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The map label for this gene is fnr [H]

Identifier: 187929188

GI number: 187929188

Start: 2224400

End: 2225077

Strand: Direct

Name: fnr [H]

Synonym: Rpic_2109

Alternate gene names: 187929188

Gene position: 2224400-2225077 (Clockwise)

Preceding gene: 187929187

Following gene: 187929195

Centisome position: 56.42

GC content: 62.09

Gene sequence:

>678_bases
ATGCAAGACCCCCTCAATGTGGGCGATCTGCTCAAGCACAGCCCACTGTTCCTGGACTTCGACAACGATGACATTGCCTT
GCTCGCGCGCGACAGCCACGCAGTGCGCGTGTCGCGGCACGACTTCGCGTTTCGCCGTGGCGACCACGCCGATGGCTTCT
ATGTCGTGGTGGTCGGTGCGATCAAACTCGTATTGCCGGGGGCGCACGGCCAATGCAAGGTCATCGAGTTCTTCGGGCCC
GGCGAGTGGTTTGGTGAGCCCTTCATGTTTCTGAACCGCCCCCACGCGGCAGATGCGCAAGCCATGGAAGACAGCCTGCT
TGTCTGGATCGGTAAGCGCGGCGTCGACGATGCACTCCACGTGCATCCGCGCCTGGCGCGGCAGATGTTGACGGGGCTGT
CCACCCGCCTGCACACGCTGATGTGCGACATCGAAACCGTGAACCTGCAAAGCGCCAATGAACGGCTGATCGGGTATTTG
CTCTCGCTGCCGCGCAAGTTTGATCGCACGCGGTTTCCATGCAGCAAGAGTCTGGTCGCGTCCAAGCTTGGGCTGGCACC
GGCCACGCTTTCCCGCACGCTGCGACAGTTGATTCGCGACGGGTTGATCCGCGTGGAAGGCCGCGAGGTCGTGATCCAAA
ACACCACGGCGTTGCAGCGTCAGCTCATCGCGGGATAA

Upstream 100 bases:

>100_bases
TACCGAAGTGCCCCCGGAACCCCGGCCATCACGCTGCCCAGCGAGAGCACTCAGCGCGCATTGGCTGCCAGCTTTTCTTC
TTTCTGTTGCCGGTGACACC

Downstream 100 bases:

>100_bases
CAGTAGAAGCTCGACGCAGGTCAATCGCCTGCGGTGTCGAGCCGATGCTTGAGCGTGTTGACGGCATCATCCACCAGCGC
GGCGGCAGCACTCAATTCAT

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MQDPLNVGDLLKHSPLFLDFDNDDIALLARDSHAVRVSRHDFAFRRGDHADGFYVVVVGAIKLVLPGAHGQCKVIEFFGP
GEWFGEPFMFLNRPHAADAQAMEDSLLVWIGKRGVDDALHVHPRLARQMLTGLSTRLHTLMCDIETVNLQSANERLIGYL
LSLPRKFDRTRFPCSKSLVASKLGLAPATLSRTLRQLIRDGLIRVEGREVVIQNTTALQRQLIAG

Sequences:

>Translated_225_residues
MQDPLNVGDLLKHSPLFLDFDNDDIALLARDSHAVRVSRHDFAFRRGDHADGFYVVVVGAIKLVLPGAHGQCKVIEFFGP
GEWFGEPFMFLNRPHAADAQAMEDSLLVWIGKRGVDDALHVHPRLARQMLTGLSTRLHTLMCDIETVNLQSANERLIGYL
LSLPRKFDRTRFPCSKSLVASKLGLAPATLSRTLRQLIRDGLIRVEGREVVIQNTTALQRQLIAG
>Mature_225_residues
MQDPLNVGDLLKHSPLFLDFDNDDIALLARDSHAVRVSRHDFAFRRGDHADGFYVVVVGAIKLVLPGAHGQCKVIEFFGP
GEWFGEPFMFLNRPHAADAQAMEDSLLVWIGKRGVDDALHVHPRLARQMLTGLSTRLHTLMCDIETVNLQSANERLIGYL
LSLPRKFDRTRFPCSKSLVASKLGLAPATLSRTLRQLIRDGLIRVEGREVVIQNTTALQRQLIAG

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=182, Percent_Identity=26.3736263736264, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 25128; Mature: 25128

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDPLNVGDLLKHSPLFLDFDNDDIALLARDSHAVRVSRHDFAFRRGDHADGFYVVVVGA
CCCCCCHHHHHHCCCEEEEECCCCEEEEEECCCEEEEECCCHHHCCCCCCCCEEEEEEEH
IKLVLPGAHGQCKVIEFFGPGEWFGEPFMFLNRPHAADAQAMEDSLLVWIGKRGVDDALH
HHHEECCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCHHHHCCCEEEEECCCCCCHHHH
VHPRLARQMLTGLSTRLHTLMCDIETVNLQSANERLIGYLLSLPRKFDRTRFPCSKSLVA
CCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCHHHCCCCCCCHHHHHH
SKLGLAPATLSRTLRQLIRDGLIRVEGREVVIQNTTALQRQLIAG
HHHCCCHHHHHHHHHHHHHCCCEEECCCEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MQDPLNVGDLLKHSPLFLDFDNDDIALLARDSHAVRVSRHDFAFRRGDHADGFYVVVVGA
CCCCCCHHHHHHCCCEEEEECCCCEEEEEECCCEEEEECCCHHHCCCCCCCCEEEEEEEH
IKLVLPGAHGQCKVIEFFGPGEWFGEPFMFLNRPHAADAQAMEDSLLVWIGKRGVDDALH
HHHEECCCCCCEEEEEEECCCCCCCCCCCEECCCCCCCHHHHCCCEEEEECCCCCCHHHH
VHPRLARQMLTGLSTRLHTLMCDIETVNLQSANERLIGYLLSLPRKFDRTRFPCSKSLVA
CCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCHHHCCCCCCCHHHHHH
SKLGLAPATLSRTLRQLIRDGLIRVEGREVVIQNTTALQRQLIAG
HHHCCCHHHHHHHHHHHHHCCCEEECCCEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]