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The map label for this gene is dctS [H]

Identifier: 187929028

GI number: 187929028

Start: 2057190

End: 2059766

Strand: Direct

Name: dctS [H]

Synonym: Rpic_1948

Alternate gene names: 187929028

Gene position: 2057190-2059766 (Clockwise)

Preceding gene: 187929023

Following gene: 187929029

Centisome position: 52.18

GC content: 64.88

Gene sequence:

>2577_bases
ATGTCCACTCCTTTACCTCCGCAGAATTCCGGCGTTCGTCCGCCCATCATGCTTGCCCCCTCCCACGCTTCGCAGGACCC
GGCCGCCAAGTCCGAGCCGTCAACGCCTGCGGCGCCTGCGCCCATTTCCGTGAACGCGTCCGAACAGCCGTCGGACGAGG
CCGTTCGCCCGAACATGCCCCGCCGCCTGTGGCTGACCCGCCTGGGCCGGCTGTGGACGACCAACTGGTTCATGTTCATC
CCGCTGGTGGCAATCGTCCTGTTTGCTGGCGCGATGATTTTCATCCTGTATCAATTGCACGCCACGGAGGTGCAGCAGCA
GCGCGACGCCCTCTACCGCGATGCCGCCTGGGCCGAGCAGAAGGTTCGCCTGTCCCTGCAGAGCAACCAGGATCAGGTGG
CCGCCCTGGCACGCGACATCGGTGCTGCGCAGCTTGACCCGAGCGCCTATCGCGATGCCGCCCGCCAGCTCCTGCGCGAG
AACCCGGAGCTTGTCTTCATCAACTGGCTGGATGCCACGCGCCGCCCGCGCTGGGCGTTCCCGTCCACCTCCGAATTCAC
GGCGCGCGTGCGCGAAACACGCGACCATCCGCTCGAACCCGAAATCCAATCTGCCTACGATGCCGCGCGTGAAACGCAGC
GTGCCGTCTATTCGCGCCCCATCCAGAACGAGCGCGGCGAGAGCTTCATGCTGATGGAAGTCCCGATCGTGCGCGACAAC
GAATTCCTCGGCACGGTGGGCGCCATGTATTCGGTCACGGGCATCCTCACGCAACTGCTGCCGGGCGAGTTGACAGACCG
CTACCGCTTCTCGCTGGTCGACAAGAACAACGTGGTCCGCGCAAGCACGTCGTTGCGGCCGGTGCCCAAGGCGGCGGCGT
CGTACGAGGTGCTGCTCGACCCACCGGGACATTCGCTCTCGCTGCGGGCCGAGGCGTATCCCGCTCCGTCCAACCTGCCC
AACAACATGCTGATGTGGCTGGTGGCCGGCCTGTCGTGCTTCGTGATCTGGAGCCTCTGGAGCGTGTGGCGCCACACCAG
CCGCCGCTCTGAAGCGCAGCGCGCGTTGCTGGCGGAAACGTCGTTCCGCCGCGCTATGGAAAACTCCATGGTGATCGGCA
TGCGTTCGCTCGACCTCAACGGCCGCATCACCTACGTGAACCCGGCGTTCTGCCGCATGATCGGCTGGACGGAAGCCGAG
CTGGTCGGGCGCATGCCGCCCTTCCCGTATTGGCCGCCCAATGAGATCGGCGAGATGCAGAAGCACATCGAGCTGACCTT
GCGTGGCAAGGCGCCCGCCAACGGCATGGAATTGCGCATGATGCGCCGCGACGGTACGAGCTTCTATGCGCGGATGTACG
TCTCGCCGCTGATCGATGCGCGCGGCCGGCACACGGGGTGGATGAGTTCCATCACGGACATTACTGAGCCCAAACGCGCC
CGTGAAGACTTGGCCGCCGCGCACGACCGCTTCACCACGGTGCTGGAGAGCCTGGATGCGGCCGTGTCCGTGCTCTCGAC
CGACAAGGCGGAGCTGCTGTTCGCCAACCGCTACTACCGCCAGCTTTTCGGCTGGGAGGCGTTCGGCCACCTGCAGCTCT
CCGGCAACGACGTCAACACGGAAGACGTTTCCAGCGATGCACTCGACCTGGTGGACGCCTACGCCGGCCTGCCCGCGTCC
GAGTTGACACCGCACGCGGCAGATGCGCGCGAAATCTATGTGCCATCGATGCAGAAGTGGTTTGAAGTGCGGCGCCGCTA
CATCCAGTGGGTCGACGGCCACCTCGCACAGATGCAGATCGCCACCGACATCACCGTGCGCAAGGCCGCCGAAGAGATGA
CGCGCCAGCACGAAGAGCGCCTGCAGTTCACCAGCCGCCTGACGACGATGGGCGAGATGGCCTCATCGCTGGCGCACGAG
CTGAACCAGCCGCTGGCTGCCATCAACAACTACTGCATGGGCGCCGTCGGCCGCCTGAAGAGCGGACGCAGCACGCCGGA
AGAGCTGATCCCGGTGCTTGAGAAGACCTCCGCCCAGGCCGTGCGTGCCGGCACCATCATCCAGCGCATCCGCGGCTTCG
TGAAACGCAGCCAGCCGCAGCGGCGCGAATCCGACCTGCGCGAGATCGTTGCCGACGCCGTGGGTCTGGCCGAACTCGAA
GCCACGCGGCGCGGCATCACCATTCTCACGCGCCTGCCAGGCGACTTGCCGCATCTGTATGTCGATCCGGTGCTCATCGA
GCAGGTGCTCGTCAATCTGCTCAAGAACGCCGCCGAAGCCATGGCCGCCCACCCGCGCCTGCGCGCCGCCAGCGTGCTGC
GCCTGCACGCCAACCTGATCAACGACCCGGAAAATTCCGTGCTGATCGAGGTGATCGACCAGGGCCCGGGCGTGGACGAC
AGCACTAAGGAGCGGCTGTTCGAGCCGTTCTTCAGTACAAAATCCGACGGCATGGGTATGGGACTGAATATCTGCCGCTC
CATCATAGAATCCCACCTCGGCAGGCTCTGGGTAGAAAACAACGCCGATGGCATCGGCTGTACGTTTAAAATCATCTTGC
CGCTGAATCCGCTGTAA

