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The map label for this gene is aroC

Identifier: 187929067

GI number: 187929067

Start: 2096771

End: 2097871

Strand: Reverse

Name: aroC

Synonym: Rpic_1987

Alternate gene names: 187929067

Gene position: 2097871-2096771 (Counterclockwise)

Preceding gene: 187929068

Following gene: 187929065

Centisome position: 53.21

GC content: 62.94

Gene sequence:

>1101_bases
ATGTCTGGCAATACCTTGGGCCTGCTGTTTTCCGTCACCACTTTCGGCGAGTCGCATGGCCCGGCCATCGGCGCTGTCAT
CGACGGCTGCCCACCCGGCATGACGCTATCGGCAGAAGACATCCAGCCCGATCTGGATCGCCGCAAGCCCGGCACCTCGC
GGCACGTGACGCAGCGCAAGGAGGAAGACCTTGTTGAGATCCTCTCCGGCGTGTACGAAGGCAAGACCACGGGCACCCCG
ATTTGTCTGCTGATCCGCAACACAGATCAGCGCAGCAAGGACTACAGCAACATCGCCGAGACATTCCGTCCCGGCCATGC
CGATTACACGTACTGGCACAAATACGGCATCCGTGACCCGCGTGGTGGTGGCCGTTCTTCCGCACGATTGACGGCGCCGA
CGGTGGCCGCAGGTGCTGTCGCCAAGAAGTGGCTGCGTGAGAAGTTCGGCATCGAAATCCACGGCTTCATGTCGCAACTG
GGCGATATCCACATTCCGTTCATGGACTGGAACGAGGTGCCGAACAACCCGTTCTTCGCGCCCAATGCCGAGATCGTTCC
CGAGCTGGAAACCTACATGGATGCACTGCGCAAAGATGGCGATTCCGTCGGCGCGCGCATTGAAGTGGTGGCCACGGGCG
TGCCCGTCGGTTGGGGCGAGCCGCTGTTCGATCGCCTGGATGCAGACATTGCCCACGCCATGATGGGTCTGAACGCAGTC
AAGGGCGTTGAGATCGGTGCAGGCTTCCACGCGGTCAGCCAGCGCGGTTCCGAGCATGGTGATGAGCTGACGCCGGAGGG
CTTCGTCGGCAACAACGCCGGCGGTATCCTGGGTGGGATTTCGACGGGGCAGGATATCTCTGTGTCGCTGGCGATCAAGC
CGACGTCGAGCATCCGCACGCCGCGCCGTTCGATCGACAAGGCGGGTGACCCGGCGGTGGTGGAAACGTTCGGCCGCCAT
GATCCATGCGTGGGCATTCGTGCCACGCCGATCGCCGAGGCGCTGCTGGCGCTGGTGCTGATCGACCACGCGCTGCGTCA
TCGTGCGCAATGTGGCGATGTGTCCGTGGAGACGCCGGCCATTCCGGCAAAAGCTTCCTGA

Upstream 100 bases:

>100_bases
GGTATCGGTGGCTGATCTGGAGGCCGGTGGATCGGCCTTACAATAGCGTTTTCCTGATGTTTCGCGCCGCGGCCGTCGCG
GCGCCTTCCTGAGCACGATC

Downstream 100 bases:

>100_bases
ATCGATTTGCGCAGACAACAAAAAAGACGGCTTCAAGCCGTCTTTTTTGTTGGGCGACCGCCCGGTGCTTACATGCCGAC
GTAGTTCGGCCCGCCACCGC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMTLSAEDIQPDLDRRKPGTSRHVTQRKEEDLVEILSGVYEGKTTGTP
ICLLIRNTDQRSKDYSNIAETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPTVAAGAVAKKWLREKFGIEIHGFMSQL
GDIHIPFMDWNEVPNNPFFAPNAEIVPELETYMDALRKDGDSVGARIEVVATGVPVGWGEPLFDRLDADIAHAMMGLNAV
KGVEIGAGFHAVSQRGSEHGDELTPEGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRTPRRSIDKAGDPAVVETFGRH
DPCVGIRATPIAEALLALVLIDHALRHRAQCGDVSVETPAIPAKAS

Sequences:

>Translated_366_residues
MSGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMTLSAEDIQPDLDRRKPGTSRHVTQRKEEDLVEILSGVYEGKTTGTP
ICLLIRNTDQRSKDYSNIAETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPTVAAGAVAKKWLREKFGIEIHGFMSQL
GDIHIPFMDWNEVPNNPFFAPNAEIVPELETYMDALRKDGDSVGARIEVVATGVPVGWGEPLFDRLDADIAHAMMGLNAV
KGVEIGAGFHAVSQRGSEHGDELTPEGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRTPRRSIDKAGDPAVVETFGRH
DPCVGIRATPIAEALLALVLIDHALRHRAQCGDVSVETPAIPAKAS
>Mature_365_residues
SGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMTLSAEDIQPDLDRRKPGTSRHVTQRKEEDLVEILSGVYEGKTTGTPI
CLLIRNTDQRSKDYSNIAETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPTVAAGAVAKKWLREKFGIEIHGFMSQLG
DIHIPFMDWNEVPNNPFFAPNAEIVPELETYMDALRKDGDSVGARIEVVATGVPVGWGEPLFDRLDADIAHAMMGLNAVK
GVEIGAGFHAVSQRGSEHGDELTPEGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRTPRRSIDKAGDPAVVETFGRHD
PCVGIRATPIAEALLALVLIDHALRHRAQCGDVSVETPAIPAKAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=63.7883008356546, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=42.2764227642276, Blast_Score=289, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_RALPJ (B2UGK8)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001899554.1
- ProteinModelPortal:   B2UGK8
- SMR:   B2UGK8
- GeneID:   6289809
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_1987
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39090; Mature: 38958

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMTLSAEDIQPDLDRRKPGTSRHVTQRK
CCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCEEEHHHCCCCHHHCCCCCCHHHHHHH
EEDLVEILSGVYEGKTTGTPICLLIRNTDQRSKDYSNIAETFRPGHADYTYWHKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCC
RGGGRSSARLTAPTVAAGAVAKKWLREKFGIEIHGFMSQLGDIHIPFMDWNEVPNNPFFA
CCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCCCCCCCCCCCC
PNAEIVPELETYMDALRKDGDSVGARIEVVATGVPVGWGEPLFDRLDADIAHAMMGLNAV
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFHAVSQRGSEHGDELTPEGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRT
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHHCC
PRRSIDKAGDPAVVETFGRHDPCVGIRATPIAEALLALVLIDHALRHRAQCGDVSVETPA
CHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
IPAKAS
CCCCCC
>Mature Secondary Structure 
SGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMTLSAEDIQPDLDRRKPGTSRHVTQRK
CCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCEEEHHHCCCCHHHCCCCCCHHHHHHH
EEDLVEILSGVYEGKTTGTPICLLIRNTDQRSKDYSNIAETFRPGHADYTYWHKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCC
RGGGRSSARLTAPTVAAGAVAKKWLREKFGIEIHGFMSQLGDIHIPFMDWNEVPNNPFFA
CCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCCCCCCCCCCCC
PNAEIVPELETYMDALRKDGDSVGARIEVVATGVPVGWGEPLFDRLDADIAHAMMGLNAV
CCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFHAVSQRGSEHGDELTPEGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRT
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHHCC
PRRSIDKAGDPAVVETFGRHDPCVGIRATPIAEALLALVLIDHALRHRAQCGDVSVETPA
CHHHHHCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
IPAKAS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA