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The map label for this gene is aroB

Identifier: 187930314

GI number: 187930314

Start: 3396313

End: 3397419

Strand: Reverse

Name: aroB

Synonym: Rpic_3247

Alternate gene names: 187930314

Gene position: 3397419-3396313 (Counterclockwise)

Preceding gene: 187930315

Following gene: 187930313

Centisome position: 86.17

GC content: 64.14

Gene sequence:

>1107_bases
ATGATTACCGTTGATGTTGACCTTGGCGATCGCGCCTATCCGATCCACATTGGCTCGGGGCTGCTGTCCAAGGCCGAGTT
GTTCGCCCCCCACATTCGCGGCGCGCGTGCCGTGATCGTCACCAACGAGACTGTTGCGCCGCTGTATGCAGCCAAGGTCG
AAGAAGCGATTCGTTCGCTCGGCAAGGCGGTCGACACGGTCGTGCTGCCCGATGGCGAATCGTTCAAGAAGTGGGACACG
CTCAACCGCATCTTTGATGCGCTATTGACGGCAGGTGCGGACCGCAAGACCACGCTGATCGCCCTGGGCGGCGGCGTAAT
CGGCGACATGACCGGCTTTGCCGCTGCCTGCTATATGCGCGGCGTGCCGTTCATCCAGGTGCCGACGACGTTGCTGTCGC
AGGTCGATTCTTCGGTGGGCGGCAAGACGGGCATCAACCACCCGCTGGGCAAGAACATGATCGGCGCGTTCCACCAGCCG
CAAGCGGTCCTGGCCGATATCGACACGCTGCGCACCTTGCCCGCGCGTGAACTGGCTGCGGGCATGGCCGAGGTCATCAA
GCACGGCGCAATTGCCGATGCCGATTACTTCGCCTGGATCGAACAGAACATCAGGGGTCTCAACGATTGCGATACCGACC
TGATGACCGAAGCCGTGCGCGGCTCGGTGCGCATCAAGGCGGCTGTCGTGGCGCAGGACGAGCGGGAAACCGGTCTGCGT
GCCACCCTCAATTTCGGTCACACCTTTGGCCACGCCATCGAGGCCGGCCTGGGCTACGGCGAATGGCTGCACGGCGAGGC
CGTCGGCTGCGGCATGGTGATGGCGGCGGACCTCTCGCATCGCCTTGGTTTTATCGACATCGACACGCGCAACCGCATTA
CTGCGCTCACGTGTGCGGCTGACCTGCCGACGGTGGCGCCGGCCCTGGGCGTGGATCGGTTCATCGAGCTGATGCGCGTC
GACAAGAAAGCTGAGGCTGGCGAGATCAAATTCGTGCTGCTGCGCAAGCTGGGCCAGGCGTTCGTGACCACGGTGCCCGA
TGCCGACCTGCGCGCCACCTTGCTGCACGCCGTGCTGCGACCACCGACCGAAGCACCCGTCGCCTGA

Upstream 100 bases:

>100_bases
TCGCCCAGCTTGTTAATATGGTGCTGATGCAACTCGAGGTGGCTGGCATTGTCGTACCGCCCGCAGGCGCCTCCACTTCC
TCGCAAGTCTCTCCTCAGTC

Downstream 100 bases:

>100_bases
TGCGAGACGAGAGGGGCCCGATGAACGACCGATTTGATTTGCCGTCCGCGCCGTTCGATCTCGAAGGCCCTCTCGCTCCC
TACGCCGCGCATTCGGCGCA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MITVDVDLGDRAYPIHIGSGLLSKAELFAPHIRGARAVIVTNETVAPLYAAKVEEAIRSLGKAVDTVVLPDGESFKKWDT
LNRIFDALLTAGADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
QAVLADIDTLRTLPARELAAGMAEVIKHGAIADADYFAWIEQNIRGLNDCDTDLMTEAVRGSVRIKAAVVAQDERETGLR
ATLNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSHRLGFIDIDTRNRITALTCAADLPTVAPALGVDRFIELMRV
DKKAEAGEIKFVLLRKLGQAFVTTVPDADLRATLLHAVLRPPTEAPVA

Sequences:

>Translated_368_residues
MITVDVDLGDRAYPIHIGSGLLSKAELFAPHIRGARAVIVTNETVAPLYAAKVEEAIRSLGKAVDTVVLPDGESFKKWDT
LNRIFDALLTAGADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
QAVLADIDTLRTLPARELAAGMAEVIKHGAIADADYFAWIEQNIRGLNDCDTDLMTEAVRGSVRIKAAVVAQDERETGLR
ATLNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSHRLGFIDIDTRNRITALTCAADLPTVAPALGVDRFIELMRV
DKKAEAGEIKFVLLRKLGQAFVTTVPDADLRATLLHAVLRPPTEAPVA
>Mature_368_residues
MITVDVDLGDRAYPIHIGSGLLSKAELFAPHIRGARAVIVTNETVAPLYAAKVEEAIRSLGKAVDTVVLPDGESFKKWDT
LNRIFDALLTAGADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQP
QAVLADIDTLRTLPARELAAGMAEVIKHGAIADADYFAWIEQNIRGLNDCDTDLMTEAVRGSVRIKAAVVAQDERETGLR
ATLNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSHRLGFIDIDTRNRITALTCAADLPTVAPALGVDRFIELMRV
DKKAEAGEIKFVLLRKLGQAFVTTVPDADLRATLLHAVLRPPTEAPVA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=345, Percent_Identity=54.4927536231884, Blast_Score=347, Evalue=5e-97,
Organism=Saccharomyces cerevisiae, GI6320332, Length=394, Percent_Identity=38.8324873096447, Blast_Score=228, Evalue=8e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_RALPJ (B2UEG9)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900801.1
- ProteinModelPortal:   B2UEG9
- SMR:   B2UEG9
- GeneID:   6288294
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_3247
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39210; Mature: 39210

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVDVDLGDRAYPIHIGSGLLSKAELFAPHIRGARAVIVTNETVAPLYAAKVEEAIRSL
CEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
GKAVDTVVLPDGESFKKWDTLNRIFDALLTAGADRKTTLIALGGGVIGDMTGFAAACYMR
HHHHCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQPQAVLADIDTLRTLPARELAA
CCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCHHHHHH
GMAEVIKHGAIADADYFAWIEQNIRGLNDCDTDLMTEAVRGSVRIKAAVVAQDERETGLR
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEEEECCCHHCCCE
ATLNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSHRLGFIDIDTRNRITALTCAA
EEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEECC
DLPTVAPALGVDRFIELMRVDKKAEAGEIKFVLLRKLGQAFVTTVPDADLRATLLHAVLR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PPTEAPVA
CCCCCCCC
>Mature Secondary Structure
MITVDVDLGDRAYPIHIGSGLLSKAELFAPHIRGARAVIVTNETVAPLYAAKVEEAIRSL
CEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHH
GKAVDTVVLPDGESFKKWDTLNRIFDALLTAGADRKTTLIALGGGVIGDMTGFAAACYMR
HHHHCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFHQPQAVLADIDTLRTLPARELAA
CCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCHHHHHH
GMAEVIKHGAIADADYFAWIEQNIRGLNDCDTDLMTEAVRGSVRIKAAVVAQDERETGLR
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEEEECCCHHCCCE
ATLNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSHRLGFIDIDTRNRITALTCAA
EEEECCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCEEEEEECC
DLPTVAPALGVDRFIELMRVDKKAEAGEIKFVLLRKLGQAFVTTVPDADLRATLLHAVLR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PPTEAPVA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA