Click here to switch to the map view.

The map label for this gene is betA [H]

Identifier: 187930604

GI number: 187930604

Start: 3708389

End: 3710023

Strand: Reverse

Name: betA [H]

Synonym: Rpic_3540

Alternate gene names: 187930604

Gene position: 3710023-3708389 (Counterclockwise)

Preceding gene: 187930605

Following gene: 187930603

Centisome position: 94.1

GC content: 67.09

Gene sequence:

>1635_bases
ATGGACACCTACGACTACATCATCATCGGCGCAGGCTCCGCAGGCTGCGTCCTCGCCAACCGCCTGACCCGCGACCCCGA
CGTTTCCGTGCTGCTGCTGGAAGCCGGCGGCAAGGACGATTACCACTGGATCCACATCCCCGTCGGCTATCTGTACTGCA
TCGGCAACCCGCGCACCGACTGGCTCTATCGCACCCGCGAAGAACCCGGCTTGAACGGCCGCTCGCTCGGCTACCCGCGC
GGCCGCGTGCTGGGTGGGTGCTCGTCGATCAACGGCATGATCTACATGCGTGGTCAGCGTGAAGACTACGACGGCTGGGC
CGCCATCACCGGTGATGATTCCTGGAGGTGGGACGCCGTGCTGCCGCTGTTCAAGGCCAGCGAGAACTATCACGGCGGCG
CGAACGCATGGCACGGCGCAAACGGCGAATGGCGCGTCGAGCCGCAACGCCTGCACTGGCAGGTGCTGGAGACCTTCATC
GAGGCGGCCGTGCAGGCGGGCATCCCGCGCACGAGTGACTTCAACCGCGGCGACAACTTTGGCGTTGGCTACTTCGAGGT
CAACCAGAAGCGCGGCATCCGCTGGAACACGGCCAAGGGCTTTCTGCGCCCGGCCTCGCAGCGTCCGAACCTGACCATCG
TGACGGGTGCGCAAGTCCGGGCGCTGACGTTTGACGGCAAGCGCTGCACTGGCGTGACGTATCGCGGGGCCGGGCAGGAC
TACACGGTGGCCGCGCGCGAAGAGGTGATCCTGTCGGCGGGCGCGATCAACTCGCCGCAATTGCTGGAGCTGGCCGGCAT
TGGTCAGCCGGAACGTCTGCAGGCGCTCGGCATTCCGGTGCGCCAGGCGCTGCCGGGTGTCGGAGAAAACCTGCAGGACC
ACCTGCAACTGCGCAGCGTGGTCAAGGTGAACGGCGTGCCCACGCTCAACACGCGCGCCTCAAACTGGTGGGGCAAGGCG
CTCATCGGCATGCAATACGCGTTCAACCAGAGCGGGCCGATGAGCATGGCGCCGTCGCAGCTGGGCGTGTTCGCGCGCTC
GAACCCGCACGTGTCGCGGCCCGATGTGGAGTACCACGTGCAGCCGCTCTCGCTCGACAAGTTTGGCGATCCGCTGCACG
CGTTCAATGCGTTTACCGCGAGCGTGTGCAATCTGCGGCCGACCTCGCGCGGCACGGTGCATGTCACGTCCGCCGACCCG
TTTGCCGCGCCGACCATCGCGCCGAACTACTTGTCCACAGAGGAAGACCGCAAGGTCGCGGCCGATTCGCTGCGCCTCAC
ACGCCGCATCGTCGCGCAGCCAGCCTTGGCGCAATACAGGCCCGAGGAGTACCTGCCCGGCGCGGCGTTTCAAACCGACG
AGGAACTTGCCCGCGCCGCCGGCGAGATCGGCACGACCATCTTCCACCCGGTCGGCACGTGCCGCATGGGGCGCGCCGAT
GATGCAAACGCGGTGGTCGACGCGCAGCTGCGCGTGCGCGGGATCGAAGGCCTGCGGGTGGTCGACGCGTCCGTCATGCC
GACGATTACGTCGGGCAATACCAACTCGCCGACGATCATGATTGCGGAGAAGGCGAGCGAGATGATCCGTGCCGCGCGCA
AGGCCCGAGCCCGCGGTGAGGCCGTCCCGGCCTGA

Upstream 100 bases:

>100_bases
AGATGACGGAGTGGTTGGCTTCGCGGATTTGATTTGAAGTGAGTTGGTTGCACCACAAAAAACAAAAACCAATAACACCA
AGGAAAAGAAGCACGGAGAC

Downstream 100 bases:

>100_bases
CACCAGCTCGCGTGCCGATGACACGGGCATGACACACCGCCCGTGTCCACTGGATGCGCAATCCGCATTGCCCCGATAGG
TAACTCTACGTAACCCCCGG

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MDTYDYIIIGAGSAGCVLANRLTRDPDVSVLLLEAGGKDDYHWIHIPVGYLYCIGNPRTDWLYRTREEPGLNGRSLGYPR
GRVLGGCSSINGMIYMRGQREDYDGWAAITGDDSWRWDAVLPLFKASENYHGGANAWHGANGEWRVEPQRLHWQVLETFI
EAAVQAGIPRTSDFNRGDNFGVGYFEVNQKRGIRWNTAKGFLRPASQRPNLTIVTGAQVRALTFDGKRCTGVTYRGAGQD
YTVAAREEVILSAGAINSPQLLELAGIGQPERLQALGIPVRQALPGVGENLQDHLQLRSVVKVNGVPTLNTRASNWWGKA
LIGMQYAFNQSGPMSMAPSQLGVFARSNPHVSRPDVEYHVQPLSLDKFGDPLHAFNAFTASVCNLRPTSRGTVHVTSADP
FAAPTIAPNYLSTEEDRKVAADSLRLTRRIVAQPALAQYRPEEYLPGAAFQTDEELARAAGEIGTTIFHPVGTCRMGRAD
DANAVVDAQLRVRGIEGLRVVDASVMPTITSGNTNSPTIMIAEKASEMIRAARKARARGEAVPA

Sequences:

>Translated_544_residues
MDTYDYIIIGAGSAGCVLANRLTRDPDVSVLLLEAGGKDDYHWIHIPVGYLYCIGNPRTDWLYRTREEPGLNGRSLGYPR
GRVLGGCSSINGMIYMRGQREDYDGWAAITGDDSWRWDAVLPLFKASENYHGGANAWHGANGEWRVEPQRLHWQVLETFI
EAAVQAGIPRTSDFNRGDNFGVGYFEVNQKRGIRWNTAKGFLRPASQRPNLTIVTGAQVRALTFDGKRCTGVTYRGAGQD
YTVAAREEVILSAGAINSPQLLELAGIGQPERLQALGIPVRQALPGVGENLQDHLQLRSVVKVNGVPTLNTRASNWWGKA
LIGMQYAFNQSGPMSMAPSQLGVFARSNPHVSRPDVEYHVQPLSLDKFGDPLHAFNAFTASVCNLRPTSRGTVHVTSADP
FAAPTIAPNYLSTEEDRKVAADSLRLTRRIVAQPALAQYRPEEYLPGAAFQTDEELARAAGEIGTTIFHPVGTCRMGRAD
DANAVVDAQLRVRGIEGLRVVDASVMPTITSGNTNSPTIMIAEKASEMIRAARKARARGEAVPA
>Mature_544_residues
MDTYDYIIIGAGSAGCVLANRLTRDPDVSVLLLEAGGKDDYHWIHIPVGYLYCIGNPRTDWLYRTREEPGLNGRSLGYPR
GRVLGGCSSINGMIYMRGQREDYDGWAAITGDDSWRWDAVLPLFKASENYHGGANAWHGANGEWRVEPQRLHWQVLETFI
EAAVQAGIPRTSDFNRGDNFGVGYFEVNQKRGIRWNTAKGFLRPASQRPNLTIVTGAQVRALTFDGKRCTGVTYRGAGQD
YTVAAREEVILSAGAINSPQLLELAGIGQPERLQALGIPVRQALPGVGENLQDHLQLRSVVKVNGVPTLNTRASNWWGKA
LIGMQYAFNQSGPMSMAPSQLGVFARSNPHVSRPDVEYHVQPLSLDKFGDPLHAFNAFTASVCNLRPTSRGTVHVTSADP
FAAPTIAPNYLSTEEDRKVAADSLRLTRRIVAQPALAQYRPEEYLPGAAFQTDEELARAAGEIGTTIFHPVGTCRMGRAD
DANAVVDAQLRVRGIEGLRVVDASVMPTITSGNTNSPTIMIAEKASEMIRAARKARARGEAVPA

