Click here to switch to the map view.

The map label for this gene is gbpR [H]

Identifier: 187930072

GI number: 187930072

Start: 3131014

End: 3131958

Strand: Reverse

Name: gbpR [H]

Synonym: Rpic_3004

Alternate gene names: 187930072

Gene position: 3131958-3131014 (Counterclockwise)

Preceding gene: 187930079

Following gene: 187930067

Centisome position: 79.44

GC content: 66.77

Gene sequence:

>945_bases
ATGTCGAACAGCCCCTGGTATGTCCGTGCGCGCCTGAAGACGCGGCAATTGCTGTTGCTGATTGCCCTTGCCGAGGAGGG
CAACATCCACCGGGCGGCCGCCGCGCTCAACATGACGCAGCCCGCCGCCTCCAAGCTGCTGCGCGAGCTGGAGGCCATGC
TGGATGTGCAACTGTTTGAGCGCATGCCGCGCGGCATGCGGCCCACGCGCTATGGCGACGCGCTGATCCGCCACGCGCGC
GCAGTCGTCGGCAGCCTGGACCAGGCGCAGGAGGAAGTGCTCGGGCTCAAGGCGGGACACCTCGGGCACGTGGCGGTGGG
CACCATCACCTCGCCGGGCGTGCGGCTGTTGCCGCCGGTGGTGGCGCAGATCACGCGCGAGCATCCGGGGCTGCGGGTGT
CGCTGGAAATCGAAAGCAGCAACGTGTTGTTGGAACGACTGGCGCAGGACAAGCTCGACCTGGTGGTCGGTCGCCTGTTT
GCCGAGCACGACAAGCTGCATCTGCGCTACGAGCCGCTGGCCGACGAACCGGTGGTTGCGGTGGCGCGGCCGGGGCATCC
GCTGCTGGCAGAACCGTCGCTGACCTTGGCCGATGTGCAGCCGGCCACCTGGGTGGTGCCACCCATCGGCAGCGTTCTGC
GCCACCGGTTCGATTTGATGTTCCAGCGGGAGAGCCTGACAGCGCCGTCCAGCGTGGTGGAAACCTCCGCGTTGCTGTTC
CTGACGCGCATCCTTGAGCAGAGCGACATGCTGGCCGTGATCGGCACCGACGTCGCGCAGTACTACGCGTCGTATCGGAT
GCTGGCGATTCTTCCGATAGCGATGCCGTGCCAGATGGACGATTTCGGCATCATCACGCGCACCGACCGGTTGCTGTCTC
CGGCTGCGCTGCATGTGGTGCAGGCGCTGCACGAAGCAGGCCGAATGGCCTACAGCGCGGGTTGA

Upstream 100 bases:

>100_bases
TGGTTTTTTGATCGGACCGAGTGTACGGAGCGCCCTGATATCCTTCCAATGAAATATTGGCCGCGACCGATATCCGATTT
GATATCCCGAGGAAGACCCG

Downstream 100 bases:

>100_bases
ATGCCAGCGCAAAAAAAGAAAAGCCCGCAATTGCGGGCTTTTTCTGTGCGGCGATGACGTTCAGGCCGCCGGCACTGCGC
CCTGCGGCGTGAGGTGGTTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSNSPWYVRARLKTRQLLLLIALAEEGNIHRAAAALNMTQPAASKLLRELEAMLDVQLFERMPRGMRPTRYGDALIRHAR
AVVGSLDQAQEEVLGLKAGHLGHVAVGTITSPGVRLLPPVVAQITREHPGLRVSLEIESSNVLLERLAQDKLDLVVGRLF
AEHDKLHLRYEPLADEPVVAVARPGHPLLAEPSLTLADVQPATWVVPPIGSVLRHRFDLMFQRESLTAPSSVVETSALLF
LTRILEQSDMLAVIGTDVAQYYASYRMLAILPIAMPCQMDDFGIITRTDRLLSPAALHVVQALHEAGRMAYSAG

Sequences:

>Translated_314_residues
MSNSPWYVRARLKTRQLLLLIALAEEGNIHRAAAALNMTQPAASKLLRELEAMLDVQLFERMPRGMRPTRYGDALIRHAR
AVVGSLDQAQEEVLGLKAGHLGHVAVGTITSPGVRLLPPVVAQITREHPGLRVSLEIESSNVLLERLAQDKLDLVVGRLF
AEHDKLHLRYEPLADEPVVAVARPGHPLLAEPSLTLADVQPATWVVPPIGSVLRHRFDLMFQRESLTAPSSVVETSALLF
LTRILEQSDMLAVIGTDVAQYYASYRMLAILPIAMPCQMDDFGIITRTDRLLSPAALHVVQALHEAGRMAYSAG
>Mature_313_residues
SNSPWYVRARLKTRQLLLLIALAEEGNIHRAAAALNMTQPAASKLLRELEAMLDVQLFERMPRGMRPTRYGDALIRHARA
VVGSLDQAQEEVLGLKAGHLGHVAVGTITSPGVRLLPPVVAQITREHPGLRVSLEIESSNVLLERLAQDKLDLVVGRLFA
EHDKLHLRYEPLADEPVVAVARPGHPLLAEPSLTLADVQPATWVVPPIGSVLRHRFDLMFQRESLTAPSSVVETSALLFL
TRILEQSDMLAVIGTDVAQYYASYRMLAILPIAMPCQMDDFGIITRTDRLLSPAALHVVQALHEAGRMAYSAG

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=296, Percent_Identity=27.7027027027027, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787601, Length=301, Percent_Identity=26.578073089701, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=25.7839721254355, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789506, Length=267, Percent_Identity=23.5955056179775, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=262, Percent_Identity=26.3358778625954, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=203, Percent_Identity=29.5566502463054, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788297, Length=221, Percent_Identity=28.5067873303167, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=219, Percent_Identity=26.027397260274, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082024, Length=176, Percent_Identity=27.8409090909091, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788481, Length=207, Percent_Identity=26.5700483091787, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34535; Mature: 34404

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSPWYVRARLKTRQLLLLIALAEEGNIHRAAAALNMTQPAASKLLRELEAMLDVQLFE
CCCCCEEEEEEHHHHEEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RMPRGMRPTRYGDALIRHARAVVGSLDQAQEEVLGLKAGHLGHVAVGTITSPGVRLLPPV
HCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHH
VAQITREHPGLRVSLEIESSNVLLERLAQDKLDLVVGRLFAEHDKLHLRYEPLADEPVVA
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEE
VARPGHPLLAEPSLTLADVQPATWVVPPIGSVLRHRFDLMFQRESLTAPSSVVETSALLF
EECCCCCCEECCCCEEECCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LTRILEQSDMLAVIGTDVAQYYASYRMLAILPIAMPCQMDDFGIITRTDRLLSPAALHVV
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHCCHHHHHHH
QALHEAGRMAYSAG
HHHHHHCCHHCCCC
>Mature Secondary Structure 
SNSPWYVRARLKTRQLLLLIALAEEGNIHRAAAALNMTQPAASKLLRELEAMLDVQLFE
CCCCEEEEEEHHHHEEEEEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RMPRGMRPTRYGDALIRHARAVVGSLDQAQEEVLGLKAGHLGHVAVGTITSPGVRLLPPV
HCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHH
VAQITREHPGLRVSLEIESSNVLLERLAQDKLDLVVGRLFAEHDKLHLRYEPLADEPVVA
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEE
VARPGHPLLAEPSLTLADVQPATWVVPPIGSVLRHRFDLMFQRESLTAPSSVVETSALLF
EECCCCCCEECCCCEEECCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LTRILEQSDMLAVIGTDVAQYYASYRMLAILPIAMPCQMDDFGIITRTDRLLSPAALHVV
HHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHCCHHHHHHH
QALHEAGRMAYSAG
HHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]