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The map label for this gene is ydfG [C]

Identifier: 187928239

GI number: 187928239

Start: 1229700

End: 1230485

Strand: Reverse

Name: ydfG [C]

Synonym: Rpic_1148

Alternate gene names: 187928239

Gene position: 1230485-1229700 (Counterclockwise)

Preceding gene: 187928240

Following gene: 187928238

Centisome position: 31.21

GC content: 65.01

Gene sequence:

>786_bases
ATGACTGACCGCCGCGCCCATTGCATTGTCATCACCGGCGCCAGCGCAGGCATTGGCCAGGCACTAGCTCGCGCATACGC
GGCACCCGGCGTCACGCTCGGACTGGTTGCGCGCGATGCAGTGCGGTTGGAAGCCTGCGCCGATCAGTGCCGGCAGGCCG
GCGCCACCGTAATCACTGCGCAATTGGACGTCCGTGACGCTGGGGCCGTCGCCGCATGGCTGACGGCATTCGACGATGCG
CACCCGATCGACCTGCTGATCGCAAACGCTGGCGTGGCAAATACATTGTCTTCGGCCAGCGACTGGGAAGACCTTGCGCG
CACACGCGAGGTCTTCGACACCAACTTCTATGGGGCGTTTCATACGCTGTTGCCTGTGCTGGCACGCCTGCGTGCACGCA
AGCGTGGCCATGTGGCGGTGATCAGCTCGCTGGCGGCCATTCGCGGCATGGCCATCTCGCCGGCTTATTGCGCGAGCAAG
TCGGCAATCAAGGCTTATGGAGAATCGGTGCGACCGTTGCTGGCGGCGGACGGGGTGCTCCTGTCATTGGTCTTTCCCGG
CTTCGTCAAGACGGCGATGAGCGACGTCTTCCCCGGCGATAAGCCTTTCCTGTGGTCAGCTGACAAGGCGGCTCGCCACA
TCCGCGCCAAGCTGGATGCGGGGCGAGCGGAGATTGCATTTCCGGCGCTGCTGGCGCTGGGTATGCGCCTGCTGCCACTG
CTGCCTCCACGGCTGGGGGACCGCATCCTGGACCGGCTGTCCTACCTGCCCCGGGCAGAGCGTTAA

Upstream 100 bases:

>100_bases
TACCTAGTGCACCACACGCAAATCAACGGCGACTTTTACACACGCACCGGCATCGCCATGGCCACGGCCGGCGCGGTGAA
GCGGCTGGAGGCTGCGGCCC

Downstream 100 bases:

>100_bases
CGCAGCATGCCAGGCGCAGCCATTTTCCTGCTTGCCCTGGCGATGTCGTTCCTGCCGGACGCCATCGCCTTGCCGCGTTC
CGCGCCGCCGTGGCGGCGCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTDRRAHCIVITGASAGIGQALARAYAAPGVTLGLVARDAVRLEACADQCRQAGATVITAQLDVRDAGAVAAWLTAFDDA
HPIDLLIANAGVANTLSSASDWEDLARTREVFDTNFYGAFHTLLPVLARLRARKRGHVAVISSLAAIRGMAISPAYCASK
SAIKAYGESVRPLLAADGVLLSLVFPGFVKTAMSDVFPGDKPFLWSADKAARHIRAKLDAGRAEIAFPALLALGMRLLPL
LPPRLGDRILDRLSYLPRAER

Sequences:

>Translated_261_residues
MTDRRAHCIVITGASAGIGQALARAYAAPGVTLGLVARDAVRLEACADQCRQAGATVITAQLDVRDAGAVAAWLTAFDDA
HPIDLLIANAGVANTLSSASDWEDLARTREVFDTNFYGAFHTLLPVLARLRARKRGHVAVISSLAAIRGMAISPAYCASK
SAIKAYGESVRPLLAADGVLLSLVFPGFVKTAMSDVFPGDKPFLWSADKAARHIRAKLDAGRAEIAFPALLALGMRLLPL
LPPRLGDRILDRLSYLPRAER
>Mature_260_residues
TDRRAHCIVITGASAGIGQALARAYAAPGVTLGLVARDAVRLEACADQCRQAGATVITAQLDVRDAGAVAAWLTAFDDAH
PIDLLIANAGVANTLSSASDWEDLARTREVFDTNFYGAFHTLLPVLARLRARKRGHVAVISSLAAIRGMAISPAYCASKS
AIKAYGESVRPLLAADGVLLSLVFPGFVKTAMSDVFPGDKPFLWSADKAARHIRAKLDAGRAEIAFPALLALGMRLLPLL
PPRLGDRILDRLSYLPRAER

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=210, Percent_Identity=35.2380952380952, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=30.0518134715026, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=27.4111675126904, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223718074, Length=193, Percent_Identity=32.6424870466321, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI40807363, Length=257, Percent_Identity=29.5719844357977, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19743808, Length=211, Percent_Identity=27.4881516587678, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI150247226, Length=224, Percent_Identity=29.0178571428571, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=29.2307692307692, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=29.4736842105263, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787820, Length=231, Percent_Identity=27.7056277056277, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=33.1578947368421, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787335, Length=197, Percent_Identity=25.8883248730964, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=192, Percent_Identity=29.1666666666667, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790717, Length=200, Percent_Identity=27.5, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=245, Percent_Identity=26.1224489795918, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=232, Percent_Identity=29.3103448275862, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=33.1658291457286, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24580925, Length=218, Percent_Identity=32.1100917431193, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=188, Percent_Identity=34.0425531914894, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=262, Percent_Identity=27.4809160305344, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644339, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364892, Length=257, Percent_Identity=26.8482490272374, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648944, Length=205, Percent_Identity=31.7073170731707, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27752; Mature: 27621

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRRAHCIVITGASAGIGQALARAYAAPGVTLGLVARDAVRLEACADQCRQAGATVITA
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEE
QLDVRDAGAVAAWLTAFDDAHPIDLLIANAGVANTLSSASDWEDLARTREVFDTNFYGAF
EECCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHH
HTLLPVLARLRARKRGHVAVISSLAAIRGMAISPAYCASKSAIKAYGESVRPLLAADGVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
LSLVFPGFVKTAMSDVFPGDKPFLWSADKAARHIRAKLDAGRAEIAFPALLALGMRLLPL
HHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
LPPRLGDRILDRLSYLPRAER
CCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TDRRAHCIVITGASAGIGQALARAYAAPGVTLGLVARDAVRLEACADQCRQAGATVITA
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEEE
QLDVRDAGAVAAWLTAFDDAHPIDLLIANAGVANTLSSASDWEDLARTREVFDTNFYGAF
EECCCHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHHCCCHHHH
HTLLPVLARLRARKRGHVAVISSLAAIRGMAISPAYCASKSAIKAYGESVRPLLAADGVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHH
LSLVFPGFVKTAMSDVFPGDKPFLWSADKAARHIRAKLDAGRAEIAFPALLALGMRLLPL
HHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
LPPRLGDRILDRLSYLPRAER
CCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]