Upstream 100 bases:

>100_bases
GCGCAGCATTTTCCGAGCGAACAAGACACCTCACCAAGCGGTTTCCCCAAGCGACCCGCAGGTTGATTGCCGTTACACTT
AGTTTTGCGCAGTTGCACAG

Downstream 100 bases:

>100_bases
ATCGTTTTTAAAACATAGAACGTAGACCGAGGACTCCTCCATGAGCACAACGCCCGCCGCAGTTGCGCCGCGCAACGAAA
CCGTGTTCGTCGTCGATGAC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 858; Mature: 857

Protein sequence:

>858_residues
MSTPLPPQNSGVRPPIMLAPSHASQDPAAKSEPSTPAAPAPISVNASEQPSDEAVRPNMPRRLWLTRLGRLWTTNWFMFI
PLVAIVLFAGAMIFILYQLHATEVQQQRDALYRDAAWAEQKVRLSLQSNQDQVAALARDIGAAQLDPSAYRDAARQLLRE
NPELVFINWLDATRRPRWAFPSTSEFTARVRETRDHPLEPEIQSAYDAARETQRAVYSRPIQNERGESFMLMEVPIVRDN
EFLGTVGAMYSVTGILTQLLPGELTDRYRFSLVDKNNVVRASTSLRPVPKAAASYEVLLDPPGHSLSLRAEAYPAPSNLP
NNMLMWLVAGLSCFVIWSLWSVWRHTSRRSEAQRALLAETSFRRAMENSMVIGMRSLDLNGRITYVNPAFCRMIGWTEAE
LVGRMPPFPYWPPNEIGEMQKHIELTLRGKAPANGMELRMMRRDGTSFYARMYVSPLIDARGRHTGWMSSITDITEPKRA
REDLAAAHDRFTTVLESLDAAVSVLSTDKAELLFANRYYRQLFGWEAFGHLQLSGNDVNTEDVSSDALDLVDAYAGLPAS
ELTPHAADAREIYVPSMQKWFEVRRRYIQWVDGHLAQMQIATDITVRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHE
LNQPLAAINNYCMGAVGRLKSGRSTPEELIPVLEKTSAQAVRAGTIIQRIRGFVKRSQPQRRESDLREIVADAVGLAELE
ATRRGITILTRLPGDLPHLYVDPVLIEQVLVNLLKNAAEAMAAHPRLRAASVLRLHANLINDPENSVLIEVIDQGPGVDD
STKERLFEPFFSTKSDGMGMGLNICRSIIESHLGRLWVENNADGIGCTFKIILPLNPL

Sequences:

>Translated_858_residues
MSTPLPPQNSGVRPPIMLAPSHASQDPAAKSEPSTPAAPAPISVNASEQPSDEAVRPNMPRRLWLTRLGRLWTTNWFMFI
PLVAIVLFAGAMIFILYQLHATEVQQQRDALYRDAAWAEQKVRLSLQSNQDQVAALARDIGAAQLDPSAYRDAARQLLRE
NPELVFINWLDATRRPRWAFPSTSEFTARVRETRDHPLEPEIQSAYDAARETQRAVYSRPIQNERGESFMLMEVPIVRDN
EFLGTVGAMYSVTGILTQLLPGELTDRYRFSLVDKNNVVRASTSLRPVPKAAASYEVLLDPPGHSLSLRAEAYPAPSNLP
NNMLMWLVAGLSCFVIWSLWSVWRHTSRRSEAQRALLAETSFRRAMENSMVIGMRSLDLNGRITYVNPAFCRMIGWTEAE
LVGRMPPFPYWPPNEIGEMQKHIELTLRGKAPANGMELRMMRRDGTSFYARMYVSPLIDARGRHTGWMSSITDITEPKRA
REDLAAAHDRFTTVLESLDAAVSVLSTDKAELLFANRYYRQLFGWEAFGHLQLSGNDVNTEDVSSDALDLVDAYAGLPAS
ELTPHAADAREIYVPSMQKWFEVRRRYIQWVDGHLAQMQIATDITVRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHE
LNQPLAAINNYCMGAVGRLKSGRSTPEELIPVLEKTSAQAVRAGTIIQRIRGFVKRSQPQRRESDLREIVADAVGLAELE
ATRRGITILTRLPGDLPHLYVDPVLIEQVLVNLLKNAAEAMAAHPRLRAASVLRLHANLINDPENSVLIEVIDQGPGVDD
STKERLFEPFFSTKSDGMGMGLNICRSIIESHLGRLWVENNADGIGCTFKIILPLNPL
>Mature_857_residues
STPLPPQNSGVRPPIMLAPSHASQDPAAKSEPSTPAAPAPISVNASEQPSDEAVRPNMPRRLWLTRLGRLWTTNWFMFIP
LVAIVLFAGAMIFILYQLHATEVQQQRDALYRDAAWAEQKVRLSLQSNQDQVAALARDIGAAQLDPSAYRDAARQLLREN
PELVFINWLDATRRPRWAFPSTSEFTARVRETRDHPLEPEIQSAYDAARETQRAVYSRPIQNERGESFMLMEVPIVRDNE
FLGTVGAMYSVTGILTQLLPGELTDRYRFSLVDKNNVVRASTSLRPVPKAAASYEVLLDPPGHSLSLRAEAYPAPSNLPN
NMLMWLVAGLSCFVIWSLWSVWRHTSRRSEAQRALLAETSFRRAMENSMVIGMRSLDLNGRITYVNPAFCRMIGWTEAEL
VGRMPPFPYWPPNEIGEMQKHIELTLRGKAPANGMELRMMRRDGTSFYARMYVSPLIDARGRHTGWMSSITDITEPKRAR
EDLAAAHDRFTTVLESLDAAVSVLSTDKAELLFANRYYRQLFGWEAFGHLQLSGNDVNTEDVSSDALDLVDAYAGLPASE
LTPHAADAREIYVPSMQKWFEVRRRYIQWVDGHLAQMQIATDITVRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHEL
NQPLAAINNYCMGAVGRLKSGRSTPEELIPVLEKTSAQAVRAGTIIQRIRGFVKRSQPQRRESDLREIVADAVGLAELEA
TRRGITILTRLPGDLPHLYVDPVLIEQVLVNLLKNAAEAMAAHPRLRAASVLRLHANLINDPENSVLIEVIDQGPGVDDS
TKERLFEPFFSTKSDGMGMGLNICRSIIESHLGRLWVENNADGIGCTFKIILPLNPL

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=305, Percent_Identity=27.8688524590164, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1790436, Length=239, Percent_Identity=26.7782426778243, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=28.6324786324786, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=25.6302521008403, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786912, Length=127, Percent_Identity=31.496062992126, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 96230; Mature: 96099

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLPPQNSGVRPPIMLAPSHASQDPAAKSEPSTPAAPAPISVNASEQPSDEAVRPNMP
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
RRLWLTRLGRLWTTNWFMFIPLVAIVLFAGAMIFILYQLHATEVQQQRDALYRDAAWAEQ
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVRLSLQSNQDQVAALARDIGAAQLDPSAYRDAARQLLRENPELVFINWLDATRRPRWAF
HHEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
PSTSEFTARVRETRDHPLEPEIQSAYDAARETQRAVYSRPIQNERGESFMLMEVPIVRDN
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECEEECC
EFLGTVGAMYSVTGILTQLLPGELTDRYRFSLVDKNNVVRASTSLRPVPKAAASYEVLLD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEC
PPGHSLSLRAEAYPAPSNLPNNMLMWLVAGLSCFVIWSLWSVWRHTSRRSEAQRALLAET
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFRRAMENSMVIGMRSLDLNGRITYVNPAFCRMIGWTEAELVGRMPPFPYWPPNEIGEMQ
HHHHHHHCCEEEEEEEECCCCEEEEECHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHH
KHIELTLRGKAPANGMELRMMRRDGTSFYARMYVSPLIDARGRHTGWMSSITDITEPKRA
HHEEEEEECCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHH
REDLAAAHDRFTTVLESLDAAVSVLSTDKAELLFANRYYRQLFGWEAFGHLQLSGNDVNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
EDVSSDALDLVDAYAGLPASELTPHAADAREIYVPSMQKWFEVRRRYIQWVDGHLAQMQI
HHCCHHHHHHHHHHHCCCHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCHHHHHHH
ATDITVRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHELNQPLAAINNYCMGAVGRLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
SGRSTPEELIPVLEKTSAQAVRAGTIIQRIRGFVKRSQPQRRESDLREIVADAVGLAELE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ATRRGITILTRLPGDLPHLYVDPVLIEQVLVNLLKNAAEAMAAHPRLRAASVLRLHANLI
HHHCCCEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NDPENSVLIEVIDQGPGVDDSTKERLFEPFFSTKSDGMGMGLNICRSIIESHLGRLWVEN
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEECC
NADGIGCTFKIILPLNPL
CCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
STPLPPQNSGVRPPIMLAPSHASQDPAAKSEPSTPAAPAPISVNASEQPSDEAVRPNMP
CCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
RRLWLTRLGRLWTTNWFMFIPLVAIVLFAGAMIFILYQLHATEVQQQRDALYRDAAWAEQ
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVRLSLQSNQDQVAALARDIGAAQLDPSAYRDAARQLLRENPELVFINWLDATRRPRWAF
HHEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
PSTSEFTARVRETRDHPLEPEIQSAYDAARETQRAVYSRPIQNERGESFMLMEVPIVRDN
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECEEECC
EFLGTVGAMYSVTGILTQLLPGELTDRYRFSLVDKNNVVRASTSLRPVPKAAASYEVLLD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEC
PPGHSLSLRAEAYPAPSNLPNNMLMWLVAGLSCFVIWSLWSVWRHTSRRSEAQRALLAET
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFRRAMENSMVIGMRSLDLNGRITYVNPAFCRMIGWTEAELVGRMPPFPYWPPNEIGEMQ
HHHHHHHCCEEEEEEEECCCCEEEEECHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHH
KHIELTLRGKAPANGMELRMMRRDGTSFYARMYVSPLIDARGRHTGWMSSITDITEPKRA
HHEEEEEECCCCCCCCEEEEEHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHH
REDLAAAHDRFTTVLESLDAAVSVLSTDKAELLFANRYYRQLFGWEAFGHLQLSGNDVNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
EDVSSDALDLVDAYAGLPASELTPHAADAREIYVPSMQKWFEVRRRYIQWVDGHLAQMQI
HHCCHHHHHHHHHHHCCCHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCHHHHHHH
ATDITVRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHELNQPLAAINNYCMGAVGRLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
SGRSTPEELIPVLEKTSAQAVRAGTIIQRIRGFVKRSQPQRRESDLREIVADAVGLAELE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ATRRGITILTRLPGDLPHLYVDPVLIEQVLVNLLKNAAEAMAAHPRLRAASVLRLHANLI
HHHCCCEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NDPENSVLIEVIDQGPGVDDSTKERLFEPFFSTKSDGMGMGLNICRSIIESHLGRLWVEN
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCEEECC
NADGIGCTFKIILPLNPL
CCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]