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The map label for this gene is ccpA [H]

Identifier: 187928505

GI number: 187928505

Start: 1508584

End: 1509654

Strand: Reverse

Name: ccpA [H]

Synonym: Rpic_1419

Alternate gene names: 187928505

Gene position: 1509654-1508584 (Counterclockwise)

Preceding gene: 187928507

Following gene: 187928504

Centisome position: 38.29

GC content: 69.37

Gene sequence:

>1071_bases
GTGGGCAGCAGCATCAAGGACGTGGCGACGCACGCCGGCATTTCGATTGCCACCGTGTCGCGGGCGGTCAATACGCCGGA
GCGGGTGAGTGCCTCGACGCTGGCCCGAGTGCAGGCGGCCATGGATGCGCTGCACTATCGCCCGAACGCGCTGGGCCGCC
AGTTGCGCGCCGAGCGCACGGGCTTGCTTGGCGTGGTGCTGCCGTCGCTCGCCAACCCCGTGTTTGCCGAGTGCATGCAG
GGCATCGAGGAAGCCGCATCCATCACCGGCCAGCGTGTGATGCTCATGACGACCGCCTACGACCGCGAGCGCGAGGCCCG
CGCCATCGAGACCATGCTCGAGCAACGTGTCGACGGTCTGATCCTGACCGTGGCCGATGCAGCCGCCAATCCGCATCTCG
ATCGACTGGACGCCGAGCACGTGCCTTATGTGCTGGTCTACAACGACACGGTCGGCCAGGCACGCATTCCGGCGCGCTGC
TGCGTGACGGTCGACAACCGGGCCGCTGCGCGCGACGCCATCCGCGCGTTGCTGGCGCAAGGGCACCGACAGATCCGTAT
GCTCACCGGCACGCTGGCGGCCTCGGACCGTGCGGCCCTGCGCCACGACGGCTACCGCGAAGCGCTGGAGGCGGCCGGCA
TTGCGCCGCAGCCGCCCGTCGAAATTGACTTCAATGCCGATGCCATGCTGCCCGCCGAGTTGGCCCGGCTGCTCGCACCG
CCGCGCCCGACCGCCATTTTCTGCAGCAACGACCGCCTCGCGCTGCTCACCATCCGCTCGCTGCGCGAGATGGGCCTGCG
CGTGCCCGAAGACGTGAGCGTGGTCGGCTTTGATGGCCTGGCGATAGGGCAGTGGCTCTCGCCCACGCTGGCCACCGTGG
CGCAGCCGCACCGCCGGATCGGCACCGATGCGGCCACGGCGCTGGCTCGCCGCATCGCCGGCGAGGTGGTCCCCTCGATT
ACCTTGCCGCACCGCCTGCTGGCGGGCGGCACGCTGGCCCGAGCGCCGGCTGAAACGTCTCTCTCCGTTGTTTCTTCCCT
CACGTCTGATACGCAAGGAGCGTCTCGATGA

Upstream 100 bases:

>100_bases
GCTGCGTTGCGGTAATGGCTGCATCGCAGCATCGATTGTCATGAAACAGTCACTGCGCGCACCTAGCATGTAAACGTTTA
CACCTTCCCGGGGGCGCGTA

Downstream 100 bases:

>100_bases
AACGTCTCGTTCAATGGCTGCGCGCGTGCGGCCTCGTGGCTGCCGGCGCCATCGCCCTGGCTACGCCGGTGCAGGCACAG
CCCGCGGGCCAGCAGGTCGC

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MGSSIKDVATHAGISIATVSRAVNTPERVSASTLARVQAAMDALHYRPNALGRQLRAERTGLLGVVLPSLANPVFAECMQ
GIEEAASITGQRVMLMTTAYDREREARAIETMLEQRVDGLILTVADAAANPHLDRLDAEHVPYVLVYNDTVGQARIPARC
CVTVDNRAAARDAIRALLAQGHRQIRMLTGTLAASDRAALRHDGYREALEAAGIAPQPPVEIDFNADAMLPAELARLLAP
PRPTAIFCSNDRLALLTIRSLREMGLRVPEDVSVVGFDGLAIGQWLSPTLATVAQPHRRIGTDAATALARRIAGEVVPSI
TLPHRLLAGGTLARAPAETSLSVVSSLTSDTQGASR

Sequences:

>Translated_356_residues
MGSSIKDVATHAGISIATVSRAVNTPERVSASTLARVQAAMDALHYRPNALGRQLRAERTGLLGVVLPSLANPVFAECMQ
GIEEAASITGQRVMLMTTAYDREREARAIETMLEQRVDGLILTVADAAANPHLDRLDAEHVPYVLVYNDTVGQARIPARC
CVTVDNRAAARDAIRALLAQGHRQIRMLTGTLAASDRAALRHDGYREALEAAGIAPQPPVEIDFNADAMLPAELARLLAP
PRPTAIFCSNDRLALLTIRSLREMGLRVPEDVSVVGFDGLAIGQWLSPTLATVAQPHRRIGTDAATALARRIAGEVVPSI
TLPHRLLAGGTLARAPAETSLSVVSSLTSDTQGASR
>Mature_355_residues
GSSIKDVATHAGISIATVSRAVNTPERVSASTLARVQAAMDALHYRPNALGRQLRAERTGLLGVVLPSLANPVFAECMQG
IEEAASITGQRVMLMTTAYDREREARAIETMLEQRVDGLILTVADAAANPHLDRLDAEHVPYVLVYNDTVGQARIPARCC
VTVDNRAAARDAIRALLAQGHRQIRMLTGTLAASDRAALRHDGYREALEAAGIAPQPPVEIDFNADAMLPAELARLLAPP
RPTAIFCSNDRLALLTIRSLREMGLRVPEDVSVVGFDGLAIGQWLSPTLATVAQPHRRIGTDAATALARRIAGEVVPSIT
LPHRLLAGGTLARAPAETSLSVVSSLTSDTQGASR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=322, Percent_Identity=32.6086956521739, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI48994940, Length=333, Percent_Identity=34.8348348348348, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1790194, Length=313, Percent_Identity=31.9488817891374, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787948, Length=339, Percent_Identity=31.858407079646, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790715, Length=335, Percent_Identity=30.4477611940298, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788474, Length=296, Percent_Identity=31.7567567567568, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789202, Length=324, Percent_Identity=30.5555555555556, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786540, Length=322, Percent_Identity=32.9192546583851, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=31, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=26.5861027190332, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787906, Length=343, Percent_Identity=28.2798833819242, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786268, Length=310, Percent_Identity=24.5161290322581, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790689, Length=329, Percent_Identity=23.7082066869301, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37912; Mature: 37781

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSIKDVATHAGISIATVSRAVNTPERVSASTLARVQAAMDALHYRPNALGRQLRAERT
CCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GLLGVVLPSLANPVFAECMQGIEEAASITGQRVMLMTTAYDREREARAIETMLEQRVDGL
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCE
ILTVADAAANPHLDRLDAEHVPYVLVYNDTVGQARIPARCCVTVDNRAAARDAIRALLAQ
EEEEECCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHC
GHRQIRMLTGTLAASDRAALRHDGYREALEAAGIAPQPPVEIDFNADAMLPAELARLLAP
CCHHEEHHHHHHHCCCHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCC
PRPTAIFCSNDRLALLTIRSLREMGLRVPEDVSVVGFDGLAIGQWLSPTLATVAQPHRRI
CCCCEEEECCCCEEEHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
GTDAATALARRIAGEVVPSITLPHRLLAGGTLARAPAETSLSVVSSLTSDTQGASR
CCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GSSIKDVATHAGISIATVSRAVNTPERVSASTLARVQAAMDALHYRPNALGRQLRAERT
CCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
GLLGVVLPSLANPVFAECMQGIEEAASITGQRVMLMTTAYDREREARAIETMLEQRVDGL
CHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCE
ILTVADAAANPHLDRLDAEHVPYVLVYNDTVGQARIPARCCVTVDNRAAARDAIRALLAQ
EEEEECCCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHC
GHRQIRMLTGTLAASDRAALRHDGYREALEAAGIAPQPPVEIDFNADAMLPAELARLLAP
CCHHEEHHHHHHHCCCHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHCC
PRPTAIFCSNDRLALLTIRSLREMGLRVPEDVSVVGFDGLAIGQWLSPTLATVAQPHRRI
CCCCEEEECCCCEEEHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
GTDAATALARRIAGEVVPSITLPHRLLAGGTLARAPAETSLSVVSSLTSDTQGASR
CCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]