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The map label for this gene is nuoG [C]

Identifier: 187932399

GI number: 187932399

Start: 2376897

End: 2378594

Strand: Reverse

Name: nuoG [C]

Synonym: CLL_A2307

Alternate gene names: 187932399

Gene position: 2378594-2376897 (Counterclockwise)

Preceding gene: 187932967

Following gene: 187935499

Centisome position: 62.59

GC content: 33.16

Gene sequence:

>1698_bases
ATGTCAAAATATATGATAATTGATGGTAACAGGGTAGAATTTGATAATGAAAAAAATATTTTAGATTTAGTAAGGAAAGC
AGGAATTGACTTACCTACATTTTGTTATTATTCTGATCTATCTATTTATGGAGCGTGTAGAATGTGTGTGGTTGAAGATG
AATGGGGAGGAATTATAGCTTCTTGCTCTACACCACCTAAGGATAAAATGTCAATTAAGACTAATACGCCTAAGCTTCAT
AAGCACCGTAAGATGATATTAGAACTTTTATTAGCATCACATTGTAGAGATTGCACTGTGTGTGAAAAGAGTGGGAAATG
TAGACTTCAAGAATTAGCTTTACGCTTTGGAGTGAAGACTATTAGATTTAAAAATGAAAATGAAAAAATTGAATTAGATA
CTTCATCTAAATCAATAGTTCGTGATCCAAGCAAGTGTATATTGTGTGGAGATTGCGTTAGAATGTGTAATGAAATACAA
AATGTTGGAGCTATTGATTTCGCATATCGTGGTTCTAATATGGTTGTTAGTCCAGCCTTTGGTAAATGTTTAGGAGAAAC
AGATTGTGTAAATTGTGGACAATGTGCAAATGTATGTCCAACGGGAGCCATTGTTGTAAAAAGCGATGTAAAGCCAGTTT
GGAAAGCGATATATAATCCTAAACAAAGAGTTGTAGCTCAAGTTGCACCTGCAGTAAGAGTTGCGTTAGGTGAAGAATTT
GGAATAAAACCTGGTGAAAACGTTATGGATAAAATAGTTGCTGCAATGAGAAAATTAGGATTTGATGAAATATATGATAC
TTCATTAACTGCTGATATGACAATAATAGAAGAATCTAATGAGTTTTTACAAAAGTTAGAATCGGGAGATGATAAACTTC
CTTTATTTACATCTTGCTGTCCAGCTTGGGTAAGATATGTGGAAACAAAACATCCAGAACTTATGAAATATGTTTCTACA
TGCAAGTCACCAATGCAAATGTTTGGATCAGTAATAAAAGAATATTTTAAAGAAAACGATTCTTTAGAAGAAAAAGAAAC
TATATCAGTAGCTATTATGCCATGTACTGCTAAGAAAGCAGAGGCAGCTAGAGAAGAATTTATAACAAATGGAATTAAAG
ATATTGATTATGTAATTACAACAACAGAATTGTGTAAGATGATTAATGAAGCGGGACTTCAATTTGATAAGATTGAACCA
GAATCTTCAGATATGCCATTTTCTTTATATTCAGGAGCAGGAGTTATATTTGGAGTTACAGGTGGTGTAACTGAAGCAGT
AATACGTGGAGTAGTTGAAGATAAGAGTTCAAAGGCTTTAAAAGAAATAGAATTTATTGGCGTTCGTGGAATGGATGGGG
TAAAAATTTGTGAAGTTCCATTTGGAGAAAAGAATCTACGTATAGGGGTAGTTAGTGGACTTGCTAATGCAGAAAACTTA
ATTGATAAGATACAAAGTGGAGAAGAACATTTTGATTTTGTTGAAGTCATGGCTTGCCCAGGAGGCTGTGTAGCAGGAGC
AGGACAACCTTTTAGTTTAAAAGAAGGAAATAAAGAAAGGGCTAAGGGTCTTTATAAGGTAGATAAGGTTACGCAAATAA
AGAGAAGTCAAGAAAATCCAGTATTAATATCTTTATATAATGGATTATTAAAAGAACGTTCTAAGGAATTATTACATGTT
CATTATGAGCATGAGTAG

Upstream 100 bases:

>100_bases
TATAAAATGTGGTGCTTGTATGGATGGATGTGCATTTAAAGCAATCCAGTTGGTTTAATAGCTCACAACGTATGAATTAG
TGAAAGGAAGGTATAAAGTT

Downstream 100 bases:

>100_bases
AAAGATAAGTAATCATATGGCCTCACCATTATTCCTATACCGCGTTTGGAAGGGGCGCATGGCTAAAAAATCGACAACTC
TAAAGTCGCCTTAGAGATTT

Product: iron hydrogenase 1

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSKYMIIDGNRVEFDNEKNILDLVRKAGIDLPTFCYYSDLSIYGACRMCVVEDEWGGIIASCSTPPKDKMSIKTNTPKLH
KHRKMILELLLASHCRDCTVCEKSGKCRLQELALRFGVKTIRFKNENEKIELDTSSKSIVRDPSKCILCGDCVRMCNEIQ
NVGAIDFAYRGSNMVVSPAFGKCLGETDCVNCGQCANVCPTGAIVVKSDVKPVWKAIYNPKQRVVAQVAPAVRVALGEEF
GIKPGENVMDKIVAAMRKLGFDEIYDTSLTADMTIIEESNEFLQKLESGDDKLPLFTSCCPAWVRYVETKHPELMKYVST
CKSPMQMFGSVIKEYFKENDSLEEKETISVAIMPCTAKKAEAAREEFITNGIKDIDYVITTTELCKMINEAGLQFDKIEP
ESSDMPFSLYSGAGVIFGVTGGVTEAVIRGVVEDKSSKALKEIEFIGVRGMDGVKICEVPFGEKNLRIGVVSGLANAENL
IDKIQSGEEHFDFVEVMACPGGCVAGAGQPFSLKEGNKERAKGLYKVDKVTQIKRSQENPVLISLYNGLLKERSKELLHV
HYEHE

Sequences:

>Translated_565_residues
MSKYMIIDGNRVEFDNEKNILDLVRKAGIDLPTFCYYSDLSIYGACRMCVVEDEWGGIIASCSTPPKDKMSIKTNTPKLH
KHRKMILELLLASHCRDCTVCEKSGKCRLQELALRFGVKTIRFKNENEKIELDTSSKSIVRDPSKCILCGDCVRMCNEIQ
NVGAIDFAYRGSNMVVSPAFGKCLGETDCVNCGQCANVCPTGAIVVKSDVKPVWKAIYNPKQRVVAQVAPAVRVALGEEF
GIKPGENVMDKIVAAMRKLGFDEIYDTSLTADMTIIEESNEFLQKLESGDDKLPLFTSCCPAWVRYVETKHPELMKYVST
CKSPMQMFGSVIKEYFKENDSLEEKETISVAIMPCTAKKAEAAREEFITNGIKDIDYVITTTELCKMINEAGLQFDKIEP
ESSDMPFSLYSGAGVIFGVTGGVTEAVIRGVVEDKSSKALKEIEFIGVRGMDGVKICEVPFGEKNLRIGVVSGLANAENL
IDKIQSGEEHFDFVEVMACPGGCVAGAGQPFSLKEGNKERAKGLYKVDKVTQIKRSQENPVLISLYNGLLKERSKELLHV
HYEHE
>Mature_564_residues
SKYMIIDGNRVEFDNEKNILDLVRKAGIDLPTFCYYSDLSIYGACRMCVVEDEWGGIIASCSTPPKDKMSIKTNTPKLHK
HRKMILELLLASHCRDCTVCEKSGKCRLQELALRFGVKTIRFKNENEKIELDTSSKSIVRDPSKCILCGDCVRMCNEIQN
VGAIDFAYRGSNMVVSPAFGKCLGETDCVNCGQCANVCPTGAIVVKSDVKPVWKAIYNPKQRVVAQVAPAVRVALGEEFG
IKPGENVMDKIVAAMRKLGFDEIYDTSLTADMTIIEESNEFLQKLESGDDKLPLFTSCCPAWVRYVETKHPELMKYVSTC
KSPMQMFGSVIKEYFKENDSLEEKETISVAIMPCTAKKAEAAREEFITNGIKDIDYVITTTELCKMINEAGLQFDKIEPE
SSDMPFSLYSGAGVIFGVTGGVTEAVIRGVVEDKSSKALKEIEFIGVRGMDGVKICEVPFGEKNLRIGVVSGLANAENLI
DKIQSGEEHFDFVEVMACPGGCVAGAGQPFSLKEGNKERAKGLYKVDKVTQIKRSQENPVLISLYNGLLKERSKELLHVH
YEHE

