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The map label for this gene is glnL [H]

Identifier: 187928181

GI number: 187928181

Start: 1159318

End: 1160520

Strand: Direct

Name: glnL [H]

Synonym: Rpic_1088

Alternate gene names: 187928181

Gene position: 1159318-1160520 (Clockwise)

Preceding gene: 187928180

Following gene: 187928182

Centisome position: 29.41

GC content: 64.34

Gene sequence:

>1203_bases
ATGCGTCGACTGATCCGCAAAGCGGCACGCCGCGATGAACAGGAACAGACGACGCCATCCGCGCCGTCACCCTCCGCCGC
CGGTGTGGAGGTCTCCGTAGGCGAGCCCATCGACGGGCCGCCGCCGATTCCGTTTTCACATGGTGCACCGCCATCATTCC
CTGGGCTCGACGCGGTGCCCAATCCCATCCTCTTCGTCCGCCATCCAGCGCTGACGGTCTTCTACGCCAACCCCGCCGCG
GAAGCCGCGTTGGCCGTGTCTCGCCGCCAACTGGTGGAGATGTCGCTGTACGAGCTGTTTGCCGACCCGTCGGAGCTGGG
CGAGATGATCGCCACCGTGGCGGCTCGCCAGTTCGATGCCAAGCGGCGCGACGTGTCACTTGAGCGCGTCGGCCATGAGC
CGCTGCACGCGCACGCCGTCGTGGGCGCGCTCGACTTTGTGCCCGGATCGGTGCTGCTTGAGCTGCTGCCCAACGAGCAG
AAGATCCGTAGCGAGCGCGAGGAGCGTCTGCTCGACCTGACTTCCGCCAACAAAGAGCTGATCCGCAACCTTGCGCACGA
GATCAAGAATCCGTTGGGCGGTATTCGCGGCGCGGCGCAGTTGCTGGAGTTCGAACTGCCGGAGCGCTCGCTGCGCGAGT
ACACGCAGGTCATCATCAAGGAATCCGACCGGCTGCAGACCCTGGTCGACCGCCTGCTGGAACCGCACCGGCATCCGCAT
ATCGTTGGCGATGTGAACATCCACGAGGTACTGGAGCGGGTGCGCTCGGTGGTGCTGGCGGAGTTTCCGCAGGGCCTGCG
GATCGTGCGCGACTACGACGCGAGCCTGCCGGAGTTTCGCGGCGACAAGGAGCAGCTCATCCAGGCCGTGCTCAACATCG
TTCACAACGCAGCGCATGCGCTGGGCCCTCGCATTGCGCAGGGCGATGGCGAGATCATTCTGCGCACACGCGTCGCACGC
AAAGTTACGATTGCAAAACGTCTTTACAAGCTGGCATTGGACTTGCATGTAGTGGACAACGGTCCTGGTATCCCGGACGA
CATCCGCGAGCGAATCTTCTTCCCGCTGGTGTCCGGCAGGGAGGGGGGAAGTGGGCTGGGCCTGACACTCGCGCAGACGT
TCGTGCAGCAGCACGATGGTCTGATCGAATGCGAGAGCAGGCCAGGCCAGACGGATTTCCGCATTCTCGTGCCGCTGCAC
TGA

Upstream 100 bases:

>100_bases
CTGGACCGCACCGCGCAGTTGAAGGGCGACATCGAGCGCAGCCAGGCCAATGTCGATTCCATCCGCCGGGAGCTGGGCAA
TCTCAAGGACTAGATGAACC

Downstream 100 bases:

>100_bases
AGCGCCTCAGCTTCAATAACGCAGCGCGAGGCGGCCCAGGCGAGACGAAGTCAAGCAGACGAACCAACACATGAAGCCAA
TCTGGATAGTCGACGACGAT

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRRLIRKAARRDEQEQTTPSAPSPSAAGVEVSVGEPIDGPPPIPFSHGAPPSFPGLDAVPNPILFVRHPALTVFYANPAA
EAALAVSRRQLVEMSLYELFADPSELGEMIATVAARQFDAKRRDVSLERVGHEPLHAHAVVGALDFVPGSVLLELLPNEQ
KIRSEREERLLDLTSANKELIRNLAHEIKNPLGGIRGAAQLLEFELPERSLREYTQVIIKESDRLQTLVDRLLEPHRHPH
IVGDVNIHEVLERVRSVVLAEFPQGLRIVRDYDASLPEFRGDKEQLIQAVLNIVHNAAHALGPRIAQGDGEIILRTRVAR
KVTIAKRLYKLALDLHVVDNGPGIPDDIRERIFFPLVSGREGGSGLGLTLAQTFVQQHDGLIECESRPGQTDFRILVPLH

