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The map label for this gene is nahR [H]

Identifier: 187929254

GI number: 187929254

Start: 2287722

End: 2288666

Strand: Reverse

Name: nahR [H]

Synonym: Rpic_2175

Alternate gene names: 187929254

Gene position: 2288666-2287722 (Counterclockwise)

Preceding gene: 187929259

Following gene: 187929252

Centisome position: 58.05

GC content: 68.99

Gene sequence:

>945_bases
ATGCATATATCGCGCGTCGATCTGAACCTGTTCGTCGTCTTCGACGCCATCTATACGGAAGGCGGGATTACCGCGGCCGC
CCGCACGCTCAACCTGACGCAGCCGGCGGTCAGCCACGCCCTGGGGCGGCTGCGCGAACTGTTTGACGACCCGCTGTTCG
AGCGGCGCGGGCAGGGCATGGTGCCGACGCCGCTGGCGCGCACGCTCATTGCGGAGGTCCGCACGGCGCTGCAGGGCTTC
GAGCGCACCCTGCGTGAAGGCACGCGTTTCGACCCCGCCACGAGCGAGCGCCGCTTCACGTTGTCGATGCGCGATGCGCT
GGAAGCGACGTTGCTGCCGCCGCTCATGGCGGCCATCGCCAAGGAGGCGCCGCGCATCGACGTCACGACCGTGCGCGGAG
ACCGCCGCCAGCTCGAAACCGAGTTGCTGGCCGGCACCATCGACGCAGCGGCGGACATTCTGCTGCCGGCATCCCCAGCC
ATCCGGCATGCGCCGCTGCTGACCGATCCGATGGTGGTGCTGGCGCGCCCCGGCCACCCCATCGCGCATGAACCGCTGAC
GCTGGAGCGCTACCTGGCGTGTGAACACGTGCATGTGTCGTCGCGGCGCCGTGGCGCAGGGCTGGAGGATGTGGAGCTGC
GTCGCCTTGGCCACGAGCGGCGCGTGCGGCTGCGTTGCCAGCATTACCCGGCCGCCTGCCGCGTGGTGAGCTGCACGGAC
CTGCTTGCCACGTTGCCGATCCGCTATGCGCGCATTGCCAACGAGCCGTATGGCAACGTGATGCTGCCCCTGCCGTTCAA
CGTGCAGCCGCTTGAGCTGTACCTGTACTGGCACACCAACAGCGACCAGGATGCCGCCAGCCGCTGGCTGCGCGACCACG
TGTTCGCCGCGATGGCGGAGGTCGCCCTGGACGATGCTGTGGCGGCATTCGCCGACGGGCGTTGA

Upstream 100 bases:

>100_bases
TGGTCATGGCGCGTGGCGCAACTCCCAAGTGGTGTCCGCAGAATAAGCCTTCGCCTACAATAAGAGAAATGAATTTCGTA
GATTGCGGTCCATCAATGTC

Downstream 100 bases:

>100_bases
CGAACGGAAAGTCGGACGCAATCATCGGGGTTACGCAGCGCAAATGGCGTAACCACGCCGGTTTATGACAGATTGATAGC
ATTCGGTGTGCCCCGGTTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MHISRVDLNLFVVFDAIYTEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGMVPTPLARTLIAEVRTALQGF
ERTLREGTRFDPATSERRFTLSMRDALEATLLPPLMAAIAKEAPRIDVTTVRGDRRQLETELLAGTIDAAADILLPASPA
IRHAPLLTDPMVVLARPGHPIAHEPLTLERYLACEHVHVSSRRRGAGLEDVELRRLGHERRVRLRCQHYPAACRVVSCTD
LLATLPIRYARIANEPYGNVMLPLPFNVQPLELYLYWHTNSDQDAASRWLRDHVFAAMAEVALDDAVAAFADGR

Sequences:

>Translated_314_residues
MHISRVDLNLFVVFDAIYTEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGMVPTPLARTLIAEVRTALQGF
ERTLREGTRFDPATSERRFTLSMRDALEATLLPPLMAAIAKEAPRIDVTTVRGDRRQLETELLAGTIDAAADILLPASPA
IRHAPLLTDPMVVLARPGHPIAHEPLTLERYLACEHVHVSSRRRGAGLEDVELRRLGHERRVRLRCQHYPAACRVVSCTD
LLATLPIRYARIANEPYGNVMLPLPFNVQPLELYLYWHTNSDQDAASRWLRDHVFAAMAEVALDDAVAAFADGR
>Mature_314_residues
MHISRVDLNLFVVFDAIYTEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGMVPTPLARTLIAEVRTALQGF
ERTLREGTRFDPATSERRFTLSMRDALEATLLPPLMAAIAKEAPRIDVTTVRGDRRQLETELLAGTIDAAADILLPASPA
IRHAPLLTDPMVVLARPGHPIAHEPLTLERYLACEHVHVSSRRRGAGLEDVELRRLGHERRVRLRCQHYPAACRVVSCTD
LLATLPIRYARIANEPYGNVMLPLPFNVQPLELYLYWHTNSDQDAASRWLRDHVFAAMAEVALDDAVAAFADGR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=291, Percent_Identity=31.9587628865979, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI87081766, Length=291, Percent_Identity=26.4604810996564, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=27.8145695364238, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1786820, Length=290, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787601, Length=284, Percent_Identity=22.887323943662, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35013; Mature: 35013

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISRVDLNLFVVFDAIYTEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGM
CCCEEEEEEEEEEEEHHHCCCCCHHHHHEECCCHHHHHHHHHHHHHHHCCHHHHHCCCCC
VPTPLARTLIAEVRTALQGFERTLREGTRFDPATSERRFTLSMRDALEATLLPPLMAAIA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
KEAPRIDVTTVRGDRRQLETELLAGTIDAAADILLPASPAIRHAPLLTDPMVVLARPGHP
HCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEECCCCC
IAHEPLTLERYLACEHVHVSSRRRGAGLEDVELRRLGHERRVRLRCQHYPAACRVVSCTD
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHEEEEECCCCCHHEEHHHHH
LLATLPIRYARIANEPYGNVMLPLPFNVQPLELYLYWHTNSDQDAASRWLRDHVFAAMAE
HHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VALDDAVAAFADGR
HHHHHHHHHHCCCC
>Mature Secondary Structure
MHISRVDLNLFVVFDAIYTEGGITAAARTLNLTQPAVSHALGRLRELFDDPLFERRGQGM
CCCEEEEEEEEEEEEHHHCCCCCHHHHHEECCCHHHHHHHHHHHHHHHCCHHHHHCCCCC
VPTPLARTLIAEVRTALQGFERTLREGTRFDPATSERRFTLSMRDALEATLLPPLMAAIA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
KEAPRIDVTTVRGDRRQLETELLAGTIDAAADILLPASPAIRHAPLLTDPMVVLARPGHP
HCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEECCCCC
IAHEPLTLERYLACEHVHVSSRRRGAGLEDVELRRLGHERRVRLRCQHYPAACRVVSCTD
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHEEEEECCCCCHHEEHHHHH
LLATLPIRYARIANEPYGNVMLPLPFNVQPLELYLYWHTNSDQDAASRWLRDHVFAAMAE
HHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VALDDAVAAFADGR
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]