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The map label for this gene is ntpC [H]

Identifier: 187932505

GI number: 187932505

Start: 2939551

End: 2940552

Strand: Reverse

Name: ntpC [H]

Synonym: CLL_A2863

Alternate gene names: 187932505

Gene position: 2940552-2939551 (Counterclockwise)

Preceding gene: 187935219

Following gene: 187932947

Centisome position: 77.38

GC content: 26.85

Gene sequence:

>1002_bases
ATGGATATGATGCAATTTAGTCAAGTTATACCTAGACTAAGAGTATATGAGACAAAACTCCTTGATAAATCAAAGATTGA
CAGAATGATCGATTCCAATTCTGCCAATGAAGCATTAAAAGTGCTTCAAGAGACAGAGTATGCCAATGTTATGACAAATG
TTAAGAGAGCAGAAGACTATGAAGTTATATTAAGTGAAGAATTAAAAAGATTATTCAATTTAATGTATGAAATAAGTCCG
ATGAAATCTCTTGTAGACTTAATGAGTATTAAATATGATTATCAAAATATAAAAGTAATATTAAAAGGTATCTTTTTAAA
GAAAGATTTATCTTATCTATTAATTGATGTTGGAACTATTGAAGCTTCAAAATTAAAATATTTAGTAGAAAATAATGACT
TAAGAGACTTACCTCAAATTATGAGAGAAGCTGTTGAAGAGTCAAAGGATAAATTTGAAAACACTAAGGATCCTCAAGTA
CTTGATATTATTTTAGATAAATATATGTTTAAACAATTAGTACAAATTAAGAATGAAATAAAAGATAACTTTGTTAATAA
ATATGTAGAAGCTGTTATAGATTCTACAAACTTGAAAACTCTTTTAAGAGTTAAAAAGCAAAACAAAGGCAGGGAATTCT
TTACTTCAGTTATTATTGAAGGAGGTTCTTTAGATAAAGATAAGTTATTAGGAATGTTAAATGATGCAGTAGAAAACATA
TCTAATAAACTTGCGTTCACTAATTATAATGATTTAATAAAATCAGGTATAGAGCACTATACAAAGACAGGTTCAGTGAG
TTTATTAGAAAAGTTAGTTGATAACTATATCATGGATATAATGAAAGACGCCAAAATAATACCTTTTGGAGTTGAGCCTT
TATTAGCTTATATTTATGCAAAAGAAACAGAAATAAAGATTATAAGAATTGTAATGGTTGGCAAACTCAATAATATTTCT
GCGGAAGTAATTAGAGAAAGGCTGCGTGATATTTATGTTTAA

Upstream 100 bases:

>100_bases
CATAGAAATAAATAATACTTTCGAAGCTTTAGTAAGTTCATTAAAAGATGAAATGGGTCTTGAAGTAGCAAGAGTATTAT
TTAGTTAAGGAGGTTAACTA

Downstream 100 bases:

>100_bases
GAAAATAGGTGTAGTTGGTGATAAGGATTCAGTTTTAGCTTTTAAAGCTTTAGGTATCGACGTTTTCCCTGTAGTTGGAA
ACGAAGAAGCAAAAAAAACT

Product: V-type ATP synthase subunit C

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit C; V-type sodium pump subunit C [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDMMQFSQVIPRLRVYETKLLDKSKIDRMIDSNSANEALKVLQETEYANVMTNVKRAEDYEVILSEELKRLFNLMYEISP
MKSLVDLMSIKYDYQNIKVILKGIFLKKDLSYLLIDVGTIEASKLKYLVENNDLRDLPQIMREAVEESKDKFENTKDPQV
LDIILDKYMFKQLVQIKNEIKDNFVNKYVEAVIDSTNLKTLLRVKKQNKGREFFTSVIIEGGSLDKDKLLGMLNDAVENI
SNKLAFTNYNDLIKSGIEHYTKTGSVSLLEKLVDNYIMDIMKDAKIIPFGVEPLLAYIYAKETEIKIIRIVMVGKLNNIS
AEVIRERLRDIYV

Sequences:

>Translated_333_residues
MDMMQFSQVIPRLRVYETKLLDKSKIDRMIDSNSANEALKVLQETEYANVMTNVKRAEDYEVILSEELKRLFNLMYEISP
MKSLVDLMSIKYDYQNIKVILKGIFLKKDLSYLLIDVGTIEASKLKYLVENNDLRDLPQIMREAVEESKDKFENTKDPQV
LDIILDKYMFKQLVQIKNEIKDNFVNKYVEAVIDSTNLKTLLRVKKQNKGREFFTSVIIEGGSLDKDKLLGMLNDAVENI
SNKLAFTNYNDLIKSGIEHYTKTGSVSLLEKLVDNYIMDIMKDAKIIPFGVEPLLAYIYAKETEIKIIRIVMVGKLNNIS
AEVIRERLRDIYV
>Mature_333_residues
MDMMQFSQVIPRLRVYETKLLDKSKIDRMIDSNSANEALKVLQETEYANVMTNVKRAEDYEVILSEELKRLFNLMYEISP
MKSLVDLMSIKYDYQNIKVILKGIFLKKDLSYLLIDVGTIEASKLKYLVENNDLRDLPQIMREAVEESKDKFENTKDPQV
LDIILDKYMFKQLVQIKNEIKDNFVNKYVEAVIDSTNLKTLLRVKKQNKGREFFTSVIIEGGSLDKDKLLGMLNDAVENI
SNKLAFTNYNDLIKSGIEHYTKTGSVSLLEKLVDNYIMDIMKDAKIIPFGVEPLLAYIYAKETEIKIIRIVMVGKLNNIS
AEVIRERLRDIYV

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1527

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase V0D/AC39 subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014272
- InterPro:   IPR002843 [H]

Pfam domain/function: PF01992 vATP-synt_AC39 [H]

EC number: 3.6.3.14

Molecular weight: Translated: 38658; Mature: 38658

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMMQFSQVIPRLRVYETKLLDKSKIDRMIDSNSANEALKVLQETEYANVMTNVKRAEDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVILSEELKRLFNLMYEISPMKSLVDLMSIKYDYQNIKVILKGIFLKKDLSYLLIDVGTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHEEECCCC
EASKLKYLVENNDLRDLPQIMREAVEESKDKFENTKDPQVLDIILDKYMFKQLVQIKNEI
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KDNFVNKYVEAVIDSTNLKTLLRVKKQNKGREFFTSVIIEGGSLDKDKLLGMLNDAVENI
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SNKLAFTNYNDLIKSGIEHYTKTGSVSLLEKLVDNYIMDIMKDAKIIPFGVEPLLAYIYA
HHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KETEIKIIRIVMVGKLNNISAEVIRERLRDIYV
CCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDMMQFSQVIPRLRVYETKLLDKSKIDRMIDSNSANEALKVLQETEYANVMTNVKRAEDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EVILSEELKRLFNLMYEISPMKSLVDLMSIKYDYQNIKVILKGIFLKKDLSYLLIDVGTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHEEECCCC
EASKLKYLVENNDLRDLPQIMREAVEESKDKFENTKDPQVLDIILDKYMFKQLVQIKNEI
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KDNFVNKYVEAVIDSTNLKTLLRVKKQNKGREFFTSVIIEGGSLDKDKLLGMLNDAVENI
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SNKLAFTNYNDLIKSGIEHYTKTGSVSLLEKLVDNYIMDIMKDAKIIPFGVEPLLAYIYA
HHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KETEIKIIRIVMVGKLNNISAEVIRERLRDIYV
CCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]