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The map label for this gene is yfeR [H]

Identifier: 187929881

GI number: 187929881

Start: 2920769

End: 2921662

Strand: Reverse

Name: yfeR [H]

Synonym: Rpic_2812

Alternate gene names: 187929881

Gene position: 2921662-2920769 (Counterclockwise)

Preceding gene: 187929883

Following gene: 187929873

Centisome position: 74.11

GC content: 66.22

Gene sequence:

>894_bases
ATGAATGTGACCTTGCGCCAGTTGCGCGTCTTTCTCGCGGTGGCACGTGCGCACAGCTTCAGCCGGGCGGGCGACACCAT
TGGCCTGACGCAACCGGCCGTGAGCCGCTCGATTTCGGAGCTGGAAGGCGAACTGGGCTTGAAGCTGCTCGATCGCACCA
CCCGCGAAGTCGTGCTGACGGAAGTGGGCCGCTCGCTGGCGACGGCGCTGGATCGCCTCGTCGCTGATCTGGACGACACG
TTGCAACAGGCGCGACAGGTGAGCGAGCAGCGGCGCGGCCGCGTTGTCGTGGCGTCCAGTCCGACCGTGTCGACCCGGTT
GATGCCGGTCTACGTGGCGGAGTGCGCGGTGCGCTATCCAGACATCCGCATGATCGTGCGTGACTCCGTGCAGGTCGACA
CGCTGCAATTGATCCGCACAGGCGGAGCCGATTTTGGGGTGGTGGTGGAACCCCTCGATACCGAAGGCCTATGGACCGAG
CCACTGCTGGTCGATCCGTTCTGCCTCGTCTGTCGCAAGGATCACCCGTTCGCGCAGCGCAGCAGTGTGCGCTGGAAAGA
TTTGCATCGCACGGCGGTCGTCCTGCTCGACCATGCTTCGGGCAGCCGCCCGCTCATCGACCGCATTTTCCTGCGCCACG
GCGTTCACCCGGACGTTGCGCAGGAGATGGGTCACAGCAGCGCCGTATTCGGCATGGTGGAAGCTGGTATCGGCGCGGGC
GTGGTGCCGTCGCTGTCGTTGCCGCTGCCGTCCTCGTCGCCATTGGTGGCGGTGCCGTTGTCCCCTAAGGAAACGCGCGC
CATCGTGCTGGCGCGTCGGCATGACCGGTCGTTGTCGCCGGCGGCCGAAGCGGCGTGGCAGATGATTCGCCGGATGGCGC
TGCCAGCCGCCTGA

Upstream 100 bases:

>100_bases
TACGTGACGGCGCGGGTTGGATGGCGGGATAGCCGCTATTGCACAACATCCCTATCTAGAATACAAATGCATTGATCGAA
TCAATTCATACGTCGTCGGC

Downstream 100 bases:

>100_bases
CGACCGGATCGCTGCGCTTACTTCGGCTGCATGCGGATGGCGCCATCCAGGCGGATGGTCTCACCATTGAGCATCGGGTT
CTCAACGATCGCACGCGCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNVTLRQLRVFLAVARAHSFSRAGDTIGLTQPAVSRSISELEGELGLKLLDRTTREVVLTEVGRSLATALDRLVADLDDT
LQQARQVSEQRRGRVVVASSPTVSTRLMPVYVAECAVRYPDIRMIVRDSVQVDTLQLIRTGGADFGVVVEPLDTEGLWTE
PLLVDPFCLVCRKDHPFAQRSSVRWKDLHRTAVVLLDHASGSRPLIDRIFLRHGVHPDVAQEMGHSSAVFGMVEAGIGAG
VVPSLSLPLPSSSPLVAVPLSPKETRAIVLARRHDRSLSPAAEAAWQMIRRMALPAA

Sequences:

>Translated_297_residues
MNVTLRQLRVFLAVARAHSFSRAGDTIGLTQPAVSRSISELEGELGLKLLDRTTREVVLTEVGRSLATALDRLVADLDDT
LQQARQVSEQRRGRVVVASSPTVSTRLMPVYVAECAVRYPDIRMIVRDSVQVDTLQLIRTGGADFGVVVEPLDTEGLWTE
PLLVDPFCLVCRKDHPFAQRSSVRWKDLHRTAVVLLDHASGSRPLIDRIFLRHGVHPDVAQEMGHSSAVFGMVEAGIGAG
VVPSLSLPLPSSSPLVAVPLSPKETRAIVLARRHDRSLSPAAEAAWQMIRRMALPAA
>Mature_297_residues
MNVTLRQLRVFLAVARAHSFSRAGDTIGLTQPAVSRSISELEGELGLKLLDRTTREVVLTEVGRSLATALDRLVADLDDT
LQQARQVSEQRRGRVVVASSPTVSTRLMPVYVAECAVRYPDIRMIVRDSVQVDTLQLIRTGGADFGVVVEPLDTEGLWTE
PLLVDPFCLVCRKDHPFAQRSSVRWKDLHRTAVVLLDHASGSRPLIDRIFLRHGVHPDVAQEMGHSSAVFGMVEAGIGAG
VVPSLSLPLPSSSPLVAVPLSPKETRAIVLARRHDRSLSPAAEAAWQMIRRMALPAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=47.2413793103448, Blast_Score=260, Evalue=8e-71,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=31.3380281690141, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI157672245, Length=289, Percent_Identity=30.1038062283737, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788481, Length=264, Percent_Identity=28.030303030303, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=27.3092369477912, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=26.2068965517241, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788887, Length=241, Percent_Identity=24.896265560166, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789204, Length=247, Percent_Identity=28.3400809716599, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=29.0502793296089, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367136, Length=242, Percent_Identity=26.8595041322314, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.0452674897119, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=22.6720647773279, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081904, Length=182, Percent_Identity=29.1208791208791, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787128, Length=151, Percent_Identity=29.8013245033113, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=23.8683127572016, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=125, Percent_Identity=32, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=242, Percent_Identity=23.9669421487603, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790208, Length=301, Percent_Identity=22.2591362126246, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32435; Mature: 32435

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLRQLRVFLAVARAHSFSRAGDTIGLTQPAVSRSISELEGELGLKLLDRTTREVVLT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EVGRSLATALDRLVADLDDTLQQARQVSEQRRGRVVVASSPTVSTRLMPVYVAECAVRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCC
DIRMIVRDSVQVDTLQLIRTGGADFGVVVEPLDTEGLWTEPLLVDPFCLVCRKDHPFAQR
CCEEEECCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHCCHHHEECCCCCCHHH
SSVRWKDLHRTAVVLLDHASGSRPLIDRIFLRHGVHPDVAQEMGHSSAVFGMVEAGIGAG
CCCCHHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCC
VVPSLSLPLPSSSPLVAVPLSPKETRAIVLARRHDRSLSPAAEAAWQMIRRMALPAA
CCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNVTLRQLRVFLAVARAHSFSRAGDTIGLTQPAVSRSISELEGELGLKLLDRTTREVVLT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
EVGRSLATALDRLVADLDDTLQQARQVSEQRRGRVVVASSPTVSTRLMPVYVAECAVRYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCC
DIRMIVRDSVQVDTLQLIRTGGADFGVVVEPLDTEGLWTEPLLVDPFCLVCRKDHPFAQR
CCEEEECCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHCCHHHEECCCCCCHHH
SSVRWKDLHRTAVVLLDHASGSRPLIDRIFLRHGVHPDVAQEMGHSSAVFGMVEAGIGAG
CCCCHHHHHHEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCC
VVPSLSLPLPSSSPLVAVPLSPKETRAIVLARRHDRSLSPAAEAAWQMIRRMALPAA
CCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]