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The map label for this gene is uxuR [H]

Identifier: 187928040

GI number: 187928040

Start: 1000337

End: 1001092

Strand: Reverse

Name: uxuR [H]

Synonym: Rpic_0945

Alternate gene names: 187928040

Gene position: 1001092-1000337 (Counterclockwise)

Preceding gene: 187928046

Following gene: 187928030

Centisome position: 25.39

GC content: 64.68

Gene sequence:

>756_bases
ATGCCCACCGCCAGTTCGCCCGCAACGCACGTGCGCCGCACCCAAAGCCTGGCGGACGTAGTGGTGGACCACATCAAAGG
GCGCATCGCCAACGAATCGCTGCGCATTGGCGACAAGCTGCCGACGGAATCCGCATTGATGGAAGCGCTGGGCGTGAGCC
GCACGGTGATACGCGAAGCCATTTCGCGCCTGCAAGCCAAGGGGATGATCGAAACGCGGCACGGCATCGGCAGCTTTGTC
CTGCCGCCGCGCGCAGACAACAGCATCCCGCTGGGCGATGCCTCCACGATGCACGACATTCTGAGCATGCTGGAATTGCG
CGTCGCCATTGAGACGGAGTGCGCTGGCCTGGCCGCACAGCGCATTTCTCCCACCGAGATCGATGCCCTGCGTTTGGCAC
TCGAAGCCATTGAGCAGGACCAGGCGGACGGCAACGACAGCGCCACCTCCGACCTGCAGTTTCACCTCAGCATCGCGCGC
GCCACCGGCAATGAACATTTTGTCGGCGCCCTCGCCCAACTCGGCAAGACGCTCATCCCTCGCACGCGGATCGGGCTGGC
ACAGGTCGGATACCTGAACGCTCCGGAACTGCGCGCCACGGTCAACCGCGAGCACCACAGCGTCTTTGAAGCCATCGCCC
GCAAAGACCCTGAAGCCGCCCGCGCTGCCATGCGCATGCATCTGTCAAACAGCCGGGAACGCCTGCGTCGTGCGCACGAA
GCGGCTGGCACTCAATCGGCCGCGACAGGCAGCTGA

Upstream 100 bases:

>100_bases
CATCACGTATGTCATCAGTCGTCGTACAACACGGATGCGACTATAATTGACACATTCCGACCGAACCACCCCTGGTAAAC
CCGCCCCTCCCGGAGACCGC

Downstream 100 bases:

>100_bases
GCCGGCCAATACGGCCCCATGTTGTACGACGTCTTACTAGTTGCGCAGCGCCTCGCCCATTCGCCGACCCTCAGCGCTGT
TGATAAAGATTTGCATTCGC

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MPTASSPATHVRRTQSLADVVVDHIKGRIANESLRIGDKLPTESALMEALGVSRTVIREAISRLQAKGMIETRHGIGSFV
LPPRADNSIPLGDASTMHDILSMLELRVAIETECAGLAAQRISPTEIDALRLALEAIEQDQADGNDSATSDLQFHLSIAR
ATGNEHFVGALAQLGKTLIPRTRIGLAQVGYLNAPELRATVNREHHSVFEAIARKDPEAARAAMRMHLSNSRERLRRAHE
AAGTQSAATGS

Sequences:

>Translated_251_residues
MPTASSPATHVRRTQSLADVVVDHIKGRIANESLRIGDKLPTESALMEALGVSRTVIREAISRLQAKGMIETRHGIGSFV
LPPRADNSIPLGDASTMHDILSMLELRVAIETECAGLAAQRISPTEIDALRLALEAIEQDQADGNDSATSDLQFHLSIAR
ATGNEHFVGALAQLGKTLIPRTRIGLAQVGYLNAPELRATVNREHHSVFEAIARKDPEAARAAMRMHLSNSRERLRRAHE
AAGTQSAATGS
>Mature_250_residues
PTASSPATHVRRTQSLADVVVDHIKGRIANESLRIGDKLPTESALMEALGVSRTVIREAISRLQAKGMIETRHGIGSFVL
PPRADNSIPLGDASTMHDILSMLELRVAIETECAGLAAQRISPTEIDALRLALEAIEQDQADGNDSATSDLQFHLSIARA
TGNEHFVGALAQLGKTLIPRTRIGLAQVGYLNAPELRATVNREHHSVFEAIARKDPEAARAAMRMHLSNSRERLRRAHEA
AGTQSAATGS

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=203, Percent_Identity=32.0197044334975, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI87082208, Length=219, Percent_Identity=32.8767123287671, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790032, Length=234, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786303, Length=228, Percent_Identity=32.4561403508772, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789353, Length=231, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1789621, Length=224, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI48994955, Length=213, Percent_Identity=26.2910798122066, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27025; Mature: 26894

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTASSPATHVRRTQSLADVVVDHIKGRIANESLRIGDKLPTESALMEALGVSRTVIREA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHCCHHHHHHHH
ISRLQAKGMIETRHGIGSFVLPPRADNSIPLGDASTMHDILSMLELRVAIETECAGLAAQ
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISPTEIDALRLALEAIEQDQADGNDSATSDLQFHLSIARATGNEHFVGALAQLGKTLIP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEHHCCCHHHHHHHHHHHHHHCC
RTRIGLAQVGYLNAPELRATVNREHHSVFEAIARKDPEAARAAMRMHLSNSRERLRRAHE
HHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAGTQSAATGS
HCCCCCCCCCC
>Mature Secondary Structure 
PTASSPATHVRRTQSLADVVVDHIKGRIANESLRIGDKLPTESALMEALGVSRTVIREA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHCCHHHHHHHH
ISRLQAKGMIETRHGIGSFVLPPRADNSIPLGDASTMHDILSMLELRVAIETECAGLAAQ
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISPTEIDALRLALEAIEQDQADGNDSATSDLQFHLSIARATGNEHFVGALAQLGKTLIP
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEHHCCCHHHHHHHHHHHHHHCC
RTRIGLAQVGYLNAPELRATVNREHHSVFEAIARKDPEAARAAMRMHLSNSRERLRRAHE
HHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AAGTQSAATGS
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]