BacMap

Definition	Ralstonia pickettii 12J chromosome chromosome 1, complete sequence.
Accession	NC_010682
Length	3,942,557

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The map label for this gene is phbB [H]

Identifier: 187928994

GI number: 187928994

Start: 2019045

End: 2019785

Strand: Reverse

Name: phbB [H]

Synonym: Rpic_1914

Alternate gene names: 187928994

Gene position: 2019785-2019045 (Counterclockwise)

Preceding gene: 187928995

Following gene: 187928993

Centisome position: 51.23

GC content: 61.27

Gene sequence:

>741_bases
ATGACCAAACGCATCGCATACGTCACCGGCGGCATGGGCGGTATCGGAACGGCGATTTGCCAGCGCTTGGCGCGCGACGG
CTTCACTGTTGTCGCAGGCTGCGGCCCGAACTCGCCGCGTAAGGCGAAATGGCTCGAACAACAAAAGGCGCTCGGTTTCG
ATTTCGTGCCGTCCGAAGGGAACGTCGGTGACTGGGAGTCGACCAAGGCCGCGTTCGACAAGGTCAAGGCCGAAGTGGGC
GAGGTGGATGTCCTGATCAACAACGCCGGCATTACGCGCGACGTGGTGTTCCGCAAGATGACCCGCGCCGACTGGGATGC
GGTGATCGATACCAACCTGACGTCGCTGTTCAACGTGACGAAGCAGGTCATCGACGGCATGGCGGATCGCGGCTGGGGTC
GAATCATCAACATCTCGTCGGTGAACGGCCAGAAGGGGCAGTTTGGCCAGACCAACTACTCGACCGCCAAGGCTGGCTTG
CATGGTTTCACCATGGCGCTGGCGCAGGAAGTCGCTACCAAGGGCGTGACGGTCAACACCGTGTCGCCGGGCTATATCGC
CACCGACATGGTGAAAGCGATTCGTCAGGATGTGCTCGACAAGATTATTGGCACGATCCCGGTCAAGCGGTTGGGCGAGC
CGACCGAGATTGCCTCGATCTGCGCATGGCTTGCATCGGAAGAGTCCGGCTTCTCCACCGGTGCGGACTTCTCCCTCAAC
GGCGGCCTGCACATGGGCTGA

Upstream 100 bases:

>100_bases
TGAATCGGAACGAATGCCTGACGCGCCAATCCGAGACACCTGAGCATTTGCCGCCCGGCAAGAGGCCGGGCGATTCTAAC
AACAAGGACTAGGAGTGGAC

Downstream 100 bases:

>100_bases
CGCTCCCACGCCTGTGCTGCGGCGATGCTGCAGCACAGGCGCAGCAATTTTTCCCCTGATTTGCCTGCATGCTGCGATGC
TTGAGTGCATTGCAGCAGGC

Product: acetyacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTKRIAYVTGGMGGIGTAICQRLARDGFTVVAGCGPNSPRKAKWLEQQKALGFDFVPSEGNVGDWESTKAAFDKVKAEVG
EVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMADRGWGRIINISSVNGQKGQFGQTNYSTAKAGL
HGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGEPTEIASICAWLASEESGFSTGADFSLN
GGLHMG

Sequences:

>Translated_246_residues
MTKRIAYVTGGMGGIGTAICQRLARDGFTVVAGCGPNSPRKAKWLEQQKALGFDFVPSEGNVGDWESTKAAFDKVKAEVG
EVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMADRGWGRIINISSVNGQKGQFGQTNYSTAKAGL
HGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGEPTEIASICAWLASEESGFSTGADFSLN
GGLHMG
>Mature_245_residues
TKRIAYVTGGMGGIGTAICQRLARDGFTVVAGCGPNSPRKAKWLEQQKALGFDFVPSEGNVGDWESTKAAFDKVKAEVGE
VDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMADRGWGRIINISSVNGQKGQFGQTNYSTAKAGLH
GFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGEPTEIASICAWLASEESGFSTGADFSLNG
GLHMG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=38, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=34.5528455284553, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=32.6771653543307, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.1204819277108, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=31.7073170731707, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI83715985, Length=254, Percent_Identity=31.1023622047244, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=29.8387096774194, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=29.2181069958848, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=29.6442687747036, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.9595141700405, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=29.8387096774194, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=183, Percent_Identity=30.0546448087432, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=25.5230125523013, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=246, Percent_Identity=29.6747967479675, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=30.622009569378, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.6116504854369, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=179, Percent_Identity=30.7262569832402, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI7657478, Length=208, Percent_Identity=29.3269230769231, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=26.3681592039801, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI40548397, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010158, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI214010156, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI22758144, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150247226, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=27.8350515463918, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19743808, Length=193, Percent_Identity=29.0155440414508, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4557649, Length=230, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=42.914979757085, Blast_Score=194, Evalue=3e-51,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=35.8565737051793, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789208, Length=242, Percent_Identity=30.9917355371901, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=31.4285714285714, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.0983606557377, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=29.9180327868852, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=31.3008130081301, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=28, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=27.5, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=26.4705882352941, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=29.5081967213115, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=29.4416243654822, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=247, Percent_Identity=40.4858299595142, Blast_Score=161, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=36.1788617886179, Blast_Score=153, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30.4, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17568967, Length=249, Percent_Identity=33.7349397590361, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.496062992126, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=30.4, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.5546558704453, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=28.6885245901639, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.9595141700405, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.8625954198473, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=28.6852589641434, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=200, Percent_Identity=28, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=28, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=28.4615384615385, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=28.4132841328413, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=155, Percent_Identity=32.9032258064516, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=30.2083333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.6259541984733, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=26.9662921348315, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.6259541984733, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=28.3524904214559, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=26.4925373134328, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=276, Percent_Identity=26.4492753623188, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=24.0458015267176, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=251, Percent_Identity=29.4820717131474, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=27.1062271062271, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=243, Percent_Identity=26.7489711934156, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=32.6612903225806, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=25.8706467661692, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=34.9593495934959, Blast_Score=133, Evalue=9e-32,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=34.6613545816733, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=31.5573770491803, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=32.8, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=29.7619047619048, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=29.5546558704453, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=31.1284046692607, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=30.9236947791165, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI18859837, Length=232, Percent_Identity=32.3275862068966, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=34.3195266272189, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=30.8080808080808, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24641232, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=27.8947368421053, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI116007236, Length=203, Percent_Identity=30.5418719211823, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=27.8947368421053, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24648693, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355889, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364494, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI78706930, Length=250, Percent_Identity=28.4, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706928, Length=250, Percent_Identity=28.4, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706926, Length=250, Percent_Identity=28.4, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706924, Length=250, Percent_Identity=28.4, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI78706922, Length=250, Percent_Identity=28.4, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581726, Length=145, Percent_Identity=26.8965517241379, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26209; Mature: 26078

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRIAYVTGGMGGIGTAICQRLARDGFTVVAGCGPNSPRKAKWLEQQKALGFDFVPSEG
CCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEECCCCC
NVGDWESTKAAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVT
CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMADRGWGRIINISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGEPTEIASICAWLASEESGFSTGADFSLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC
>Mature Secondary Structure 
TKRIAYVTGGMGGIGTAICQRLARDGFTVVAGCGPNSPRKAKWLEQQKALGFDFVPSEG
CCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEECCCCC
NVGDWESTKAAFDKVKAEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVT
CCCCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KQVIDGMADRGWGRIINISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNT
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEC
VSPGYIATDMVKAIRQDVLDKIIGTIPVKRLGEPTEIASICAWLASEESGFSTGADFSLN
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEC
GGLHMG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]