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The map label for this gene is qor [H]

Identifier: 187928140

GI number: 187928140

Start: 1113055

End: 1114029

Strand: Reverse

Name: qor [H]

Synonym: Rpic_1047

Alternate gene names: 187928140

Gene position: 1114029-1113055 (Counterclockwise)

Preceding gene: 187928145

Following gene: 187928132

Centisome position: 28.26

GC content: 63.28

Gene sequence:

>975_bases
ATGAAAGCCGTCGTCTGCAAGACCTGGGGCCCGCCCGAGTCGCTGGTGATCGAAACGCTGCCGGACCTCTCGCCGGGTGC
TGGCGAAGTCGTGATCGACGTGAAGGCTGCGGGGGTGAATTTTCCTGACGTGCTGATCATCCAGAATAAGTACCAGTTCA
AGCCGGAGCTGCCGTTTACCCCCGGCTCGGAAGTCGCGGGCGTGGTCAATGCAGTAGGCGAAGGCGTGTCGCACCTCAAG
GCCGGCGACCACGTGATCGCCTTTCTTGGCCAGGGCGCGTTTGCTTCACAGGTGAAGGCATCGGCCAAGGTGGTGATGCC
GATGCCGCCGGGCATGGCGTTCGACACCGCTGCGGCATTCACGCTCACGTATGGTACGTCGCACCACGCGGTGGTCGATC
GCGGGCAACTGAAGGCTGGTGAGACGATGCTGGTGCTGGGCGCTGCGGGCGGCGTCGGGCTGGCGGCCATCGAGATCGGC
AAGGCGATCGGCGCACGCGTGATCGCCGCAGCATCGAGCGACGAGAAGCTGGCGGTCTGCAAGGACCACGGCGCTGATGC
GCTCATCAACTATTCGACCGAAGACCTGCGCGAGTGCATCAAGGAATTGACCGACGGCAAGGGCCCGGACGTGATCTATG
ACCCGGTCGGCGGCATCTATGCGGAACCGGCGTTCCGTTCAATTGCCTGGCGTGGCCGCTACCTCGTTGTCGGATTTGCC
AATGGCGAGATCCCCAAGATGCCGCTGAACCTGGCACTGCTGAAAGGCGCATCGCTGGTTGGGGTGTTCTGGGGCGAATT
CGCTCGCCGCGAGCCGAAGGCGAATCTGGCGAACATGATGCAGATGCTCGGCTGGATGCAGGAAGGCAAGATCCGCCCGC
ATATCTCGGCGCGCTATCCGCTGGAGCAGACGACACAAGCGCTGCTGGACATGGCCGCACGCAAGGTGACGGGCAAGGTG
GTGATCCAGCCTTAA

Upstream 100 bases:

>100_bases
AACGATCGTGCTTTTATTCGGTTACACTGCCAGACGAGATCGCGTGCAATGCATGCGAGATGGCGAACAATCCAACGCAA
GACTGTTGAGGAGACACATG

Downstream 100 bases:

>100_bases
AGACTTAGGCGCCAGACAAAAAAAGCCGCGCAGGCGATCAACCTGCGCGGCTTTTTCTTTGGTGCAGCGACTTATCAGGC
CGCCTCCTCCAGCGTCGGAT

Product: alcohol dehydrogenase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKAVVCKTWGPPESLVIETLPDLSPGAGEVVIDVKAAGVNFPDVLIIQNKYQFKPELPFTPGSEVAGVVNAVGEGVSHLK
AGDHVIAFLGQGAFASQVKASAKVVMPMPPGMAFDTAAAFTLTYGTSHHAVVDRGQLKAGETMLVLGAAGGVGLAAIEIG
KAIGARVIAAASSDEKLAVCKDHGADALINYSTEDLRECIKELTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
NGEIPKMPLNLALLKGASLVGVFWGEFARREPKANLANMMQMLGWMQEGKIRPHISARYPLEQTTQALLDMAARKVTGKV
VIQP

Sequences:

>Translated_324_residues
MKAVVCKTWGPPESLVIETLPDLSPGAGEVVIDVKAAGVNFPDVLIIQNKYQFKPELPFTPGSEVAGVVNAVGEGVSHLK
AGDHVIAFLGQGAFASQVKASAKVVMPMPPGMAFDTAAAFTLTYGTSHHAVVDRGQLKAGETMLVLGAAGGVGLAAIEIG
KAIGARVIAAASSDEKLAVCKDHGADALINYSTEDLRECIKELTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
NGEIPKMPLNLALLKGASLVGVFWGEFARREPKANLANMMQMLGWMQEGKIRPHISARYPLEQTTQALLDMAARKVTGKV
VIQP
>Mature_324_residues
MKAVVCKTWGPPESLVIETLPDLSPGAGEVVIDVKAAGVNFPDVLIIQNKYQFKPELPFTPGSEVAGVVNAVGEGVSHLK
AGDHVIAFLGQGAFASQVKASAKVVMPMPPGMAFDTAAAFTLTYGTSHHAVVDRGQLKAGETMLVLGAAGGVGLAAIEIG
KAIGARVIAAASSDEKLAVCKDHGADALINYSTEDLRECIKELTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
NGEIPKMPLNLALLKGASLVGVFWGEFARREPKANLANMMQMLGWMQEGKIRPHISARYPLEQTTQALLDMAARKVTGKV
VIQP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=318, Percent_Identity=31.7610062893082, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=31.8042813455657, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=31.8042813455657, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI22538446, Length=337, Percent_Identity=31.4540059347181, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI22538444, Length=337, Percent_Identity=31.4540059347181, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=29.6636085626911, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI24308257, Length=350, Percent_Identity=26.2857142857143, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI28557745, Length=317, Percent_Identity=29.6529968454259, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI67078404, Length=288, Percent_Identity=26.0416666666667, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI41872631, Length=302, Percent_Identity=26.158940397351, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI67078406, Length=281, Percent_Identity=26.3345195729537, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI47519420, Length=333, Percent_Identity=29.4294294294294, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI197927207, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790485, Length=322, Percent_Identity=32.9192546583851, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI226510941, Length=343, Percent_Identity=24.7813411078717, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=332, Percent_Identity=28.3132530120482, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17536829, Length=318, Percent_Identity=27.3584905660377, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=327, Percent_Identity=31.1926605504587, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24581345, Length=251, Percent_Identity=25.4980079681275, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221330659, Length=250, Percent_Identity=25.6, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920632, Length=250, Percent_Identity=25.6, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550423, Length=220, Percent_Identity=26.8181818181818, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34217; Mature: 34217

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVCKTWGPPESLVIETLPDLSPGAGEVVIDVKAAGVNFPDVLIIQNKYQFKPELPFT
CCEEEECCCCCCHHHHEECCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSEVAGVVNAVGEGVSHLKAGDHVIAFLGQGAFASQVKASAKVVMPMPPGMAFDTAAAF
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCEEE
TLTYGTSHHAVVDRGQLKAGETMLVLGAAGGVGLAAIEIGKAIGARVIAAASSDEKLAVC
EEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEE
KDHGADALINYSTEDLRECIKELTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
ECCCCCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHEECCCEEEEEEC
NGEIPKMPLNLALLKGASLVGVFWGEFARREPKANLANMMQMLGWMQEGKIRPHISARYP
CCCCCCCCCEEEEECCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
LEQTTQALLDMAARKVTGKVVIQP
HHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MKAVVCKTWGPPESLVIETLPDLSPGAGEVVIDVKAAGVNFPDVLIIQNKYQFKPELPFT
CCEEEECCCCCCHHHHEECCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCC
PGSEVAGVVNAVGEGVSHLKAGDHVIAFLGQGAFASQVKASAKVVMPMPPGMAFDTAAAF
CCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCEEE
TLTYGTSHHAVVDRGQLKAGETMLVLGAAGGVGLAAIEIGKAIGARVIAAASSDEKLAVC
EEEECCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEE
KDHGADALINYSTEDLRECIKELTDGKGPDVIYDPVGGIYAEPAFRSIAWRGRYLVVGFA
ECCCCCEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHEECCCEEEEEEC
NGEIPKMPLNLALLKGASLVGVFWGEFARREPKANLANMMQMLGWMQEGKIRPHISARYP
CCCCCCCCCEEEEECCCCEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
LEQTTQALLDMAARKVTGKVVIQP
HHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]