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The map label for this gene is insF1 [C]

Identifier: 187928232

GI number: 187928232

Start: 1216251

End: 1216802

Strand: Direct

Name: insF1 [C]

Synonym: Rpic_1141

Alternate gene names: 187928232

Gene position: 1216251-1216802 (Clockwise)

Preceding gene: 187928231

Following gene: 187928233

Centisome position: 30.85

GC content: 63.04

Gene sequence:

>552_bases
GTGAAGGCGTACATCGACCGCTACCGCGATGCGTACGGGGTCGAGCCCATCTGCAAGGTCTTGCAGATTGCCCCGTCTTG
CTACCGGCGCCACGCGGCCCAGCAACGCAAACCGGCGCTGCGCTGCAAACGTGCCCAACGCGACGACGCGCTTATCCCCG
ACATCGAGCGCGTCTGGCATGCCAACTGGCAGGTGTATGGCGCCGACAAGGTCTGGAAGCCGATGAATCGCGAGGGCATC
CGTGTCGCGCGTTGCACAGTCGAACGCTTGACGAAGCGTCAGGGGTTGCGGGGCGTGCGTCGTGGCAAGGTGGTGCGGAC
CACGACGCCGGATGCTTCGGCGCCATGCCCATTGGACCGGGTCCAGCGAGTGTTCAAAGCCGAGCGGCCCAATCAACTGT
GGGTGTCCGACTTCACTTATGTCAGCACTTGGCAGGGCTGGCTGTACGTGGCGTTCGTCATCGACGTGTTCGCGCGGCGC
ATTGTGGGCTGGCGGGTGAGCAGCACCATGCGTACCTTTCGCCAACGGAACCTTTTCTGTCATTCAATCTAG

Upstream 100 bases:

>100_bases
GGTTGCAGCGCGAGGTCAAGGAACTGAGCCGCGCCAACGAGATTCTCAAGACGGCCAGCGCGTTTTTTGCGCAGGCGGAG
CTCGACCGCCGACTCAAGTC

Downstream 100 bases:

>100_bases
ATACATTGCCGGTTGGTGAGTTGGTCAAGCTGGAAGCCATAGCCGCAGCATCCGATGACTACATTCTCAGCGGCCATCTG
CTTCGCGATGTGGATGTCCA

Product: Integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKAYIDRYRDAYGVEPICKVLQIAPSCYRRHAAQQRKPALRCKRAQRDDALIPDIERVWHANWQVYGADKVWKPMNREGI
RVARCTVERLTKRQGLRGVRRGKVVRTTTPDASAPCPLDRVQRVFKAERPNQLWVSDFTYVSTWQGWLYVAFVIDVFARR
IVGWRVSSTMRTFRQRNLFCHSI

Sequences:

>Translated_183_residues
MKAYIDRYRDAYGVEPICKVLQIAPSCYRRHAAQQRKPALRCKRAQRDDALIPDIERVWHANWQVYGADKVWKPMNREGI
RVARCTVERLTKRQGLRGVRRGKVVRTTTPDASAPCPLDRVQRVFKAERPNQLWVSDFTYVSTWQGWLYVAFVIDVFARR
IVGWRVSSTMRTFRQRNLFCHSI
>Mature_183_residues
MKAYIDRYRDAYGVEPICKVLQIAPSCYRRHAAQQRKPALRCKRAQRDDALIPDIERVWHANWQVYGADKVWKPMNREGI
RVARCTVERLTKRQGLRGVRRGKVVRTTTPDASAPCPLDRVQRVFKAERPNQLWVSDFTYVSTWQGWLYVAFVIDVFARR
IVGWRVSSTMRTFRQRNLFCHSI

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=172, Percent_Identity=47.6744186046512, Blast_Score=159, Evalue=1e-39,
Organism=Escherichia coli, GI1788405, Length=172, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1787263, Length=172, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786753, Length=172, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786570, Length=172, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786490, Length=172, Percent_Identity=29.0697674418605, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1789981, Length=164, Percent_Identity=26.219512195122, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 21583; Mature: 21583

Theoretical pI: Translated: 11.18; Mature: 11.18

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYIDRYRDAYGVEPICKVLQIAPSCYRRHAAQQRKPALRCKRAQRDDALIPDIERVWH
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHH
ANWQVYGADKVWKPMNREGIRVARCTVERLTKRQGLRGVRRGKVVRTTTPDASAPCPLDR
CCCEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHH
VQRVFKAERPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWRVSSTMRTFRQRNLFC
HHHHHHHCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HSI
CCC
>Mature Secondary Structure
MKAYIDRYRDAYGVEPICKVLQIAPSCYRRHAAQQRKPALRCKRAQRDDALIPDIERVWH
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHH
ANWQVYGADKVWKPMNREGIRVARCTVERLTKRQGLRGVRRGKVVRTTTPDASAPCPLDR
CCCEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHH
VQRVFKAERPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWRVSSTMRTFRQRNLFC
HHHHHHHCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HSI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]