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The map label for this gene is ubiA [H]

Identifier: 187929989

GI number: 187929989

Start: 3034581

End: 3035423

Strand: Reverse

Name: ubiA [H]

Synonym: Rpic_2921

Alternate gene names: 187929989

Gene position: 3035423-3034581 (Counterclockwise)

Preceding gene: 187929990

Following gene: 187929986

Centisome position: 76.99

GC content: 61.57

Gene sequence:

>843_bases
ATGCTCTATGCGCGCCTGATGCGCATGGACAAACCGATCGGCACGCTGCTGCTGCTGTGGCCGACGCTGTGGGCGCTATG
GATGGCCGCCGATGGCCATCCGCCGGTGTCGCTGGTGGTGATCTTCACGGTCGGCACGTTCCTGATGCGCTCGGCCGGTT
GCGCGGTCAACGACTGGGCGGATCGTGACTTTGACAAGCACGTCAAGCGCACCAAGGAGCGGCCGATCACCGCGGGCCTG
ATTGCCCCCTGGGAGGCGCTGGCGGTAGCCGCGGTGCTCTCGCTCATCGCCTTCACGTTGATCCTGCCACTCAATGCGCT
GACAAAGTGGATGTCGGTGGCCGCCATCGTGATTGCCGGCACGTATCCGTTCTTCAAGCGGTTCTTCGCGATTCCGCAGG
CGTACCTCGGCATTGCGTTCGGGTTTGGGATTCCGATGGCGTACGCGGCGGTGCAGGATCAGGTGCCGGTGCTGGCGTGG
CTGATGCTTGCCGGCAATGTCTTCTGGGCCGTCGCCTACGACACGGCGTACGCGATGGTCGACCGCGATGACGATTTGCT
CATCGGCATCAAAACCTCAGCCATTACTTTTGGACGTTTTGACGTGGCGGCGATCATGCTGTGCTACGCGGGGTTCTTCG
GGATCATGGCCTGGGCTGGCCATGTGATGGCACTCAGCGTGGCGTACTGGATTGGGTTTGCCGCTGCCGTGGCGTTGTCG
CTTTGGTATTTCCCGATGCTACAGACGCGTGATCGGATGAAGTGCTTTTTTGTTTTCCGGCATAACAATTGGCTGGGGGC
CTGTTTGTTTGCCGGGGTGGCGGGGGCGTATTTGCTGCGCTAG

Upstream 100 bases:

>100_bases
GCTGCTTTCGGCGGGACTAAAATGGCGCCTTGCCTCGTGCAGGCGCCATTTTTCTTTGGTGATTTCCATGCAATCGTCCG
CTGCCCAACCCAGCCGCCTC

Downstream 100 bases:

>100_bases
GTGTTGGTGGTGCGTCCCCGATTTCATCCCCTGCCGGGGACGATACCGGGGATGGACCAGTACCCTCAATCCCGCCCAAA
CTCCTCCCCCATCTCCTTGC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MLYARLMRMDKPIGTLLLLWPTLWALWMAADGHPPVSLVVIFTVGTFLMRSAGCAVNDWADRDFDKHVKRTKERPITAGL
IAPWEALAVAAVLSLIAFTLILPLNALTKWMSVAAIVIAGTYPFFKRFFAIPQAYLGIAFGFGIPMAYAAVQDQVPVLAW
LMLAGNVFWAVAYDTAYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAGFFGIMAWAGHVMALSVAYWIGFAAAVALS
LWYFPMLQTRDRMKCFFVFRHNNWLGACLFAGVAGAYLLR

Sequences:

>Translated_280_residues
MLYARLMRMDKPIGTLLLLWPTLWALWMAADGHPPVSLVVIFTVGTFLMRSAGCAVNDWADRDFDKHVKRTKERPITAGL
IAPWEALAVAAVLSLIAFTLILPLNALTKWMSVAAIVIAGTYPFFKRFFAIPQAYLGIAFGFGIPMAYAAVQDQVPVLAW
LMLAGNVFWAVAYDTAYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAGFFGIMAWAGHVMALSVAYWIGFAAAVALS
LWYFPMLQTRDRMKCFFVFRHNNWLGACLFAGVAGAYLLR
>Mature_280_residues
MLYARLMRMDKPIGTLLLLWPTLWALWMAADGHPPVSLVVIFTVGTFLMRSAGCAVNDWADRDFDKHVKRTKERPITAGL
IAPWEALAVAAVLSLIAFTLILPLNALTKWMSVAAIVIAGTYPFFKRFFAIPQAYLGIAFGFGIPMAYAAVQDQVPVLAW
LMLAGNVFWAVAYDTAYAMVDRDDDLLIGIKTSAITFGRFDVAAIMLCYAGFFGIMAWAGHVMALSVAYWIGFAAAVALS
LWYFPMLQTRDRMKCFFVFRHNNWLGACLFAGVAGAYLLR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=274, Percent_Identity=32.1167883211679, Blast_Score=141, Evalue=8e-34,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=50.1818181818182, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1786631, Length=230, Percent_Identity=25.6521739130435, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17553718, Length=281, Percent_Identity=33.8078291814947, Blast_Score=154, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI32565247, Length=281, Percent_Identity=32.7402135231317, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17553720, Length=338, Percent_Identity=29.2899408284024, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=42.3357664233577, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=42.1052631578947, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324370, Length=202, Percent_Identity=37.6237623762376, Blast_Score=129, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21355567, Length=282, Percent_Identity=33.6879432624113, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31063; Mature: 31063

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYARLMRMDKPIGTLLLLWPTLWALWMAADGHPPVSLVVIFTVGTFLMRSAGCAVNDWA
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DRDFDKHVKRTKERPITAGLIAPWEALAVAAVLSLIAFTLILPLNALTKWMSVAAIVIAG
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TYPFFKRFFAIPQAYLGIAFGFGIPMAYAAVQDQVPVLAWLMLAGNVFWAVAYDTAYAMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHEEEEHHHEEEEE
DRDDDLLIGIKTSAITFGRFDVAAIMLCYAGFFGIMAWAGHVMALSVAYWIGFAAAVALS
ECCCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWYFPMLQTRDRMKCFFVFRHNNWLGACLFAGVAGAYLLR
HHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLYARLMRMDKPIGTLLLLWPTLWALWMAADGHPPVSLVVIFTVGTFLMRSAGCAVNDWA
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DRDFDKHVKRTKERPITAGLIAPWEALAVAAVLSLIAFTLILPLNALTKWMSVAAIVIAG
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TYPFFKRFFAIPQAYLGIAFGFGIPMAYAAVQDQVPVLAWLMLAGNVFWAVAYDTAYAMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHEEEEHHHEEEEE
DRDDDLLIGIKTSAITFGRFDVAAIMLCYAGFFGIMAWAGHVMALSVAYWIGFAAAVALS
ECCCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWYFPMLQTRDRMKCFFVFRHNNWLGACLFAGVAGAYLLR
HHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]