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The map label for this gene is hsdM [C]

Identifier: 187933312

GI number: 187933312

Start: 2176055

End: 2177644

Strand: Reverse

Name: hsdM [C]

Synonym: CLL_A2081

Alternate gene names: 187933312

Gene position: 2177644-2176055 (Counterclockwise)

Preceding gene: 187934035

Following gene: 187935287

Centisome position: 57.3

GC content: 30.94

Gene sequence:

>1590_bases
ATGAATAATAATATAAAATCAATTACCAATAAATTATGGGCAATGGCAAATGAATTACGTGGAACGATGGATGCATCAGA
GTACAAAAATTATATATTGGCATTTATGTTTTATAGATATTTATCAGAACATCAAGAGGAGTATTTATTAAAGAACAATG
TCATCGATGTTATAGAGGGGGAGTCTATTAATGAATCCTATAATTCACAAGTAGATGAGTCAGAGCTTGAAGATTACCTG
CAAGATATTTCAGCAAGCTTAGGATATGCAATTGCACCAAAGGATACATGGCAGTCATTGATTGATAAAATTAATGATTC
ACAAGTTATTCCTAGTGACTATCAAACTATTTTTGATAACTTTAATAAAAATGCAGAATTAAATAAAGAAGCAGTAAAAG
ATTTCCGTGGAGTATTTAATGATATTAATTTAGGAGATTCTCGTCTTGGAAATTCTACAAATGAACGTGCTAAATCACTT
AACAACATAGTAAAGTTAGTTGATAGTATTGAATACAAAGGTAATGATGGAAAAGATATTTTAGGTGAAATATATGAATA
CTTAATTGGTCAATTTGCGGCTAGTGCTGGTAAAAAGGGTGGAGAATTCTATACACCACATCAAGTAAGTAAGATTTTAG
CTAAAGTAGTAACAGAAGGTGTAGAAAAATCAGATGAATTATTTAGTGTATATGACCCAACAATGGGATCAGGGTCTTTA
TTACTTACTGTAGGTCAAGAATTACCAAAAGGTACTCCGATGAAGTACTTTGGTCAAGAATTGAATACAACTACGTATAA
CTTGGCACGTATGAATTTAATGATGCATGGTATATCTTATAACAACATGGTATTAAGTAACGCTGATACTTTGGAAAGTG
ATTGGCCAGATGGTCCCGATGCAAAAGGTATTGATCATCCACGTAGCTTTGATGCAGTAGTTGCAAATCCACCATATTCG
GCAAAATGGGACAATGATGAAACTAAATTAAAAGACCCACGTTTTAGTGAATATGGAAAGTTGGCACCAGCTTCAAAGGC
AGATTACGCCTTTATATTGCATAGTATATATCATTTAAATAAGACTGGAACAATGGCTATTGTTTTACCTCATGGAGTTT
TGTTTAGAGGTGCAGCAGAAGGAAAAATAAGAGAAGCTTTAATCGGTAAAAATTATCTTGATACAATAATTGGATTACCA
GCAAATCTATTTTATGGAACAAGTATTCCAACGGTAATTTTAGTGTTAAAGAAGAATCGTGAAAATAAAGATATATTATT
TATTGATGCAAGTAATGATTTTGAAAAGAATAAAAATCAAAATAATTTAAGAGATGAAGATATTGATAAAATCATAAAGA
CATATAAGGAACGTAAAGACGCTCCTAAGTATGCTCATTTGGCATCTATTGAAGAAATTAGAGAAAATGATTTTAATTTA
AACATACCACGTTATGTTGATACTTTTGAGGAAGAAGAACCAATTGATTTAGAAGAAATAAATAAGCTGTTAGAACAAGA
CAATAAGGAAATTGCTGAGCTTGAAGTTGAGATTAATGAACAATTGAAGATTTTAGGCGTAAAAATTTAA

Upstream 100 bases:

>100_bases
ACCGTAAGTTAAATCACTTACAACAACAAAAGAAGGGACTTTTACAACAGATGTTTATATAAGCCACAATCAAATTAATA
AAAGAGAGGAAGTAAAAATA

Downstream 100 bases:

>100_bases
ATTTGTTGTTAGAGGGAAAGTGAGGTATTCACTTTCCCTCATTTGCTTGGGAACAGTGTAAGTTAAAACAACTTGCTAAT
TTCACAAAAGGACAAGGCTA

Product: type I restriction-modification system, M subunit

Products: NA

Alternate protein names: M.MpnORFDP [H]

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MNNNIKSITNKLWAMANELRGTMDASEYKNYILAFMFYRYLSEHQEEYLLKNNVIDVIEGESINESYNSQVDESELEDYL
QDISASLGYAIAPKDTWQSLIDKINDSQVIPSDYQTIFDNFNKNAELNKEAVKDFRGVFNDINLGDSRLGNSTNERAKSL
NNIVKLVDSIEYKGNDGKDILGEIYEYLIGQFAASAGKKGGEFYTPHQVSKILAKVVTEGVEKSDELFSVYDPTMGSGSL
LLTVGQELPKGTPMKYFGQELNTTTYNLARMNLMMHGISYNNMVLSNADTLESDWPDGPDAKGIDHPRSFDAVVANPPYS
AKWDNDETKLKDPRFSEYGKLAPASKADYAFILHSIYHLNKTGTMAIVLPHGVLFRGAAEGKIREALIGKNYLDTIIGLP
ANLFYGTSIPTVILVLKKNRENKDILFIDASNDFEKNKNQNNLRDEDIDKIIKTYKERKDAPKYAHLASIEEIRENDFNL
NIPRYVDTFEEEEPIDLEEINKLLEQDNKEIAELEVEINEQLKILGVKI