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=398, Percent_Identity=28.391959798995, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI6912524, Length=407, Percent_Identity=25.0614250614251, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI134284357, Length=348, Percent_Identity=27.0114942528736, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI84452151, Length=350, Percent_Identity=26.8571428571429, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI14165461, Length=448, Percent_Identity=24.7767857142857, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI33519475, Length=277, Percent_Identity=28.5198555956679, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI145693161, Length=245, Percent_Identity=26.9387755102041, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71995015, Length=386, Percent_Identity=31.0880829015544, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17565758, Length=207, Percent_Identity=31.8840579710145, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32566231, Length=207, Percent_Identity=31.8840579710145, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193209088, Length=207, Percent_Identity=31.8840579710145, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324089, Length=414, Percent_Identity=24.6376811594203, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116007470, Length=350, Percent_Identity=28, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI116007466, Length=350, Percent_Identity=28, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI116007464, Length=350, Percent_Identity=28, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI116007468, Length=350, Percent_Identity=28, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI116007462, Length=285, Percent_Identity=29.4736842105263, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI24640559, Length=197, Percent_Identity=32.994923857868, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24640557, Length=197, Percent_Identity=32.994923857868, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 62647; Mature: 62516

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYMIIDGNRVEFDNEKNILDLVRKAGIDLPTFCYYSDLSIYGACRMCVVEDEWGGIIA
CCCEEEEECCEEEECCCCCHHHHHHHCCCCCCCCCEECCCHHCCEEEEEEEECCCCCEEE
SCSTPPKDKMSIKTNTPKLHKHRKMILELLLASHCRDCTVCEKSGKCRLQELALRFGVKT
ECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCEE
IRFKNENEKIELDTSSKSIVRDPSKCILCGDCVRMCNEIQNVGAIDFAYRGSNMVVSPAF
EEEECCCCEEEEECCCCHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCCEEECCHH
GKCLGETDCVNCGQCANVCPTGAIVVKSDVKPVWKAIYNPKQRVVAQVAPAVRVALGEEF
HHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHCHHC
GIKPGENVMDKIVAAMRKLGFDEIYDTSLTADMTIIEESNEFLQKLESGDDKLPLFTSCC
CCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHH
PAWVRYVETKHPELMKYVSTCKSPMQMFGSVIKEYFKENDSLEEKETISVAIMPCTAKKA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHH
EAAREEFITNGIKDIDYVITTTELCKMINEAGLQFDKIEPESSDMPFSLYSGAGVIFGVT
HHHHHHHHHCCCCHHHHEEEHHHHHHHHHHHCCEEECCCCCCCCCCEEEECCCEEEEEEC
GGVTEAVIRGVVEDKSSKALKEIEFIGVRGMDGVKICEVPFGEKNLRIGVVSGLANAENL
CCHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCEEEECCCCCCCEEEEEECCCCHHHHH
IDKIQSGEEHFDFVEVMACPGGCVAGAGQPFSLKEGNKERAKGLYKVDKVTQIKRSQENP
HHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCC
VLISLYNGLLKERSKELLHVHYEHE
EEEHHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
SKYMIIDGNRVEFDNEKNILDLVRKAGIDLPTFCYYSDLSIYGACRMCVVEDEWGGIIA
CCEEEEECCEEEECCCCCHHHHHHHCCCCCCCCCEECCCHHCCEEEEEEEECCCCCEEE
SCSTPPKDKMSIKTNTPKLHKHRKMILELLLASHCRDCTVCEKSGKCRLQELALRFGVKT
ECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCEE
IRFKNENEKIELDTSSKSIVRDPSKCILCGDCVRMCNEIQNVGAIDFAYRGSNMVVSPAF
EEEECCCCEEEEECCCCHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCCEEECCHH
GKCLGETDCVNCGQCANVCPTGAIVVKSDVKPVWKAIYNPKQRVVAQVAPAVRVALGEEF
HHHCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHCHHC
GIKPGENVMDKIVAAMRKLGFDEIYDTSLTADMTIIEESNEFLQKLESGDDKLPLFTSCC
CCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHH
PAWVRYVETKHPELMKYVSTCKSPMQMFGSVIKEYFKENDSLEEKETISVAIMPCTAKKA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHH
EAAREEFITNGIKDIDYVITTTELCKMINEAGLQFDKIEPESSDMPFSLYSGAGVIFGVT
HHHHHHHHHCCCCHHHHEEEHHHHHHHHHHHCCEEECCCCCCCCCCEEEECCCEEEEEEC
GGVTEAVIRGVVEDKSSKALKEIEFIGVRGMDGVKICEVPFGEKNLRIGVVSGLANAENL
CCHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCEEEECCCCCCCEEEEEECCCCHHHHH
IDKIQSGEEHFDFVEVMACPGGCVAGAGQPFSLKEGNKERAKGLYKVDKVTQIKRSQENP
HHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCCC
VLISLYNGLLKERSKELLHVHYEHE
EEEHHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]