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The map label for this gene is yhcS [C]

Identifier: 187929830

GI number: 187929830

Start: 2872513

End: 2873421

Strand: Reverse

Name: yhcS [C]

Synonym: Rpic_2761

Alternate gene names: 187929830

Gene position: 2873421-2872513 (Counterclockwise)

Preceding gene: 187929833

Following gene: 187929829

Centisome position: 72.88

GC content: 68.87

Gene sequence:

>909_bases
ATGGAGTGGAACGATTGGGAAACCTTCTGCCGCGTGGTGGAGGCCGGCAGCTTTACCGCCGCCGCCGAGGCGCTGGGCAT
CCCCAAATCGACCGCCAGCGCCGCCGTTTCACGGCTGGAAGCCGGGCTGGGCGTGCGGCTCATGACGCGCACCACGCGAC
AGTTGCGGCTGACCGAAGCGGGCTCGCACTTCTACGACGACATCGCGCCGCTGTTCGAGCGCCTGCGCGAAGTGCACGCC
GACACCACCGCGGCCAGCGAAACCGTGGCCGGCACGCTGCGCATCGCTGCGCCGTACGAAGTCGGTGCGCAGCACCTGAC
CGAACCCGTGTGCCGCACGCTGGAGAAATACCCGCATCTGCAAATCCAGGTGCACATCTCATGGGAACAGCCAGACCTGC
TAGCCAGCGGCTTCGACATCGTCTTCGTCATGGTTGACCAGGTGTTGCCGGATTCGTCGCTCGTGGCGCGCCGCGTGGTG
CTCATCCCGCGCGGCTTGTATGCATCGCCGGCCTTGCTGGCGGAACGCCCGCCGCTCAAGACGCCCGCCGACCTGGCCGG
CTGGCCCTGCCTCTCCGGGCCTGACGACGCGAGTTGGGCCTTCCGCCCCGTTGGCGAGCCCGCCGTCGAACCAATCGAAG
TCCCCATCCAGCCACGCCTGCAGACGTTGAATGCCGAAATGCGCGCCCGCGCCGCCGTGCGGGGCCTGGGCGTGGCCCGC
ATGGCGCGCTCTGTGGGCGATACGGAAGTCGCGGCCGGCCGGCTTGTGCGCGTGCTGCCCGATTTCGAGTTGACCGCGCT
GCGCGTCTACGCGTTGATGCCTGCCCGCAAGCTGGTGCCGCGCAAGGTCCGCGTGTTTCTGGATGCGCTGGAAGCGGAGG
GCGCTTCCGCCACACCTGCACCCGCCTAG

Upstream 100 bases:

>100_bases
TGCATCTTCTTTTTCCATGAACTTTGGAGTCATGAAATCAATACAAGTTCATGAATAAATCATGCCTGGTCTATAGGAAC
ACTGTCCAGTCATGCGAACA

Downstream 100 bases:

>100_bases
CCGAAGACCGGCGCCGGATGTCACAATCGGCGCTTCCCTATTCGGATTGTGAGGACCGGCGGCTATGCGTTTGCGCCAGA
TCGAAGTCTTCCGCGCCGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEWNDWETFCRVVEAGSFTAAAEALGIPKSTASAAVSRLEAGLGVRLMTRTTRQLRLTEAGSHFYDDIAPLFERLREVHA
DTTAASETVAGTLRIAAPYEVGAQHLTEPVCRTLEKYPHLQIQVHISWEQPDLLASGFDIVFVMVDQVLPDSSLVARRVV
LIPRGLYASPALLAERPPLKTPADLAGWPCLSGPDDASWAFRPVGEPAVEPIEVPIQPRLQTLNAEMRARAAVRGLGVAR
MARSVGDTEVAAGRLVRVLPDFELTALRVYALMPARKLVPRKVRVFLDALEAEGASATPAPA

Sequences:

>Translated_302_residues
MEWNDWETFCRVVEAGSFTAAAEALGIPKSTASAAVSRLEAGLGVRLMTRTTRQLRLTEAGSHFYDDIAPLFERLREVHA
DTTAASETVAGTLRIAAPYEVGAQHLTEPVCRTLEKYPHLQIQVHISWEQPDLLASGFDIVFVMVDQVLPDSSLVARRVV
LIPRGLYASPALLAERPPLKTPADLAGWPCLSGPDDASWAFRPVGEPAVEPIEVPIQPRLQTLNAEMRARAAVRGLGVAR
MARSVGDTEVAAGRLVRVLPDFELTALRVYALMPARKLVPRKVRVFLDALEAEGASATPAPA
>Mature_302_residues
MEWNDWETFCRVVEAGSFTAAAEALGIPKSTASAAVSRLEAGLGVRLMTRTTRQLRLTEAGSHFYDDIAPLFERLREVHA
DTTAASETVAGTLRIAAPYEVGAQHLTEPVCRTLEKYPHLQIQVHISWEQPDLLASGFDIVFVMVDQVLPDSSLVARRVV
LIPRGLYASPALLAERPPLKTPADLAGWPCLSGPDDASWAFRPVGEPAVEPIEVPIQPRLQTLNAEMRARAAVRGLGVAR
MARSVGDTEVAAGRLVRVLPDFELTALRVYALMPARKLVPRKVRVFLDALEAEGASATPAPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=282, Percent_Identity=31.5602836879433, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=30.4054054054054, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87081978, Length=300, Percent_Identity=26.6666666666667, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=25.6849315068493, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693193, Length=288, Percent_Identity=26.7361111111111, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787128, Length=304, Percent_Identity=25.3289473684211, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787589, Length=304, Percent_Identity=27.3026315789474, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789173, Length=246, Percent_Identity=30.0813008130081, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=31.0924369747899, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=25.2559726962457, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32801; Mature: 32801

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWNDWETFCRVVEAGSFTAAAEALGIPKSTASAAVSRLEAGLGVRLMTRTTRQLRLTEA
CCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEHHHHHEEEHHC
GSHFYDDIAPLFERLREVHADTTAASETVAGTLRIAAPYEVGAQHLTEPVCRTLEKYPHL
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCE
QIQVHISWEQPDLLASGFDIVFVMVDQVLPDSSLVARRVVLIPRGLYASPALLAERPPLK
EEEEEEECCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCHHHCCCCCCC
TPADLAGWPCLSGPDDASWAFRPVGEPAVEPIEVPIQPRLQTLNAEMRARAAVRGLGVAR
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
MARSVGDTEVAAGRLVRVLPDFELTALRVYALMPARKLVPRKVRVFLDALEAEGASATPA
HHHHCCCHHHHHHHHHEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PA
CC
>Mature Secondary Structure
MEWNDWETFCRVVEAGSFTAAAEALGIPKSTASAAVSRLEAGLGVRLMTRTTRQLRLTEA
CCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEHHHHHEEEHHC
GSHFYDDIAPLFERLREVHADTTAASETVAGTLRIAAPYEVGAQHLTEPVCRTLEKYPHL
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCE
QIQVHISWEQPDLLASGFDIVFVMVDQVLPDSSLVARRVVLIPRGLYASPALLAERPPLK
EEEEEEECCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCHHHCCCCCCC
TPADLAGWPCLSGPDDASWAFRPVGEPAVEPIEVPIQPRLQTLNAEMRARAAVRGLGVAR
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
MARSVGDTEVAAGRLVRVLPDFELTALRVYALMPARKLVPRKVRVFLDALEAEGASATPA
HHHHCCCHHHHHHHHHEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]