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The map label for this gene is insF1 [C]

Identifier: 187928113

GI number: 187928113

Start: 1079448

End: 1080275

Strand: Direct

Name: insF1 [C]

Synonym: Rpic_1020

Alternate gene names: 187928113

Gene position: 1079448-1080275 (Clockwise)

Preceding gene: 187928112

Following gene: 187928115

Centisome position: 27.38

GC content: 63.53

Gene sequence:

>828_bases
GTGGGCAGGGCCTGCCGCTACATTGGCATCAGCCGCCAAGCGTACTACAAACGCCAGCAAAGCGAGACACGGCAAATCGC
GCGTGAGGCCAAGGTCTGTGCGTTGGTCAACCACTTACGGCTGCGCCAGCCGCGCTTGGGTACGCGCAAGCTCCAGCACG
TGCTGCGCACGCCGCTGGCCGAGGCAGGCATCCAGGTTGGCCGGGATCGCCTGTTCGATATCCTGCGTGCAGCCCGGCTG
CTGGTCGTGCCGCAGCGGGCGTATCACAAGACCACACACAGTCATCATCGCTTCCGGCGCCATCCCAATCTGCTCAAGGA
CGGCCCGAACCAGGTCATCCCCACCGGGCCGGAGCAGGTCTGGGTGGCCGACATTACCTATCTGCCGACCGCCCAGCGCT
GTGCGTACCTGAGTCTGGTGACTGACGCCTACTCGCGCAAGATCGTGGGCTACCGCGTGCATGACAGCCTGCATGCCGAG
TCGGTCGCCCAGGCGTTGAAGATGGCGCTGAAGACGCGCCATACGCGACAGCCTCTGGTTCATCACTCGGATCGGGGCAT
CCAATACTGTTCAGCCGAGTACCAGCGCATCCATCAGCGGCACGGCATCACGTGCTCCATGACCGATGGCTACGACTGCT
ACCAGAATGCCCTGGCCGAACGGGTCAACGGCATCCTCAAAGGGGAGTTGCTGCTCAAGCGCCCCGCCGACCTAGAGCAG
GCCGCACGCATGGTGGCGCAGGCCGTGCATATCTACAACCACGAACGGCCTCATCTGGCCTTGAAATACAAAACGCCCGA
TGCGGTGCATCGGGCGCTCGGAGACTGA

Upstream 100 bases:

>100_bases
TCGAGGCGGTGATCGACGTGATCCAGAAAGAGCATGGGGCGCGCGTCGTAAAAAAGCCTTCGGGCAGGTCCTCACGCAAA
AGCTCGTCCAAGGGCTGAGT

Downstream 100 bases:

>100_bases
GCACAGTGTCAACCTATGGCAGGACTTGACACCGCTGACAGGGGTGTCAGTGCGGCGGCAACGGGGTGCCCACGATGGTC
TGCGTCAGATGCAGCTTTTC

Product: Integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MGRACRYIGISRQAYYKRQQSETRQIAREAKVCALVNHLRLRQPRLGTRKLQHVLRTPLAEAGIQVGRDRLFDILRAARL
LVVPQRAYHKTTHSHHRFRRHPNLLKDGPNQVIPTGPEQVWVADITYLPTAQRCAYLSLVTDAYSRKIVGYRVHDSLHAE
SVAQALKMALKTRHTRQPLVHHSDRGIQYCSAEYQRIHQRHGITCSMTDGYDCYQNALAERVNGILKGELLLKRPADLEQ
AARMVAQAVHIYNHERPHLALKYKTPDAVHRALGD

Sequences:

>Translated_275_residues
MGRACRYIGISRQAYYKRQQSETRQIAREAKVCALVNHLRLRQPRLGTRKLQHVLRTPLAEAGIQVGRDRLFDILRAARL
LVVPQRAYHKTTHSHHRFRRHPNLLKDGPNQVIPTGPEQVWVADITYLPTAQRCAYLSLVTDAYSRKIVGYRVHDSLHAE
SVAQALKMALKTRHTRQPLVHHSDRGIQYCSAEYQRIHQRHGITCSMTDGYDCYQNALAERVNGILKGELLLKRPADLEQ
AARMVAQAVHIYNHERPHLALKYKTPDAVHRALGD
>Mature_274_residues
GRACRYIGISRQAYYKRQQSETRQIAREAKVCALVNHLRLRQPRLGTRKLQHVLRTPLAEAGIQVGRDRLFDILRAARLL
VVPQRAYHKTTHSHHRFRRHPNLLKDGPNQVIPTGPEQVWVADITYLPTAQRCAYLSLVTDAYSRKIVGYRVHDSLHAES
VAQALKMALKTRHTRQPLVHHSDRGIQYCSAEYQRIHQRHGITCSMTDGYDCYQNALAERVNGILKGELLLKRPADLEQA
ARMVAQAVHIYNHERPHLALKYKTPDAVHRALGD

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=206, Percent_Identity=31.5533980582524, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1788405, Length=232, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787263, Length=232, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786753, Length=232, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786570, Length=232, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786490, Length=232, Percent_Identity=31.0344827586207, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789981, Length=166, Percent_Identity=31.9277108433735, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31572; Mature: 31441

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRACRYIGISRQAYYKRQQSETRQIAREAKVCALVNHLRLRQPRLGTRKLQHVLRTPLA
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHH
EAGIQVGRDRLFDILRAARLLVVPQRAYHKTTHSHHRFRRHPNLLKDGPNQVIPTGPEQV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCE
WVADITYLPTAQRCAYLSLVTDAYSRKIVGYRVHDSLHAESVAQALKMALKTRHTRQPLV
EEEEEEECCCHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HHSDRGIQYCSAEYQRIHQRHGITCSMTDGYDCYQNALAERVNGILKGELLLKRPADLEQ
HCCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AARMVAQAVHIYNHERPHLALKYKTPDAVHRALGD
HHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCC
>Mature Secondary Structure 
GRACRYIGISRQAYYKRQQSETRQIAREAKVCALVNHLRLRQPRLGTRKLQHVLRTPLA
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHH
EAGIQVGRDRLFDILRAARLLVVPQRAYHKTTHSHHRFRRHPNLLKDGPNQVIPTGPEQV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCE
WVADITYLPTAQRCAYLSLVTDAYSRKIVGYRVHDSLHAESVAQALKMALKTRHTRQPLV
EEEEEEECCCHHHHHHHHHHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHH
HHSDRGIQYCSAEYQRIHQRHGITCSMTDGYDCYQNALAERVNGILKGELLLKRPADLEQ
HCCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AARMVAQAVHIYNHERPHLALKYKTPDAVHRALGD
HHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]