Sequences:

>Translated_400_residues
MRRLIRKAARRDEQEQTTPSAPSPSAAGVEVSVGEPIDGPPPIPFSHGAPPSFPGLDAVPNPILFVRHPALTVFYANPAA
EAALAVSRRQLVEMSLYELFADPSELGEMIATVAARQFDAKRRDVSLERVGHEPLHAHAVVGALDFVPGSVLLELLPNEQ
KIRSEREERLLDLTSANKELIRNLAHEIKNPLGGIRGAAQLLEFELPERSLREYTQVIIKESDRLQTLVDRLLEPHRHPH
IVGDVNIHEVLERVRSVVLAEFPQGLRIVRDYDASLPEFRGDKEQLIQAVLNIVHNAAHALGPRIAQGDGEIILRTRVAR
KVTIAKRLYKLALDLHVVDNGPGIPDDIRERIFFPLVSGREGGSGLGLTLAQTFVQQHDGLIECESRPGQTDFRILVPLH
>Mature_400_residues
MRRLIRKAARRDEQEQTTPSAPSPSAAGVEVSVGEPIDGPPPIPFSHGAPPSFPGLDAVPNPILFVRHPALTVFYANPAA
EAALAVSRRQLVEMSLYELFADPSELGEMIATVAARQFDAKRRDVSLERVGHEPLHAHAVVGALDFVPGSVLLELLPNEQ
KIRSEREERLLDLTSANKELIRNLAHEIKNPLGGIRGAAQLLEFELPERSLREYTQVIIKESDRLQTLVDRLLEPHRHPH
IVGDVNIHEVLERVRSVVLAEFPQGLRIVRDYDASLPEFRGDKEQLIQAVLNIVHNAAHALGPRIAQGDGEIILRTRVAR
KVTIAKRLYKLALDLHVVDNGPGIPDDIRERIFFPLVSGREGGSGLGLTLAQTFVQQHDGLIECESRPGQTDFRILVPLH

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=344, Percent_Identity=44.1860465116279, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788549, Length=342, Percent_Identity=28.3625730994152, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=27.4900398406374, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=28.0487804878049, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44288; Mature: 44288

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLIRKAARRDEQEQTTPSAPSPSAAGVEVSVGEPIDGPPPIPFSHGAPPSFPGLDAVP
CHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
NPILFVRHPALTVFYANPAAEAALAVSRRQLVEMSLYELFADPSELGEMIATVAARQFDA
CCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KRRDVSLERVGHEPLHAHAVVGALDFVPGSVLLELLPNEQKIRSEREERLLDLTSANKEL
HHHCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHH
IRNLAHEIKNPLGGIRGAAQLLEFELPERSLREYTQVIIKESDRLQTLVDRLLEPHRHPH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
IVGDVNIHEVLERVRSVVLAEFPQGLRIVRDYDASLPEFRGDKEQLIQAVLNIVHNAAHA
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGPRIAQGDGEIILRTRVARKVTIAKRLYKLALDLHVVDNGPGIPDDIRERIFFPLVSGR
HCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCC
EGGSGLGLTLAQTFVQQHDGLIECESRPGQTDFRILVPLH
CCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECC
>Mature Secondary Structure
MRRLIRKAARRDEQEQTTPSAPSPSAAGVEVSVGEPIDGPPPIPFSHGAPPSFPGLDAVP
CHHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
NPILFVRHPALTVFYANPAAEAALAVSRRQLVEMSLYELFADPSELGEMIATVAARQFDA
CCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KRRDVSLERVGHEPLHAHAVVGALDFVPGSVLLELLPNEQKIRSEREERLLDLTSANKEL
HHHCCHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHH
IRNLAHEIKNPLGGIRGAAQLLEFELPERSLREYTQVIIKESDRLQTLVDRLLEPHRHPH
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
IVGDVNIHEVLERVRSVVLAEFPQGLRIVRDYDASLPEFRGDKEQLIQAVLNIVHNAAHA
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LGPRIAQGDGEIILRTRVARKVTIAKRLYKLALDLHVVDNGPGIPDDIRERIFFPLVSGR
HCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCC
EGGSGLGLTLAQTFVQQHDGLIECESRPGQTDFRILVPLH
CCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]