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The map label for this gene is prmA [H]

Identifier: 187933526

GI number: 187933526

Start: 994211

End: 995074

Strand: Reverse

Name: prmA [H]

Synonym: CLL_A0983

Alternate gene names: 187933526

Gene position: 995074-994211 (Counterclockwise)

Preceding gene: 187933705

Following gene: 187932406

Centisome position: 26.18

GC content: 26.39

Gene sequence:

>864_bases
ATGTTTATTATTACTTATAAAATACCATTTCAAAATGTAGATACTTCTATTGAAAAATTACAATTCAATGATATTTTTAA
TGTATTTTACGAAAGTCCATTAGAAATAACTACAGATGAATTTGGATATGGATATTTAGAAAAAGATGATGTTATTATTG
ACTTCAAAGTAGCTTTTGATGGTGATGAATGCAATCTTAACGAATTTACAAACAAAGTTAATTCTATTATTGAATTAACT
CCAGACAATACAATTGAAGAAAACTATAACTATGAAGAAACACATTTTCCTGCTATACATATAGATGATACTTGGGTAAT
AGCTTCTCCTGAAGAAGACTTTCCTGAAAAACAAAAAATAAATTTTATATCTCAGGGTGCTTTTGGAACTGGAATGCATG
AAACTACTCAAGATATATTAAGATATATTTTATCACAAGATTTTAGTGGATTAGATGTATTAGATATAGGTACTGGTTCT
GGAATACTTTCATTAGCTACAAGTGTTAAAAATGCTAAAAGAGTATGTGCTTTAGATATTAGAGATGTACACGAAGAAAT
AGAATTCAATTCTTCTTTAAATAATATTACTAATATTGAGACTTTTGTCGGTGATGCTTTAAATAATGAAGTAATTATAG
ATGGCAAATTTGATTGGATATACATAAATATAGGTGGAGAAGAAACTGAAATGTTTATGGATTATATAAATGATCATATA
AAAGAAAATGGTAAACTTTTAGTTTCAGGATTGGTTGAATGGAGTTTCAATTCTGTTAAAGAAAAAGTTGAAGCTAAAGG
CTATGTTATGGAACATAAAATTCAAACAAATGAATGGTGTACAGCAATATTCAATAGAAAATAA

Upstream 100 bases:

>100_bases
TTGTAAAACAAATTATCTTTTAAGTTAGTGTTAATATTATAGTATAATATTAACACTAACTTAAAAGACATCAATAAATT
CAAATACAAGGAGATTTTTT

Downstream 100 bases:

>100_bases
CTCTCTAATAGGCTATGTTTTAATATCTTGTTGATTATTTATAAATAAAGTGGACTGAGCGGTGGGGCTTAAGTATACTA
ACATAAGTATTGTTAAATTC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MFIITYKIPFQNVDTSIEKLQFNDIFNVFYESPLEITTDEFGYGYLEKDDVIIDFKVAFDGDECNLNEFTNKVNSIIELT
PDNTIEENYNYEETHFPAIHIDDTWVIASPEEDFPEKQKINFISQGAFGTGMHETTQDILRYILSQDFSGLDVLDIGTGS
GILSLATSVKNAKRVCALDIRDVHEEIEFNSSLNNITNIETFVGDALNNEVIIDGKFDWIYINIGGEETEMFMDYINDHI
KENGKLLVSGLVEWSFNSVKEKVEAKGYVMEHKIQTNEWCTAIFNRK

Sequences:

>Translated_287_residues
MFIITYKIPFQNVDTSIEKLQFNDIFNVFYESPLEITTDEFGYGYLEKDDVIIDFKVAFDGDECNLNEFTNKVNSIIELT
PDNTIEENYNYEETHFPAIHIDDTWVIASPEEDFPEKQKINFISQGAFGTGMHETTQDILRYILSQDFSGLDVLDIGTGS
GILSLATSVKNAKRVCALDIRDVHEEIEFNSSLNNITNIETFVGDALNNEVIIDGKFDWIYINIGGEETEMFMDYINDHI
KENGKLLVSGLVEWSFNSVKEKVEAKGYVMEHKIQTNEWCTAIFNRK
>Mature_287_residues
MFIITYKIPFQNVDTSIEKLQFNDIFNVFYESPLEITTDEFGYGYLEKDDVIIDFKVAFDGDECNLNEFTNKVNSIIELT
PDNTIEENYNYEETHFPAIHIDDTWVIASPEEDFPEKQKINFISQGAFGTGMHETTQDILRYILSQDFSGLDVLDIGTGS
GILSLATSVKNAKRVCALDIRDVHEEIEFNSSLNNITNIETFVGDALNNEVIIDGKFDWIYINIGGEETEMFMDYINDHI
KENGKLLVSGLVEWSFNSVKEKVEAKGYVMEHKIQTNEWCTAIFNRK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32920; Mature: 32920

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIITYKIPFQNVDTSIEKLQFNDIFNVFYESPLEITTDEFGYGYLEKDDVIIDFKVAFD
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCEEEEEEEEEC
GDECNLNEFTNKVNSIIELTPDNTIEENYNYEETHFPAIHIDDTWVIASPEEDFPEKQKI
CCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCHHHC
NFISQGAFGTGMHETTQDILRYILSQDFSGLDVLDIGTGSGILSLATSVKNAKRVCALDI
CEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEHH
RDVHEEIEFNSSLNNITNIETFVGDALNNEVIIDGKFDWIYINIGGEETEMFMDYINDHI
HHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCEEEEEEEECCCHHHHHHHHHHHHH
KENGKLLVSGLVEWSFNSVKEKVEAKGYVMEHKIQTNEWCTAIFNRK
HCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHEECCC
>Mature Secondary Structure
MFIITYKIPFQNVDTSIEKLQFNDIFNVFYESPLEITTDEFGYGYLEKDDVIIDFKVAFD
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEECCCCEEEEEEEEEC
GDECNLNEFTNKVNSIIELTPDNTIEENYNYEETHFPAIHIDDTWVIASPEEDFPEKQKI
CCCCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCHHHC
NFISQGAFGTGMHETTQDILRYILSQDFSGLDVLDIGTGSGILSLATSVKNAKRVCALDI
CEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEHH
RDVHEEIEFNSSLNNITNIETFVGDALNNEVIIDGKFDWIYINIGGEETEMFMDYINDHI
HHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCEEEEEEEECCCHHHHHHHHHHHHH
KENGKLLVSGLVEWSFNSVKEKVEAKGYVMEHKIQTNEWCTAIFNRK
HCCCEEEEEEHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]