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=536, Percent_Identity=42.910447761194, Blast_Score=405, Evalue=1e-113,
Organism=Escherichia coli, GI1786503, Length=536, Percent_Identity=42.910447761194, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17532301, Length=549, Percent_Identity=34.4262295081967, Blast_Score=330, Evalue=1e-90,
Organism=Drosophila melanogaster, GI24642042, Length=567, Percent_Identity=35.978835978836, Blast_Score=317, Evalue=2e-86,
Organism=Drosophila melanogaster, GI45551458, Length=567, Percent_Identity=36.1552028218695, Blast_Score=316, Evalue=3e-86,
Organism=Drosophila melanogaster, GI45549471, Length=567, Percent_Identity=36.1552028218695, Blast_Score=315, Evalue=5e-86,
Organism=Drosophila melanogaster, GI24642055, Length=581, Percent_Identity=37.0051635111876, Blast_Score=315, Evalue=7e-86,
Organism=Drosophila melanogaster, GI24642059, Length=575, Percent_Identity=36.1739130434783, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI24642048, Length=572, Percent_Identity=34.7902097902098, Blast_Score=300, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24642035, Length=575, Percent_Identity=35.4782608695652, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24650267, Length=570, Percent_Identity=35.9649122807018, Blast_Score=285, Evalue=5e-77,
Organism=Drosophila melanogaster, GI17137792, Length=561, Percent_Identity=33.8680926916221, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24642037, Length=570, Percent_Identity=32.9824561403509, Blast_Score=265, Evalue=8e-71,
Organism=Drosophila melanogaster, GI24642051, Length=578, Percent_Identity=32.5259515570934, Blast_Score=265, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24642039, Length=563, Percent_Identity=33.392539964476, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI18859995, Length=566, Percent_Identity=33.9222614840989, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI18859993, Length=575, Percent_Identity=32.5217391304348, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24642057, Length=592, Percent_Identity=30.5743243243243, Blast_Score=172, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24645930, Length=578, Percent_Identity=28.3737024221453, Blast_Score=164, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 59397; Mature: 59397

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTYDYIIIGAGSAGCVLANRLTRDPDVSVLLLEAGGKDDYHWIHIPVGYLYCIGNPRTD
CCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEEEEEEECCCCCCC
WLYRTREEPGLNGRSLGYPRGRVLGGCSSINGMIYMRGQREDYDGWAAITGDDSWRWDAV
CEEEECCCCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCEEEEECCCCCEEHHC
LPLFKASENYHGGANAWHGANGEWRVEPQRLHWQVLETFIEAAVQAGIPRTSDFNRGDNF
CHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GVGYFEVNQKRGIRWNTAKGFLRPASQRPNLTIVTGAQVRALTFDGKRCTGVTYRGAGQD
CEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEECCEEEEEEECCCEEECEEEECCCCC
YTVAAREEVILSAGAINSPQLLELAGIGQPERLQALGIPVRQALPGVGENLQDHLQLRSV
EEEECCCEEEEECCCCCCCCEEEEECCCCCHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
VKVNGVPTLNTRASNWWGKALIGMQYAFNQSGPMSMAPSQLGVFARSNPHVSRPDVEYHV
EEECCCCCCCCCCCCCHHHHHEEEEEEECCCCCCCCCHHHHEEEECCCCCCCCCCCEEEE
QPLSLDKFGDPLHAFNAFTASVCNLRPTSRGTVHVTSADPFAAPTIAPNYLSTEEDRKVA
EEECHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
ADSLRLTRRIVAQPALAQYRPEEYLPGAAFQTDEELARAAGEIGTTIFHPVGTCRMGRAD
HHHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCC
DANAVVDAQLRVRGIEGLRVVDASVMPTITSGNTNSPTIMIAEKASEMIRAARKARARGE
CCCEEEEEEEEEECCCCEEEECCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCC
AVPA
CCCC
>Mature Secondary Structure
MDTYDYIIIGAGSAGCVLANRLTRDPDVSVLLLEAGGKDDYHWIHIPVGYLYCIGNPRTD
CCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEEECCCCCCEEEEEEEEEEEEECCCCCCC
WLYRTREEPGLNGRSLGYPRGRVLGGCSSINGMIYMRGQREDYDGWAAITGDDSWRWDAV
CEEEECCCCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCEEEEECCCCCEEHHC
LPLFKASENYHGGANAWHGANGEWRVEPQRLHWQVLETFIEAAVQAGIPRTSDFNRGDNF
CHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GVGYFEVNQKRGIRWNTAKGFLRPASQRPNLTIVTGAQVRALTFDGKRCTGVTYRGAGQD
CEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEECCEEEEEEECCCEEECEEEECCCCC
YTVAAREEVILSAGAINSPQLLELAGIGQPERLQALGIPVRQALPGVGENLQDHLQLRSV
EEEECCCEEEEECCCCCCCCEEEEECCCCCHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
VKVNGVPTLNTRASNWWGKALIGMQYAFNQSGPMSMAPSQLGVFARSNPHVSRPDVEYHV
EEECCCCCCCCCCCCCHHHHHEEEEEEECCCCCCCCCHHHHEEEECCCCCCCCCCCEEEE
QPLSLDKFGDPLHAFNAFTASVCNLRPTSRGTVHVTSADPFAAPTIAPNYLSTEEDRKVA
EEECHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
ADSLRLTRRIVAQPALAQYRPEEYLPGAAFQTDEELARAAGEIGTTIFHPVGTCRMGRAD
HHHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCHHHHHHHHHHHCCEEECCCCCCCCCCCC
DANAVVDAQLRVRGIEGLRVVDASVMPTITSGNTNSPTIMIAEKASEMIRAARKARARGE
CCCEEEEEEEEEECCCCEEEECCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCC
AVPA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA