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The map label for this gene is nac [H]

Identifier: 187929130

GI number: 187929130

Start: 2161563

End: 2162465

Strand: Reverse

Name: nac [H]

Synonym: Rpic_2051

Alternate gene names: 187929130

Gene position: 2162465-2161563 (Counterclockwise)

Preceding gene: 187929139

Following gene: 187929129

Centisome position: 54.85

GC content: 59.47

Gene sequence:

>903_bases
ATGGATCTCAAGCAAATTCAGTACTTCATCGCGCTTTTCGAAGAAGGCTCTGTCACGCGGGCAGCCAAGCGGTTGAATAT
CGTGCAGCCGGCCCTGAGCATGCAGATAGCCAAGCTCGAGGATGAGTTCGGACAGAAGCTTTTTGAACGCATCCCGCACG
GTATGGCGCCAACTGCCGCTGGCCGGATGATGCACCGACTGTTTCTGCCGATCGTGCGCGATCTCGCGAGTGCCCGGCAG
CAGATGATGCAGCGCGAGGAGCATATGGCCGGCCGCATCACGATCGGCATGGTGGCTTCCGAGACAGAGAGCGTGCTGGT
CGGAGCCCTGGCACGCTTTAACGCGAGCTATCCGAATGTAGAGGTGTCTGTGGCAGATGGCTTCAGCACGGCACTGATCA
ACCTTGTTTCCGCTGGCCAGCTTGATGCAGCGGTGGTCCATCGCCAACGTGGTCGGCTGGCGCTGCAGGTGCAGTCGCTG
CATGACGAAGAGATGGTGCTAGTGACGAGCGTCGCAAATGGCCCTGAATTGCCGGAATCGGTGGAAATGGCGAAGCTGCC
TGGACTGGAGCTTGTGTTACCGACGAAGTCGCACGGCCTACGCGTGGTATTGGATACTGCCACGCAGGCGCACGACGTCA
CGCTGGCGCCAAAGTTCGAAATTGACATCCTTGGGACCATCGTGCAGTTCGTTGAAGCTACGCGTTTCGCCACTGTGTTG
CCGCGCATCGTGGTGCAGCGTGCCGTGGAAGAGGGACGGCTGCGCATGCATACCATTGTTGCGCCGCGCATCGTGCGGCA
TCTGGTCTGCGTCAGCCATCCTCAGCGGCCGTTAAGCACGGCAACCGAGGCGTTGATTGCAATCGTGACCGAAGAAATCA
AGCGCGTTTCGGGGATGGCGTAG

Upstream 100 bases:

>100_bases
CGCTGTGTCTCATAATTGATGGCATGGGGTGCCATGACCATCGTCGCAGGGACCGCAAAGATTGATGCCGCCACACGGTA
CCGTTCATACCCATCCGAAT

Downstream 100 bases:

>100_bases
CGCAGTGGGGGCCGATGCGCGGCGCATTCGGCTACGGGGGCGTGCTCCGGCAGAAATGATGTGTCGTGAGCCATGTGTTC
GGTCGCTTCCGTCGGCGGAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen assimilation control protein [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDLKQIQYFIALFEEGSVTRAAKRLNIVQPALSMQIAKLEDEFGQKLFERIPHGMAPTAAGRMMHRLFLPIVRDLASARQ
QMMQREEHMAGRITIGMVASETESVLVGALARFNASYPNVEVSVADGFSTALINLVSAGQLDAAVVHRQRGRLALQVQSL
HDEEMVLVTSVANGPELPESVEMAKLPGLELVLPTKSHGLRVVLDTATQAHDVTLAPKFEIDILGTIVQFVEATRFATVL
PRIVVQRAVEEGRLRMHTIVAPRIVRHLVCVSHPQRPLSTATEALIAIVTEEIKRVSGMA

Sequences:

>Translated_300_residues
MDLKQIQYFIALFEEGSVTRAAKRLNIVQPALSMQIAKLEDEFGQKLFERIPHGMAPTAAGRMMHRLFLPIVRDLASARQ
QMMQREEHMAGRITIGMVASETESVLVGALARFNASYPNVEVSVADGFSTALINLVSAGQLDAAVVHRQRGRLALQVQSL
HDEEMVLVTSVANGPELPESVEMAKLPGLELVLPTKSHGLRVVLDTATQAHDVTLAPKFEIDILGTIVQFVEATRFATVL
PRIVVQRAVEEGRLRMHTIVAPRIVRHLVCVSHPQRPLSTATEALIAIVTEEIKRVSGMA
>Mature_300_residues
MDLKQIQYFIALFEEGSVTRAAKRLNIVQPALSMQIAKLEDEFGQKLFERIPHGMAPTAAGRMMHRLFLPIVRDLASARQ
QMMQREEHMAGRITIGMVASETESVLVGALARFNASYPNVEVSVADGFSTALINLVSAGQLDAAVVHRQRGRLALQVQSL
HDEEMVLVTSVANGPELPESVEMAKLPGLELVLPTKSHGLRVVLDTATQAHDVTLAPKFEIDILGTIVQFVEATRFATVL
PRIVVQRAVEEGRLRMHTIVAPRIVRHLVCVSHPQRPLSTATEALIAIVTEEIKRVSGMA

Specific function: Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=26.7489711934156, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=32.8859060402685, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790399, Length=285, Percent_Identity=25.6140350877193, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=292, Percent_Identity=25, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI157672245, Length=295, Percent_Identity=22.3728813559322, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=22.7586206896552, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=24.9134948096886, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367136, Length=148, Percent_Identity=34.4594594594595, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789506, Length=235, Percent_Identity=25.1063829787234, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787806, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787589, Length=263, Percent_Identity=23.9543726235741, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787879, Length=150, Percent_Identity=32.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=302, Percent_Identity=23.5099337748344, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788887, Length=195, Percent_Identity=27.1794871794872, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32971; Mature: 32971

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKQIQYFIALFEEGSVTRAAKRLNIVQPALSMQIAKLEDEFGQKLFERIPHGMAPTAA
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
GRMMHRLFLPIVRDLASARQQMMQREEHMAGRITIGMVASETESVLVGALARFNASYPNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCE
EVSVADGFSTALINLVSAGQLDAAVVHRQRGRLALQVQSLHDEEMVLVTSVANGPELPES
EEEECCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCH
VEMAKLPGLELVLPTKSHGLRVVLDTATQAHDVTLAPKFEIDILGTIVQFVEATRFATVL
HHHHHCCCCEEEECCCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
PRIVVQRAVEEGRLRMHTIVAPRIVRHLVCVSHPQRPLSTATEALIAIVTEEIKRVSGMA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLKQIQYFIALFEEGSVTRAAKRLNIVQPALSMQIAKLEDEFGQKLFERIPHGMAPTAA
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
GRMMHRLFLPIVRDLASARQQMMQREEHMAGRITIGMVASETESVLVGALARFNASYPNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCE
EVSVADGFSTALINLVSAGQLDAAVVHRQRGRLALQVQSLHDEEMVLVTSVANGPELPES
EEEECCCHHHHHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCH
VEMAKLPGLELVLPTKSHGLRVVLDTATQAHDVTLAPKFEIDILGTIVQFVEATRFATVL
HHHHHCCCCEEEECCCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHH
PRIVVQRAVEEGRLRMHTIVAPRIVRHLVCVSHPQRPLSTATEALIAIVTEEIKRVSGMA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8458853 [H]