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The map label for this gene is aroE [H]

Identifier: 187930089

GI number: 187930089

Start: 3148807

End: 3149724

Strand: Reverse

Name: aroE [H]

Synonym: Rpic_3021

Alternate gene names: 187930089

Gene position: 3149724-3148807 (Counterclockwise)

Preceding gene: 187930090

Following gene: 187930088

Centisome position: 79.89

GC content: 67.65

Gene sequence:

>918_bases
ATGCCGTCGTCGTTTCAAGAGGCCATCCTCGCCGCCGCGAGCGCGCCGCCCACAGATCGCTATGGCGTGATCGGCAACCC
GATCGCGCACAGCAAGTCGCCCATCATCCATGCCGCGTTTGCGCAGCAGACCGGGCAGCGCATCCGCTACGACCGTATCT
ACGCCGAGTTGATCGCGTTTGACGAAACCGTGATGACCTTCGTGCGTGAAGGCGGACGCGGGCTCAACGTGACGGTGCCG
TTCAAGCTCGATGCGTATGCCATGTCGACGTCGTTGTCGCTGCGGGCGGAATCGGCCGGCGCGGTCAACACGCTCAAGTT
CGATGGTGAAGAGATTTTTGGCGACAACACCGACGGCGTCGGCCTGATGCGCGACATCACCCACAACATCGGCAACGCGC
TCGAAGGCGAGCGCGTGCTGCTACTGGGCGCGGGTGGTGCGGCGCGCGGCGTGCTGCTGCCGCTGCTGGAGCACAAGCCC
GCGCGCGTGTTCCTGGCCAACCGCACGGCCGATCGCGCCAACAGGCTGGTCGAGCGCTTCGAGGTCTCGGCCAAGCTGCA
CGAGGTTGAACTCGTGGGCGGGGGCTATGACGAGCTTGCTGCGGACGACGTTTTCGACGTCATCATCAACGCCACGGCGA
GCAGCCTGCAGGCCGAAGTGCCGCCGATCCCGACCACCGTGTTCGGCCCCAACGCGCTGGCCTACGACATGATGTACGGC
CCGCGTCCGACGGTGTTCATGGAGTTCGCCCGGCGCAACGGCGCCCGCGCATGGGACGGCCTGGGCATGCTGGTGGAGCA
GGCCGCGGAATCGTTCTTCGTCTGGCGCGGCGTGCGCCCGGACACCGCGCCGGTGCTGCTCGCCATGCGCGAAGGGCTGC
AGGGCGAAGCCGCGGTCGCGGCGCGCGCGCCTCGCTGA

Upstream 100 bases:

>100_bases
AGATGCGCAAGCGCGTCGACATCCAGGATGTGGTCGCCACGTTCAAGTTCACCCGCGCAGGCTTGGAAACCCACCTGCAG
ACCCGTTGATTTCGTCGTCC

Downstream 100 bases:

>100_bases
ACCTGGAGCGCAGCCCTGCGATGATGCGTTGGTTCGGCTACGTGATCGGCTGCTTCGTTGCGGGCGTGGTCGCACTCAAC
CTGTACTTCTTCGCTGCCAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPSSFQEAILAAASAPPTDRYGVIGNPIAHSKSPIIHAAFAQQTGQRIRYDRIYAELIAFDETVMTFVREGGRGLNVTVP
FKLDAYAMSTSLSLRAESAGAVNTLKFDGEEIFGDNTDGVGLMRDITHNIGNALEGERVLLLGAGGAARGVLLPLLEHKP
ARVFLANRTADRANRLVERFEVSAKLHEVELVGGGYDELAADDVFDVIINATASSLQAEVPPIPTTVFGPNALAYDMMYG
PRPTVFMEFARRNGARAWDGLGMLVEQAAESFFVWRGVRPDTAPVLLAMREGLQGEAAVAARAPR

Sequences:

>Translated_305_residues
MPSSFQEAILAAASAPPTDRYGVIGNPIAHSKSPIIHAAFAQQTGQRIRYDRIYAELIAFDETVMTFVREGGRGLNVTVP
FKLDAYAMSTSLSLRAESAGAVNTLKFDGEEIFGDNTDGVGLMRDITHNIGNALEGERVLLLGAGGAARGVLLPLLEHKP
ARVFLANRTADRANRLVERFEVSAKLHEVELVGGGYDELAADDVFDVIINATASSLQAEVPPIPTTVFGPNALAYDMMYG
PRPTVFMEFARRNGARAWDGLGMLVEQAAESFFVWRGVRPDTAPVLLAMREGLQGEAAVAARAPR
>Mature_304_residues
PSSFQEAILAAASAPPTDRYGVIGNPIAHSKSPIIHAAFAQQTGQRIRYDRIYAELIAFDETVMTFVREGGRGLNVTVPF
KLDAYAMSTSLSLRAESAGAVNTLKFDGEEIFGDNTDGVGLMRDITHNIGNALEGERVLLLGAGGAARGVLLPLLEHKPA
RVFLANRTADRANRLVERFEVSAKLHEVELVGGGYDELAADDVFDVIINATASSLQAEVPPIPTTVFGPNALAYDMMYGP
RPTVFMEFARRNGARAWDGLGMLVEQAAESFFVWRGVRPDTAPVLLAMREGLQGEAAVAARAPR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=277, Percent_Identity=45.1263537906137, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787983, Length=270, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=272, Percent_Identity=28.3088235294118, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 32858; Mature: 32727

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSFQEAILAAASAPPTDRYGVIGNPIAHSKSPIIHAAFAQQTGQRIRYDRIYAELIAF
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHHHHHHHHHH
DETVMTFVREGGRGLNVTVPFKLDAYAMSTSLSLRAESAGAVNTLKFDGEEIFGDNTDGV
HHHHHHHHHCCCCCEEEEEEEEEEEEEEECEEEEEECCCCCEEEEEECCHHHCCCCCCCC
GLMRDITHNIGNALEGERVLLLGAGGAARGVLLPLLEHKPARVFLANRTADRANRLVERF
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
EVSAKLHEVELVGGGYDELAADDVFDVIINATASSLQAEVPPIPTTVFGPNALAYDMMYG
HHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCC
PRPTVFMEFARRNGARAWDGLGMLVEQAAESFFVWRGVRPDTAPVLLAMREGLQGEAAVA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCEEEE
ARAPR
CCCCC
>Mature Secondary Structure 
PSSFQEAILAAASAPPTDRYGVIGNPIAHSKSPIIHAAFAQQTGQRIRYDRIYAELIAF
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCCHHHHHHHHHHHHHH
DETVMTFVREGGRGLNVTVPFKLDAYAMSTSLSLRAESAGAVNTLKFDGEEIFGDNTDGV
HHHHHHHHHCCCCCEEEEEEEEEEEEEEECEEEEEECCCCCEEEEEECCHHHCCCCCCCC
GLMRDITHNIGNALEGERVLLLGAGGAARGVLLPLLEHKPARVFLANRTADRANRLVERF
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
EVSAKLHEVELVGGGYDELAADDVFDVIINATASSLQAEVPPIPTTVFGPNALAYDMMYG
HHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCC
PRPTVFMEFARRNGARAWDGLGMLVEQAAESFFVWRGVRPDTAPVLLAMREGLQGEAAVA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCEEEE
ARAPR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA