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The map label for this gene is ygfU [H]

Identifier: 187929337

GI number: 187929337

Start: 2374656

End: 2376065

Strand: Direct

Name: ygfU [H]

Synonym: Rpic_2258

Alternate gene names: 187929337

Gene position: 2374656-2376065 (Clockwise)

Preceding gene: 187929336

Following gene: 187929338

Centisome position: 60.23

GC content: 63.55

Gene sequence:

>1410_bases
ATGGCAAGCAGCACCATCGCCGCCCCCACGGCGGATCTGACCAATGAGCGCGTGGCGTACGGACGCCTGCTCGCATTGGG
TCTGCAACATGTATTGGTGATGTATGCAGGCACCGTGGCAGTGCCTCTGATTGTGGGCGGTGCACTGCATCTGCCCAAGG
AACAGCTCGCTTTCCTGATCAACGCGGATCTCTTTGCCGCCGGCCTTGCCACCCTCATCCAGGCCTTCGGTATTTGGAAG
TTCGGCATTCGCATGCCGGTCATGATGGGCGTGACCTTCGCATCGGTGGGCCCGATGATCGCCATCGGCACGGACCCGAG
CATCGGCCTGCTCGGCATCTACGGCGCGGTGATCGCGGCGGGGTTGTTCGGCATCATCGTCGCGCCGCTCATGGGGCGTG
TGCTTGGACTCTTCCCGCCTGTCGTGACGGGCACCGTCATCACGCTGATCGGCATGTCGCTGATGGGCGTGGGCATCAAC
TGGGCTGCCGGCGGCCAGCCGACCATGAAAACCATGGTGGACGGCGTGCTCAAGACCGTGCCGAATCCGGCCTACGGCGA
CCTGAGCGGCCTGGGCATCGCGCTGGCAGTGCTCGTGATCATCCTGTTGCTGACGAAGTACGGCCGCGGCCTGATCGGCA
ACATCGCGGTGCTGCTGGGCATCGTGATTGGCACGTTCATCGCCATGGCATTCGGCAAGGTCAGCTTTGCCGGCATTACC
GAAGCCGACTGGGTGGCCGTGATCACGCCGCTGCACTTCGGCATGCCGACCTTCCACTTCGGCGCCATCGCTTCGATGTG
CATCGTGATGATGATCACCCTGGTGGAATCGACCGGCATGTTCCTGGCGCTGGCAGAAATCACCGGCAAGAAGCTCTCCA
CCGATGACCTCACGCGCGGCCTGCGCGCCGACGGTCTGGGCACTGTGATCGGCGGTGTGTTCAACACGTTCCCGTACACG
TCGTTCTCGCAGAACGTTGGGCTGGTGACGGTGACGGGTGTGCGGTCGCGCTTCGTGGCAGCCATGGGCGGCGTGATCCT
CATCGCGCTGGGCCTGTTCCCGAAGATGGCGCACATCGTGGCATCGGTCCCTTCGTTCGTGCTGGGCGGGGCGGGCATCG
TGATGTTCGGCATGGTTGCCGCCACGGGTGTGCGCATTCTCGGCTCGATCGATTTCAACAAGTACCGCCACAACCTGTTC
ATCGTGGCGATCTCGATCGGCTTCGGCATGATCCCGACGCTGGCCCCGACCTTCTTCCAGTACCTGCCGCATTGGCTGGA
GCCCGTTACGCACAGCGGCATCGTGCTGGGCACGCTGGTCGCGGTCATCCTTAACCTGTACTACAACGGCATGCAGTCGG
CCGAGCACGCCATGCGCGACGCTGCCGCCAACACCCACGGCACGGAGTAA

Upstream 100 bases:

>100_bases
GGACGGGACGTGTCACAAGGCCAGAATCGGGGCGCGCAGCAGGAACGTGGGCAGGCTCCAAGCCGGACGCCGTCCGGCTT
ACCACCCAAAGGAGACCTTT

Downstream 100 bases:

>100_bases
TTGCATGAACGCCACTGTCGCGCACAACGACCCGCTTCTGATCGCCCGTCATGCGGACGTGCTGGTCACCATGGATGCGC
AACGCCGCGAGATCGCCGAC

Product: xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MASSTIAAPTADLTNERVAYGRLLALGLQHVLVMYAGTVAVPLIVGGALHLPKEQLAFLINADLFAAGLATLIQAFGIWK
FGIRMPVMMGVTFASVGPMIAIGTDPSIGLLGIYGAVIAAGLFGIIVAPLMGRVLGLFPPVVTGTVITLIGMSLMGVGIN
WAAGGQPTMKTMVDGVLKTVPNPAYGDLSGLGIALAVLVIILLLTKYGRGLIGNIAVLLGIVIGTFIAMAFGKVSFAGIT
EADWVAVITPLHFGMPTFHFGAIASMCIVMMITLVESTGMFLALAEITGKKLSTDDLTRGLRADGLGTVIGGVFNTFPYT
SFSQNVGLVTVTGVRSRFVAAMGGVILIALGLFPKMAHIVASVPSFVLGGAGIVMFGMVAATGVRILGSIDFNKYRHNLF
IVAISIGFGMIPTLAPTFFQYLPHWLEPVTHSGIVLGTLVAVILNLYYNGMQSAEHAMRDAAANTHGTE

Sequences:

>Translated_469_residues
MASSTIAAPTADLTNERVAYGRLLALGLQHVLVMYAGTVAVPLIVGGALHLPKEQLAFLINADLFAAGLATLIQAFGIWK
FGIRMPVMMGVTFASVGPMIAIGTDPSIGLLGIYGAVIAAGLFGIIVAPLMGRVLGLFPPVVTGTVITLIGMSLMGVGIN
WAAGGQPTMKTMVDGVLKTVPNPAYGDLSGLGIALAVLVIILLLTKYGRGLIGNIAVLLGIVIGTFIAMAFGKVSFAGIT
EADWVAVITPLHFGMPTFHFGAIASMCIVMMITLVESTGMFLALAEITGKKLSTDDLTRGLRADGLGTVIGGVFNTFPYT
SFSQNVGLVTVTGVRSRFVAAMGGVILIALGLFPKMAHIVASVPSFVLGGAGIVMFGMVAATGVRILGSIDFNKYRHNLF
IVAISIGFGMIPTLAPTFFQYLPHWLEPVTHSGIVLGTLVAVILNLYYNGMQSAEHAMRDAAANTHGTE
>Mature_468_residues
ASSTIAAPTADLTNERVAYGRLLALGLQHVLVMYAGTVAVPLIVGGALHLPKEQLAFLINADLFAAGLATLIQAFGIWKF
GIRMPVMMGVTFASVGPMIAIGTDPSIGLLGIYGAVIAAGLFGIIVAPLMGRVLGLFPPVVTGTVITLIGMSLMGVGINW
AAGGQPTMKTMVDGVLKTVPNPAYGDLSGLGIALAVLVIILLLTKYGRGLIGNIAVLLGIVIGTFIAMAFGKVSFAGITE
ADWVAVITPLHFGMPTFHFGAIASMCIVMMITLVESTGMFLALAEITGKKLSTDDLTRGLRADGLGTVIGGVFNTFPYTS
FSQNVGLVTVTGVRSRFVAAMGGVILIALGLFPKMAHIVASVPSFVLGGAGIVMFGMVAATGVRILGSIDFNKYRHNLFI
VAISIGFGMIPTLAPTFFQYLPHWLEPVTHSGIVLGTLVAVILNLYYNGMQSAEHAMRDAAANTHGTE

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=470, Percent_Identity=25.9574468085106, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI40316845, Length=470, Percent_Identity=25.9574468085106, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI44680145, Length=188, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI44680143, Length=188, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI87082181, Length=465, Percent_Identity=53.9784946236559, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1790087, Length=467, Percent_Identity=29.5503211991435, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI87082178, Length=460, Percent_Identity=27.8260869565217, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788843, Length=402, Percent_Identity=27.8606965174129, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081818, Length=415, Percent_Identity=27.9518072289157, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17558856, Length=490, Percent_Identity=24.2857142857143, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71993493, Length=494, Percent_Identity=22.0647773279352, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=430, Percent_Identity=22.093023255814, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=235, Percent_Identity=25.1063829787234, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17542262, Length=466, Percent_Identity=22.5321888412017, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356175, Length=436, Percent_Identity=26.1467889908257, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48795; Mature: 48664

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ASSTIAAPTADLTNERVAYGRLLALGLQHVLVMYAGTVAVPLIVGGALHLPKEQLAFLI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHH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HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]