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The map label for this gene is cutS [H]

Identifier: 187928441

GI number: 187928441

Start: 1451064

End: 1451591

Strand: Reverse

Name: cutS [H]

Synonym: Rpic_1354

Alternate gene names: 187928441

Gene position: 1451591-1451064 (Counterclockwise)

Preceding gene: 187928442

Following gene: 187928440

Centisome position: 36.82

GC content: 65.72

Gene sequence:

>528_bases
ATGGCGATCAGCCTCAAGCTGTCGGTCAACGGTGCGCCTGTCACCGTCAGTGTCGAACCCCATACCCTGCTAGTTCAATT
GTTGCGCGAGCACCTTCGCCTGACCGGCACGCACGTCGGCTGCGATACGGCGCAATGCGGTGCCTGCACCGTGCATATGA
ACGGGCGGGCGGTGAAGTCCTGCAACATCCTGGCCGTGCAGGCCGACGGCGCCGAGGTGACAACCATTGAAGGCCTGTCG
AAAGATGGTGCGCTGCACCCGATGCAGGAAGCCTTTCGCCAATGCCATGGCCTGCAATGCGGCTTCTGTACCCCGGGCAT
GGTGATGGCGGCCACGGCGCTGGTTGCGCAACACCCGCATCCCGACGAGCACACGGTGCGCGAGCAGCTCGACGGCAACC
TGTGCCGCTGCACGGGTTATCACAACATCGTGCGCGCCGTCATGCACGGAGCCGAAGCCATGGCCGAAGCCCAGGGCGAC
GATGCCTCGCTGCAAAGCCTGGCCGCGGCGCGGGCCCACGCCGCCTGA

Upstream 100 bases:

>100_bases
AGTAGAGCCGCGACCACCCATATCGAGACCACGCGTGCATCTTCCCAGCCAGGAAGACGCACAGCATGGCACCCGGCGCC
CATCCCCCAAGGAGACTCCC

Downstream 100 bases:

>100_bases
CCCCAGCGAGGAGACCACCATGAACGCTCCCGCAGAACCCAACAACCACCTGATTGGCGCGTCCGTCAAGCGCAAGGAAG
ACTTCCGCTTCCTGACGGGC

Product: (2Fe-2S)-binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MAISLKLSVNGAPVTVSVEPHTLLVQLLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKSCNILAVQADGAEVTTIEGLS
KDGALHPMQEAFRQCHGLQCGFCTPGMVMAATALVAQHPHPDEHTVREQLDGNLCRCTGYHNIVRAVMHGAEAMAEAQGD
DASLQSLAAARAHAA

Sequences:

>Translated_175_residues
MAISLKLSVNGAPVTVSVEPHTLLVQLLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKSCNILAVQADGAEVTTIEGLS
KDGALHPMQEAFRQCHGLQCGFCTPGMVMAATALVAQHPHPDEHTVREQLDGNLCRCTGYHNIVRAVMHGAEAMAEAQGD
DASLQSLAAARAHAA
>Mature_174_residues
AISLKLSVNGAPVTVSVEPHTLLVQLLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKSCNILAVQADGAEVTTIEGLSK
DGALHPMQEAFRQCHGLQCGFCTPGMVMAATALVAQHPHPDEHTVREQLDGNLCRCTGYHNIVRAVMHGAEAMAEAQGDD
ASLQSLAAARAHAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=157, Percent_Identity=41.4012738853503, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=38.8535031847134, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=42.0731707317073, Blast_Score=129, Evalue=9e-32,
Organism=Escherichia coli, GI1789232, Length=149, Percent_Identity=44.2953020134228, Blast_Score=124, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=42.9487179487179, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=37.5, Blast_Score=112, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=36.1842105263158, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17737937, Length=168, Percent_Identity=41.0714285714286, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=39.375, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=39.375, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24647201, Length=154, Percent_Identity=35.7142857142857, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24647199, Length=154, Percent_Identity=36.3636363636364, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647193, Length=157, Percent_Identity=34.3949044585987, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 18394; Mature: 18263

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISLKLSVNGAPVTVSVEPHTLLVQLLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKS
CEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECC
CNILAVQADGAEVTTIEGLSKDGALHPMQEAFRQCHGLQCGFCTPGMVMAATALVAQHPH
CEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
PDEHTVREQLDGNLCRCTGYHNIVRAVMHGAEAMAEAQGDDASLQSLAAARAHAA
CCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AISLKLSVNGAPVTVSVEPHTLLVQLLREHLRLTGTHVGCDTAQCGACTVHMNGRAVKS
EEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECC
CNILAVQADGAEVTTIEGLSKDGALHPMQEAFRQCHGLQCGFCTPGMVMAATALVAQHPH
CEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
PDEHTVREQLDGNLCRCTGYHNIVRAVMHGAEAMAEAQGDDASLQSLAAARAHAA
CCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]