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The map label for this gene is potC [H]

Identifier: 187928554

GI number: 187928554

Start: 1562721

End: 1563557

Strand: Direct

Name: potC [H]

Synonym: Rpic_1470

Alternate gene names: 187928554

Gene position: 1562721-1563557 (Clockwise)

Preceding gene: 187928553

Following gene: 187928558

Centisome position: 39.64

GC content: 62.84

Gene sequence:

>837_bases
ATGAAACTCACCAAACCGATGTTCGCCCCGCACACCTCGCTCATCGAGCGCATTTGGTACTTCGCGCTGCGCGGCCTGGC
CGTGCTGACGCTGCTCTACCTTGTGCTGCCGGTGCTGGTGATCGTGCCGCTGTCGTTCTCGTCGAGCACGTTCCTCTCGT
ACCCGATTCCGAGCTATTCGCTGCGCTGGTATCAGAACCTCGTCACGTCGGACGAATGGCGCATGGCCGCCAAGAACAGC
TTCATCGTCGCGCCTGCCGCCACGATCGTGGCAACGGTACTGGGCACGCTGGCCGCCATCGGGCTGAACAAGGCCGACTT
CCGTGGCAAGGGCCTGCTGATGGCGGTGCTGGTGTCGCCGATGATCGTGCCGGTGGTGGTCGTGGGCGTTGGCATGTATC
TGTTCTTTGCCCCGCTGGGCCTGGCGAATACGTATATCGGGCTGATCCTCGCGCATGCGGCGCTGGGCGTGCCGTTTGTG
GTGACGACCGTGCTGGCGACGCTGCAGGGCTTCAATCACAACCTCGTGCGGGCAAGCCTTTCGCTGGGTGCCAACCCGGT
CGTGACGTTCTTCCGCATCACCCTGCCCGTGATCGCACCGGGCGTGATTTCCGGCGCGCTGTTTGCGTTTGCCACCTCAT
TTGATGAGGTGGTGGTGACGCTCTTCCTGGCGGGTGCCGATCAGGTGACGCTGCCACGCCAGATGTTCACAGGCATTCGC
GAGAACATTTCGCCGACGATTGCGGCGCTGGCGACGATCTTGATTGTGTTTTCGACTTGCCTGCTGCTGACGTTTGAGTG
GCTGCGGGGGCGGGCTGCGGCTAAGGCGGTGGCGTAA

Upstream 100 bases:

>100_bases
CTGGGTGCGCTGCTGTTGCTGGCGACGCTGGTGCTGTATGCCGTGTATGGACGCTTCACGCGGCCCAAGGTTCGCGTTGG
TTGAACGGAGCCCATCGAAA

Downstream 100 bases:

>100_bases
GCGGTTTGGGTTTTGGTTGTTTTCTGTGGTTCATTCCCTGTTTCAGCCCCGGCAGGGGGTGAAACAGGGAATGCGCTGCT
GTCCCAAGCATCAAGCCCCA

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKLTKPMFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLSYPIPSYSLRWYQNLVTSDEWRMAAKNS
FIVAPAATIVATVLGTLAAIGLNKADFRGKGLLMAVLVSPMIVPVVVVGVGMYLFFAPLGLANTYIGLILAHAALGVPFV
VTTVLATLQGFNHNLVRASLSLGANPVVTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIR
ENISPTIAALATILIVFSTCLLLTFEWLRGRAAAKAVA

Sequences:

>Translated_278_residues
MKLTKPMFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLSYPIPSYSLRWYQNLVTSDEWRMAAKNS
FIVAPAATIVATVLGTLAAIGLNKADFRGKGLLMAVLVSPMIVPVVVVGVGMYLFFAPLGLANTYIGLILAHAALGVPFV
VTTVLATLQGFNHNLVRASLSLGANPVVTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIR
ENISPTIAALATILIVFSTCLLLTFEWLRGRAAAKAVA
>Mature_278_residues
MKLTKPMFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLSYPIPSYSLRWYQNLVTSDEWRMAAKNS
FIVAPAATIVATVLGTLAAIGLNKADFRGKGLLMAVLVSPMIVPVVVVGVGMYLFFAPLGLANTYIGLILAHAALGVPFV
VTTVLATLQGFNHNLVRASLSLGANPVVTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIR
ENISPTIAALATILIVFSTCLLLTFEWLRGRAAAKAVA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=219, Percent_Identity=32.4200913242009, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787081, Length=239, Percent_Identity=32.2175732217573, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787714, Length=240, Percent_Identity=32.0833333333333, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788764, Length=207, Percent_Identity=27.0531400966184, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787080, Length=132, Percent_Identity=28.030303030303, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786980, Length=145, Percent_Identity=33.7931034482759, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29831; Mature: 29831

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTKPMFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLSYPIPSYS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHH
LRWYQNLVTSDEWRMAAKNSFIVAPAATIVATVLGTLAAIGLNKADFRGKGLLMAVLVSP
HHHHHHHHCCCHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
MIVPVVVVGVGMYLFFAPLGLANTYIGLILAHAALGVPFVVTTVLATLQGFNHNLVRASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHH
SLGANPVVTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ENISPTIAALATILIVFSTCLLLTFEWLRGRAAAKAVA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLTKPMFAPHTSLIERIWYFALRGLAVLTLLYLVLPVLVIVPLSFSSSTFLSYPIPSYS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHH
LRWYQNLVTSDEWRMAAKNSFIVAPAATIVATVLGTLAAIGLNKADFRGKGLLMAVLVSP
HHHHHHHHCCCHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
MIVPVVVVGVGMYLFFAPLGLANTYIGLILAHAALGVPFVVTTVLATLQGFNHNLVRASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHH
SLGANPVVTFFRITLPVIAPGVISGALFAFATSFDEVVVTLFLAGADQVTLPRQMFTGIR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ENISPTIAALATILIVFSTCLLLTFEWLRGRAAAKAVA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]