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The map label for this gene is sir2 [H]

Identifier: 187929760

GI number: 187929760

Start: 2800308

End: 2801969

Strand: Reverse

Name: sir2 [H]

Synonym: Rpic_2689

Alternate gene names: 187929760

Gene position: 2801969-2800308 (Counterclockwise)

Preceding gene: 187929761

Following gene: 187929759

Centisome position: 71.07

GC content: 64.08

Gene sequence:

>1662_bases
ATGTACCAATACGACGCTTACGATCACCGCCTCGTCGCCGACCGCGTCGCGCAGTTCCGCGACCAGGTGCGCCGCCGCAT
TTCGGGCGAACTGACGGAAGAAGAGTTTCTGCCGCTGCGCCTGCAGAATGGTCTGTACTACCAGCGCCACGCCTACATGC
TGCGCGTGGCGATTCCGTATGGCCACCTGCGCGCCAAGCAACTGCGCATGCTCAGCCACATCGCCGCCGAGCACGACCGC
GGCTACGGCCACTTCAGCACGCGCCAGAACATCCAGTACAACTGGATCGAGCTGGAGCAGGTGCCCGACATCCTGGCCAA
GCTGGCCTCGGTGGAAATGCACGCCATCCAGACCTCGGGCAACTGCATCCGCAACATCACGACCGACCAGTTTGCCGGCG
TGGCACCGGACGAGGTGATCGACGCGCGCCCGCTGGCGGAAATCCTGCGCCAATGGTCGACGTTCATCCCCGAGTTCGCG
TTCCTGCCGCGCAAGTTCAAGATTGCCGTGTCGGCCTCGCGAGACGACCGCGCCGTGACGCAACTGCATGACATCGGCGT
CTACGCCTATGAGAAGGACGGGCAGACGCTGCTGCGCATCCTGGCCGGCGGCGGCATGGGCCGCACGCCGATCCTGGGCG
CAATCATCAAGGAAGACCTGCCGTGGCAGCACATGCTGTCGTACATCGAGGCCGCCGTGCGCGTGTACAACCGCTACGGC
CGCCGCGACAACAAGTACAAGGCGCGTATCAAGATTCTCGTGAAGGCCATCGGCGCTGAGGAATTTGCGCGCCAGGTGGA
AGAAGAGTGGCAGCACATCAAGGACGGCCCGTCGACCATCACGCAGGCCGAGTTCGACCGCGTGGCGCAGTTCTTCGCGC
CGCCCGCGTATGAAAAGCTGGCCGACACCGACGCTGCCTATGAAAAGGCGCTACTGGAGAACAAGGCGTTCGCCCGCTGG
GTGAGCCGCAACGTGCATCCGCACCGTGTGCCGGGCTATGCCGCTGTCACGCTCTCGCTCAAGCCGGGCGCGGCGCTGCC
CCCGGGCGACGCCACGGCCGAGCAGATGGCGCTGGTGGCGGATTGGTCCGAGCGGTTCGGTTTTGGCGAGGTGCGTGTCG
CGCACGAGCAAAACCTGATCCTGCCGGACGTGAAGAAGCACGACTTGCTGGAGCTGTGGCAGCTGGCAAAGGAGCACGGC
ATGGCCACCGCCAACATCGGCCTGCTGACCGACATCATTGCGTGCCCGGGCGGTGACTTCTGCTCGCTGGCCAACGCCAA
GTCGATCCCCATCGCGCAGGCGATTCAGGCGCGCTTCGACGATCTCGATTACGTGCACGACCTGGGCGAGCTGTCGCTCA
ACATCTCGGGTTGCATCAACTCGTGCGGTCACCACCACGTCGGCAACATCGGCATCCTGGGTGTCGATAAGCACGAAGAA
GAGTGGTACCAGGTGTCGCTGGGCGGCGCACAGGGCAACGACTCGGCGATCGGCAAGATCATCGGCCCGTCGTTCAAGGC
CGAAGAAATGCCCGACGTGATCGAGCGCATCATCGATACCTTCGTCGCCAACCGCACGGAAGACGAACGCTTCATCGACA
CCTATCACCGCATCGGCATGGCCCCGTTCAAGGAACGCGTCTACGCCCGTGCAGAAGCCTGA

Upstream 100 bases:

>100_bases
TGACTGTGGCTGCTGTCGTTGAATCGGCGGCAGCGCCATAACGAAACGCATTCCCCCAATTGAATCGCACGCCGGCCCAG
CCGGATTGGACCGAACAGTC

Downstream 100 bases:

>100_bases
AAGCCGAGGGAAACGAACATGAGCAAGATCATCAAGCTGCAAAACGGTGCCCCGCAAATCGTGGCTGACGAATGGACCGT
GCTGCGCACCCCGGAAGGTG

Product: Sulfite reductase (ferredoxin)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYYQRHAYMLRVAIPYGHLRAKQLRMLSHIAAEHDR
GYGHFSTRQNIQYNWIELEQVPDILAKLASVEMHAIQTSGNCIRNITTDQFAGVAPDEVIDARPLAEILRQWSTFIPEFA
FLPRKFKIAVSASRDDRAVTQLHDIGVYAYEKDGQTLLRILAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAVRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTITQAEFDRVAQFFAPPAYEKLADTDAAYEKALLENKAFARW
VSRNVHPHRVPGYAAVTLSLKPGAALPPGDATAEQMALVADWSERFGFGEVRVAHEQNLILPDVKKHDLLELWQLAKEHG
MATANIGLLTDIIACPGGDFCSLANAKSIPIAQAIQARFDDLDYVHDLGELSLNISGCINSCGHHHVGNIGILGVDKHEE
EWYQVSLGGAQGNDSAIGKIIGPSFKAEEMPDVIERIIDTFVANRTEDERFIDTYHRIGMAPFKERVYARAEA

Sequences:

>Translated_553_residues
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYYQRHAYMLRVAIPYGHLRAKQLRMLSHIAAEHDR
GYGHFSTRQNIQYNWIELEQVPDILAKLASVEMHAIQTSGNCIRNITTDQFAGVAPDEVIDARPLAEILRQWSTFIPEFA
FLPRKFKIAVSASRDDRAVTQLHDIGVYAYEKDGQTLLRILAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAVRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTITQAEFDRVAQFFAPPAYEKLADTDAAYEKALLENKAFARW
VSRNVHPHRVPGYAAVTLSLKPGAALPPGDATAEQMALVADWSERFGFGEVRVAHEQNLILPDVKKHDLLELWQLAKEHG
MATANIGLLTDIIACPGGDFCSLANAKSIPIAQAIQARFDDLDYVHDLGELSLNISGCINSCGHHHVGNIGILGVDKHEE
EWYQVSLGGAQGNDSAIGKIIGPSFKAEEMPDVIERIIDTFVANRTEDERFIDTYHRIGMAPFKERVYARAEA
>Mature_553_residues
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYYQRHAYMLRVAIPYGHLRAKQLRMLSHIAAEHDR
GYGHFSTRQNIQYNWIELEQVPDILAKLASVEMHAIQTSGNCIRNITTDQFAGVAPDEVIDARPLAEILRQWSTFIPEFA
FLPRKFKIAVSASRDDRAVTQLHDIGVYAYEKDGQTLLRILAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAVRVYNRYG
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTITQAEFDRVAQFFAPPAYEKLADTDAAYEKALLENKAFARW
VSRNVHPHRVPGYAAVTLSLKPGAALPPGDATAEQMALVADWSERFGFGEVRVAHEQNLILPDVKKHDLLELWQLAKEHG
MATANIGLLTDIIACPGGDFCSLANAKSIPIAQAIQARFDDLDYVHDLGELSLNISGCINSCGHHHVGNIGILGVDKHEE
EWYQVSLGGAQGNDSAIGKIIGPSFKAEEMPDVIERIIDTFVANRTEDERFIDTYHRIGMAPFKERVYARAEA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=562, Percent_Identity=22.0640569395018, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 62401; Mature: 62401

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYYQRHAYMLRVAIPY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCEEEEECEEEEEEECCC
GHLRAKQLRMLSHIAAEHDRGYGHFSTRQNIQYNWIELEQVPDILAKLASVEMHAIQTSG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHEEECCC
NCIRNITTDQFAGVAPDEVIDARPLAEILRQWSTFIPEFAFLPRKFKIAVSASRDDRAVT
CHHHCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCHHHHH
QLHDIGVYAYEKDGQTLLRILAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAVRVYNRYG
HHHHCCEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTITQAEFDRVAQFFAPPAYEKL
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
ADTDAAYEKALLENKAFARWVSRNVHPHRVPGYAAVTLSLKPGAALPPGDATAEQMALVA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
DWSERFGFGEVRVAHEQNLILPDVKKHDLLELWQLAKEHGMATANIGLLTDIIACPGGDF
HHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCC
CSLANAKSIPIAQAIQARFDDLDYVHDLGELSLNISGCINSCGHHHVGNIGILGVDKHEE
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHEEEHHHHHHCCCCCCCCCEEEEECCCCCC
EWYQVSLGGAQGNDSAIGKIIGPSFKAEEMPDVIERIIDTFVANRTEDERFIDTYHRIGM
CEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
APFKERVYARAEA
CHHHHHHHHHCCC
>Mature Secondary Structure
MYQYDAYDHRLVADRVAQFRDQVRRRISGELTEEEFLPLRLQNGLYYQRHAYMLRVAIPY
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEECCCEEEEECEEEEEEECCC
GHLRAKQLRMLSHIAAEHDRGYGHFSTRQNIQYNWIELEQVPDILAKLASVEMHAIQTSG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHEEECCC
NCIRNITTDQFAGVAPDEVIDARPLAEILRQWSTFIPEFAFLPRKFKIAVSASRDDRAVT
CHHHCCCHHHHCCCCCHHHHCHHHHHHHHHHHHHHCCHHHHCCCEEEEEEECCCCHHHHH
QLHDIGVYAYEKDGQTLLRILAGGGMGRTPILGAIIKEDLPWQHMLSYIEAAVRVYNRYG
HHHHCCEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
RRDNKYKARIKILVKAIGAEEFARQVEEEWQHIKDGPSTITQAEFDRVAQFFAPPAYEKL
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
ADTDAAYEKALLENKAFARWVSRNVHPHRVPGYAAVTLSLKPGAALPPGDATAEQMALVA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
DWSERFGFGEVRVAHEQNLILPDVKKHDLLELWQLAKEHGMATANIGLLTDIIACPGGDF
HHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCC
CSLANAKSIPIAQAIQARFDDLDYVHDLGELSLNISGCINSCGHHHVGNIGILGVDKHEE
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHEEEHHHHHHCCCCCCCCCEEEEECCCCCC
EWYQVSLGGAQGNDSAIGKIIGPSFKAEEMPDVIERIIDTFVANRTEDERFIDTYHRIGM
CEEEEEECCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
APFKERVYARAEA
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA