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The map label for this gene is qorA [H]

Identifier: 187929296

GI number: 187929296

Start: 2326251

End: 2327255

Strand: Reverse

Name: qorA [H]

Synonym: Rpic_2217

Alternate gene names: 187929296

Gene position: 2327255-2326251 (Counterclockwise)

Preceding gene: 187929297

Following gene: 187929295

Centisome position: 59.03

GC content: 64.98

Gene sequence:

>1005_bases
ATGAAAGCGATTGAAATCACCCAGTACGGTGGCCCTGAAGTCTTGAAGCTTGGCGAGCGCCCGATGCCGGAGGCCAAGGC
CGGCGAGGTTCTGATCCGCGTGCGTGCAGCGGGCGTGAACCGGCCCGATGTGTTCCAGCGCACGGGCAACTATCCGGTGC
CGCCCGGTGCCTCGGATATTCCGGGGCTCGAAGTTGCAGGCGAGATAGTCAGCGGTGATCTGGCGCACGCCGACAATCGC
TACGGCCTGAAGGTAGGCGATCGCGTCTGCGCGCTGGTGCAAGGCGGCGGTTATGCGGAGTTCTGCACGGCGCCGTTGGG
CCAGGTGCTGCCTGTGCCGGCCGGCTTGTCCGATGTCGAAGCCGCTGCATTGCCAGAAAACTATTTCACCGTGTGGTCGA
ACGTGTTCGACCGAGGCCTGCTGGGGCGGGGCGCGCACGGCGCCGATGAAACGCTGCTCGTGCAGGGCGGCTCCAGCGGC
ATCGGCACGACGGCGATTCAGATCGCGTCTGCATTGGGTCACCGCGTGTTCGCCACGGCCGGTAGCGCCGAAAAGTGTGA
CGCCTGCGTCGAGCTCGGGGCCACGCGCGCCATCAACTACAAGACCGAGGATTTCGTTGAAATCGTCAAGGCCGAGACAG
GGCGCGGCGCCGATGTGGTGCTCGACATGGTCGGCGGCAGTTATGTCGCGCGCGAAATCGCCTGCACCGCCGACGATGGC
CGCATCGTCCTGATCGCGTTGCTGGGCGGCGCCAAGGCCGAGGTGCCGCTGGGCGACATCCTGCGTCGGCGCATTACCTT
GACGGGCTCGACGCTGCGCCCGCGTCCGGTTGCATTCAAGGCGGCCATCGCGGCCAATCTGTATGAAACGGTCTGGCCGT
TGCTTGCGTCTGTGCGCATCAAGCCGGTCGTCCATGAGGTCATGCCGGCCGCACAGGCCGCGCAGGCGCATGCTTTGATG
GAATCGAGCGCGCATATCGGCAAGATCATGTTGGTTTGGGATTGA

Upstream 100 bases:

>100_bases
TGCGCGAAACCACGCGCGGCATTCCGCAGCACTTTGTTGAACCGAGGCGTAGCGTCTCGTAACCCGCGCACTGCGCCGTA
ACCCTCTCGATCCGATTCTC

Downstream 100 bases:

>100_bases
CGCCAGGACGCCAAAATTGACCCCGTTTTTGACGCCGCGGTAGAATGCTGGGTTTATTTGACAGTCGACCGGGCAAAACG
TGAACGCAAGACCGAAGCTG

Product: NAD(P)H quinone oxidoreductase, PIG3 family

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKAIEITQYGGPEVLKLGERPMPEAKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDIPGLEVAGEIVSGDLAHADNR
YGLKVGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDVEAAALPENYFTVWSNVFDRGLLGRGAHGADETLLVQGGSSG
IGTTAIQIASALGHRVFATAGSAEKCDACVELGATRAINYKTEDFVEIVKAETGRGADVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGDILRRRITLTGSTLRPRPVAFKAAIAANLYETVWPLLASVRIKPVVHEVMPAAQAAQAHALM
ESSAHIGKIMLVWD

Sequences:

>Translated_334_residues
MKAIEITQYGGPEVLKLGERPMPEAKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDIPGLEVAGEIVSGDLAHADNR
YGLKVGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDVEAAALPENYFTVWSNVFDRGLLGRGAHGADETLLVQGGSSG
IGTTAIQIASALGHRVFATAGSAEKCDACVELGATRAINYKTEDFVEIVKAETGRGADVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGDILRRRITLTGSTLRPRPVAFKAAIAANLYETVWPLLASVRIKPVVHEVMPAAQAAQAHALM
ESSAHIGKIMLVWD
>Mature_334_residues
MKAIEITQYGGPEVLKLGERPMPEAKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDIPGLEVAGEIVSGDLAHADNR
YGLKVGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDVEAAALPENYFTVWSNVFDRGLLGRGAHGADETLLVQGGSSG
IGTTAIQIASALGHRVFATAGSAEKCDACVELGATRAINYKTEDFVEIVKAETGRGADVVLDMVGGSYVAREIACTADDG
RIVLIALLGGAKAEVPLGDILRRRITLTGSTLRPRPVAFKAAIAANLYETVWPLLASVRIKPVVHEVMPAAQAAQAHALM
ESSAHIGKIMLVWD

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=37.7581120943953, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=37.7581120943953, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI194239674, Length=340, Percent_Identity=30.5882352941176, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI13236495, Length=340, Percent_Identity=30.5882352941176, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI18379349, Length=349, Percent_Identity=29.512893982808, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI194239676, Length=335, Percent_Identity=29.8507462686567, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=26.9340974212034, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=29.375, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI28557745, Length=274, Percent_Identity=29.5620437956204, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI47519420, Length=243, Percent_Identity=32.9218106995885, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=26.1780104712042, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790485, Length=342, Percent_Identity=30.7017543859649, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17507255, Length=322, Percent_Identity=27.0186335403727, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319520, Length=338, Percent_Identity=26.0355029585799, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323961, Length=307, Percent_Identity=27.3615635179153, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=291, Percent_Identity=24.3986254295533, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323729, Length=291, Percent_Identity=24.0549828178694, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221330659, Length=279, Percent_Identity=27.9569892473118, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI19920632, Length=279, Percent_Identity=27.9569892473118, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=27.6752767527675, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45550423, Length=321, Percent_Identity=24.6105919003115, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34942; Mature: 34942

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEITQYGGPEVLKLGERPMPEAKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDI
CCEEEEECCCCCHHEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVSGDLAHADNRYGLKVGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDVE
CCHHHHHHHHCCCHHCCCCCCCEEECCEEEEEEECCCCHHHHHCCCHHHCCCCCCCCCCH
AAALPENYFTVWSNVFDRGLLGRGAHGADETLLVQGGSSGIGTTAIQIASALGHRVFATA
HHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEC
GSAEKCDACVELGATRAINYKTEDFVEIVKAETGRGADVVLDMVGGSYVAREIACTADDG
CCHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHEEEEECCCC
RIVLIALLGGAKAEVPLGDILRRRITLTGSTLRPRPVAFKAAIAANLYETVWPLLASVRI
CEEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KPVVHEVMPAAQAAQAHALMESSAHIGKIMLVWD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MKAIEITQYGGPEVLKLGERPMPEAKAGEVLIRVRAAGVNRPDVFQRTGNYPVPPGASDI
CCEEEEECCCCCHHEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGEIVSGDLAHADNRYGLKVGDRVCALVQGGGYAEFCTAPLGQVLPVPAGLSDVE
CCHHHHHHHHCCCHHCCCCCCCEEECCEEEEEEECCCCHHHHHCCCHHHCCCCCCCCCCH
AAALPENYFTVWSNVFDRGLLGRGAHGADETLLVQGGSSGIGTTAIQIASALGHRVFATA
HHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEC
GSAEKCDACVELGATRAINYKTEDFVEIVKAETGRGADVVLDMVGGSYVAREIACTADDG
CCHHHHHHHHHCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHEEEEECCCC
RIVLIALLGGAKAEVPLGDILRRRITLTGSTLRPRPVAFKAAIAANLYETVWPLLASVRI
CEEEEEEECCCCCCCCHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KPVVHEVMPAAQAAQAHALMESSAHIGKIMLVWD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]