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The map label for this gene is pyrK [H]

Identifier: 187933205

GI number: 187933205

Start: 2451992

End: 2452981

Strand: Reverse

Name: pyrK [H]

Synonym: CLL_A2360

Alternate gene names: 187933205

Gene position: 2452981-2451992 (Counterclockwise)

Preceding gene: 187935697

Following gene: 187934381

Centisome position: 64.55

GC content: 28.48

Gene sequence:

>990_bases
ATGATAAAAGAATCAAGAGATTGCATAGATGCTGGTACTGAATATTGCCCTTGCAAGTTAGCAGAAACTGGTGAATGTTT
AATATGTTCTCAGCTACAAGGGGAATGTTTTTGTGATTGTTTAAATTGGAAAGGAGTTTGTATATATCAAGAATTGTTTA
ATAATGGGAATAAGGCAAAGGAGGGACGAAAAAGTTACAGCTGTTTAATTAAGGATGTAACCAATTTTAATGATGAAGCT
GTAATGATTAAATTTGAAGCACCACATAAATTAGCATTAGATTTAGTTAAGCCAGGAAGTTATATATTTGTAAGTCAAAA
TGAAAATAAATATTTTGATGTACCTATTTCTATCATGGAATCTGATATAGAAACAAATATTATAACAATATTAATAGAAG
TTAGAGGAATAAAAACTAAGAGCATTTTAAATTTGAAAGCAGAAGAAAACATAATTATTAGAGGGCCTTATTGGAATGGA
GTTTTTGGTATTAAAAATATAAATTTTCAAAAAGGAAGTAAATCATTAGTACTAGCAAGAGGTATAGGTGTAGCTCCAAT
GATGCCAGTTATAAGAAAATTACTTTCTCAAGATAATGAGGTAAAAGTTGTTATAGATAAAACACCCTTTAAAGATGATT
TTTCTAAAGAATTATTATTAAAATATTCTTTAGAAGCAAGTGAAAATGAATTACTTGATAAAGGAAAACTTTCAGATCAT
TGTAAAGTTATCATAAAAGAAGCTTTAAAGGAGGGTGTTAATTATATTCATATAGCTGGAGCTGATATTTTTACCTATGA
GGTTATTGAATATTTAGATAAATTAGATAGAAATGATATTTTATTATCGTGTTGTAATAATTTTAAGATGTGCTGTGGTG
AAGGAATTTGTGGAGCATGTACAGCAAGATTCTCTGGTCATAGAGTAAGAAGATTTTGTAAGGAGCAAGCTGATCCAAGA
AGTATATTTGAAGGGAGAAGATTTATATGA

Upstream 100 bases:

>100_bases
CATAAATATAATTTGAAAATTTTGTCACAATTTATTTGTGTCAAATTAAAATTAAAATTATAAATTATAAAGAGGAGTAA
TTTTAGCAAAAGGAGAGACG

Downstream 100 bases:

>100_bases
AGGTTGTTATTATTGGAGGAGGTTGGTCTGGATGCGCTGCAGCAATCAGTAGTAAAAAAGCAGGAGCTGATGTTGTTGTA
ATAGAGAAAACAGATCTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MIKESRDCIDAGTEYCPCKLAETGECLICSQLQGECFCDCLNWKGVCIYQELFNNGNKAKEGRKSYSCLIKDVTNFNDEA
VMIKFEAPHKLALDLVKPGSYIFVSQNENKYFDVPISIMESDIETNIITILIEVRGIKTKSILNLKAEENIIIRGPYWNG
VFGIKNINFQKGSKSLVLARGIGVAPMMPVIRKLLSQDNEVKVVIDKTPFKDDFSKELLLKYSLEASENELLDKGKLSDH
CKVIIKEALKEGVNYIHIAGADIFTYEVIEYLDKLDRNDILLSCCNNFKMCCGEGICGACTARFSGHRVRRFCKEQADPR
SIFEGRRFI

Sequences:

>Translated_329_residues
MIKESRDCIDAGTEYCPCKLAETGECLICSQLQGECFCDCLNWKGVCIYQELFNNGNKAKEGRKSYSCLIKDVTNFNDEA
VMIKFEAPHKLALDLVKPGSYIFVSQNENKYFDVPISIMESDIETNIITILIEVRGIKTKSILNLKAEENIIIRGPYWNG
VFGIKNINFQKGSKSLVLARGIGVAPMMPVIRKLLSQDNEVKVVIDKTPFKDDFSKELLLKYSLEASENELLDKGKLSDH
CKVIIKEALKEGVNYIHIAGADIFTYEVIEYLDKLDRNDILLSCCNNFKMCCGEGICGACTARFSGHRVRRFCKEQADPR
SIFEGRRFI
>Mature_329_residues
MIKESRDCIDAGTEYCPCKLAETGECLICSQLQGECFCDCLNWKGVCIYQELFNNGNKAKEGRKSYSCLIKDVTNFNDEA
VMIKFEAPHKLALDLVKPGSYIFVSQNENKYFDVPISIMESDIETNIITILIEVRGIKTKSILNLKAEENIIIRGPYWNG
VFGIKNINFQKGSKSLVLARGIGVAPMMPVIRKLLSQDNEVKVVIDKTPFKDDFSKELLLKYSLEASENELLDKGKLSDH
CKVIIKEALKEGVNYIHIAGADIFTYEVIEYLDKLDRNDILLSCCNNFKMCCGEGICGACTARFSGHRVRRFCKEQADPR
SIFEGRRFI

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 37213; Mature: 37213

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00197 2FE2S_FER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKESRDCIDAGTEYCPCKLAETGECLICSQLQGECFCDCLNWKGVCIYQELFNNGNKAK
CCCCCCCHHHCCCCCCCEECCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHCCCCCCH
EGRKSYSCLIKDVTNFNDEAVMIKFEAPHKLALDLVKPGSYIFVSQNENKYFDVPISIME
HHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCEEEEECCCCEEEECCHHHHH
SDIETNIITILIEVRGIKTKSILNLKAEENIIIRGPYWNGVFGIKNINFQKGSKSLVLAR
CCCCCCEEEEEEEECCCCEEHEEEEECCCCEEEECCCCCCEEEEECCCCCCCCCCEEEEC
GIGVAPMMPVIRKLLSQDNEVKVVIDKTPFKDDFSKELLLKYSLEASENELLDKGKLSDH
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHEEEEEECCCCHHHHHHCCCCCHH
CKVIIKEALKEGVNYIHIAGADIFTYEVIEYLDKLDRNDILLSCCNNFKMCCGEGICGAC
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCCCCHHH
TARFSGHRVRRFCKEQADPRSIFEGRRFI
HHHCCCHHHHHHHHHCCCHHHHHCCCCCC
>Mature Secondary Structure
MIKESRDCIDAGTEYCPCKLAETGECLICSQLQGECFCDCLNWKGVCIYQELFNNGNKAK
CCCCCCCHHHCCCCCCCEECCCCCCEEEEECCCCCEEEEECCCCCEEEEHHHHCCCCCCH
EGRKSYSCLIKDVTNFNDEAVMIKFEAPHKLALDLVKPGSYIFVSQNENKYFDVPISIME
HHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCEEEEECCCCEEEECCHHHHH
SDIETNIITILIEVRGIKTKSILNLKAEENIIIRGPYWNGVFGIKNINFQKGSKSLVLAR
CCCCCCEEEEEEEECCCCEEHEEEEECCCCEEEECCCCCCEEEEECCCCCCCCCCEEEEC
GIGVAPMMPVIRKLLSQDNEVKVVIDKTPFKDDFSKELLLKYSLEASENELLDKGKLSDH
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHEEEEEECCCCHHHHHHCCCCCHH
CKVIIKEALKEGVNYIHIAGADIFTYEVIEYLDKLDRNDILLSCCNNFKMCCGEGICGAC
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHCCCCCCHHH
TARFSGHRVRRFCKEQADPRSIFEGRRFI
HHHCCCHHHHHHHHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]