTYGIPEERLSQAVVDN
HCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHCCCEEEECCCHHHHHHHHHHH
EIEYIKNIGVEFKTNVNIGKDVTIDSLRKEGYKAFLIACGMQKSKEVKINGSDLEGVING
HHHHHHHCCCEEEECCCCCCCCCHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCEEECC
TDFLAEVKSTGEYKLGNKVIVIGGGDVAIDCAMTAKNLGSEDVKIVYRRTIEKMPAERKS
HHHHHHHHCCCCEECCCEEEEEECCCEEEEEEEHHCCCCCHHHHHHHHHHHHHCCCHHHH
IQEVIDLNIPIFTGIKPGEIIGENGKVSRFKGTGMFDDSNLDIPTENVIFAIGQEQEEVS
HHHHHHCCCCEEECCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHH
SIANLDLNNKGIIETKEYATNIDGVFACGDIVEGDKTVVYALKLGKEAAEKVDQYLNEKE
HHHCCCCCCCCCEECHHHHCCCCCEEEECCCCCCCCEEEEEEHHCHHHHHHHHHHHHHCC
GAR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]