Sequences:

>Translated_529_residues
MNNNIKSITNKLWAMANELRGTMDASEYKNYILAFMFYRYLSEHQEEYLLKNNVIDVIEGESINESYNSQVDESELEDYL
QDISASLGYAIAPKDTWQSLIDKINDSQVIPSDYQTIFDNFNKNAELNKEAVKDFRGVFNDINLGDSRLGNSTNERAKSL
NNIVKLVDSIEYKGNDGKDILGEIYEYLIGQFAASAGKKGGEFYTPHQVSKILAKVVTEGVEKSDELFSVYDPTMGSGSL
LLTVGQELPKGTPMKYFGQELNTTTYNLARMNLMMHGISYNNMVLSNADTLESDWPDGPDAKGIDHPRSFDAVVANPPYS
AKWDNDETKLKDPRFSEYGKLAPASKADYAFILHSIYHLNKTGTMAIVLPHGVLFRGAAEGKIREALIGKNYLDTIIGLP
ANLFYGTSIPTVILVLKKNRENKDILFIDASNDFEKNKNQNNLRDEDIDKIIKTYKERKDAPKYAHLASIEEIRENDFNL
NIPRYVDTFEEEEPIDLEEINKLLEQDNKEIAELEVEINEQLKILGVKI
>Mature_529_residues
MNNNIKSITNKLWAMANELRGTMDASEYKNYILAFMFYRYLSEHQEEYLLKNNVIDVIEGESINESYNSQVDESELEDYL
QDISASLGYAIAPKDTWQSLIDKINDSQVIPSDYQTIFDNFNKNAELNKEAVKDFRGVFNDINLGDSRLGNSTNERAKSL
NNIVKLVDSIEYKGNDGKDILGEIYEYLIGQFAASAGKKGGEFYTPHQVSKILAKVVTEGVEKSDELFSVYDPTMGSGSL
LLTVGQELPKGTPMKYFGQELNTTTYNLARMNLMMHGISYNNMVLSNADTLESDWPDGPDAKGIDHPRSFDAVVANPPYS
AKWDNDETKLKDPRFSEYGKLAPASKADYAFILHSIYHLNKTGTMAIVLPHGVLFRGAAEGKIREALIGKNYLDTIIGLP
ANLFYGTSIPTVILVLKKNRENKDILFIDASNDFEKNKNQNNLRDEDIDKIIKTYKERKDAPKYAHLASIEEIRENDFNL
NIPRYVDTFEEEEPIDLEEINKLLEQDNKEIAELEVEINEQLKILGVKI

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=440, Percent_Identity=23.4090909090909, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 59928; Mature: 59928

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNIKSITNKLWAMANELRGTMDASEYKNYILAFMFYRYLSEHQEEYLLKNNVIDVIEG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
ESINESYNSQVDESELEDYLQDISASLGYAIAPKDTWQSLIDKINDSQVIPSDYQTIFDN
CCCCHHHCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHC
FNKNAELNKEAVKDFRGVFNDINLGDSRLGNSTNERAKSLNNIVKLVDSIEYKGNDGKDI
CCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LGEIYEYLIGQFAASAGKKGGEFYTPHQVSKILAKVVTEGVEKSDELFSVYDPTMGSGSL
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCE
LLTVGQELPKGTPMKYFGQELNTTTYNLARMNLMMHGISYNNMVLSNADTLESDWPDGPD
EEEECHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
AKGIDHPRSFDAVVANPPYSAKWDNDETKLKDPRFSEYGKLAPASKADYAFILHSIYHLN
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCC
KTGTMAIVLPHGVLFRGAAEGKIREALIGKNYLDTIIGLPANLFYGTSIPTVILVLKKNR
CCCCEEEEECCCEEEECCCCCHHHHHHHCCHHHHHHHCCCCHHHCCCCCCEEEEEEECCC
ENKDILFIDASNDFEKNKNQNNLRDEDIDKIIKTYKERKDAPKYAHLASIEEIRENDFNL
CCCCEEEEECCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
NIPRYVDTFEEEEPIDLEEINKLLEQDNKEIAELEVEINEQLKILGVKI
CCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHEEEEECCCEEEEEECC
>Mature Secondary Structure
MNNNIKSITNKLWAMANELRGTMDASEYKNYILAFMFYRYLSEHQEEYLLKNNVIDVIEG
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
ESINESYNSQVDESELEDYLQDISASLGYAIAPKDTWQSLIDKINDSQVIPSDYQTIFDN
CCCCHHHCCCCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHC
FNKNAELNKEAVKDFRGVFNDINLGDSRLGNSTNERAKSLNNIVKLVDSIEYKGNDGKDI
CCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LGEIYEYLIGQFAASAGKKGGEFYTPHQVSKILAKVVTEGVEKSDELFSVYDPTMGSGSL
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCE
LLTVGQELPKGTPMKYFGQELNTTTYNLARMNLMMHGISYNNMVLSNADTLESDWPDGPD
EEEECHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
AKGIDHPRSFDAVVANPPYSAKWDNDETKLKDPRFSEYGKLAPASKADYAFILHSIYHLN
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCC
KTGTMAIVLPHGVLFRGAAEGKIREALIGKNYLDTIIGLPANLFYGTSIPTVILVLKKNR
CCCCEEEEECCCEEEECCCCCHHHHHHHCCHHHHHHHCCCCHHHCCCCCCEEEEEEECCC
ENKDILFIDASNDFEKNKNQNNLRDEDIDKIIKTYKERKDAPKYAHLASIEEIRENDFNL
CCCCEEEEECCCCHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
NIPRYVDTFEEEEPIDLEEINKLLEQDNKEIAELEVEINEQLKILGVKI
CCCHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]