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The map label for this gene is efp

Identifier: 187928029

GI number: 187928029

Start: 986959

End: 987534

Strand: Reverse

Name: efp

Synonym: Rpic_0934

Alternate gene names: 187928029

Gene position: 987534-986959 (Counterclockwise)

Preceding gene: 187928030

Following gene: 187928006

Centisome position: 25.05

GC content: 57.29

Gene sequence:

>576_bases
ATGGCTTTGAAAATCGCGCAAGAACTTCGCGCTGGCAACGTGTTCATGATCGGCAACGACGCAATGGTCGTGCTCAAGAC
CGAGTACAGCCGTTCGGGCCGTTCGGGCGCCGTCGTCAAGATGAAGTACAAGAACCTGCTGACCGGCGCAGGCGGCGAGT
CGGTGTTCAACGCCGACGACAAGATGGACCAGGTCATCCTGGAGAAGAAGGAAGCCGAGTACTCCTACTTCGACGGCACG
ATGTACGTGTTCATGGATCCGGTCACCTACGAACAATACAACGTTGAGCCCGCCGCCATGGGCAGCGCGTTGAACTACCT
GCAAGACGGCATGAAGGTCGAAGTGACGTTCTACAACGAGAACGCCATCTCGGTGGAACTGCCGACCACGGTTGTCCGCG
AAATCGTCTACACCGAACCGGCTGTCAAGGGCGACACGTCGTCGGGTAAGGTTCTGAAGGCGGCTCGCATCAACGACAAC
GAAGAATTCACGATCATGGTCCCGCTGTTCTGCAACATCGGCGAGAAGATCGAAATCGACACGCGTACCGACGAGTACCG
CAGCCGCGCCAAGTAA

Upstream 100 bases:

>100_bases
CGACCCCCGGCTCTGACCTGGTTCGCGCGGCCCGGAGGGTATCGCGCGGTGCTTCGTTGCTTGGCGCGCATCGAACCCTC
TTACTCTCAGGAAATGTGAA

Downstream 100 bases:

>100_bases
GAGCTGGCGTCGCAGCAAGCAGAAAGGCTCCCTCGGGAGCCTTTTCTTTTGCGATCGCGTTTTTGCGTTTTGGCGCTACG
CGATGAGTTTCGCCTCGCGC

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MALKIAQELRAGNVFMIGNDAMVVLKTEYSRSGRSGAVVKMKYKNLLTGAGGESVFNADDKMDQVILEKKEAEYSYFDGT
MYVFMDPVTYEQYNVEPAAMGSALNYLQDGMKVEVTFYNENAISVELPTTVVREIVYTEPAVKGDTSSGKVLKAARINDN
EEFTIMVPLFCNIGEKIEIDTRTDEYRSRAK

Sequences:

>Translated_191_residues
MALKIAQELRAGNVFMIGNDAMVVLKTEYSRSGRSGAVVKMKYKNLLTGAGGESVFNADDKMDQVILEKKEAEYSYFDGT
MYVFMDPVTYEQYNVEPAAMGSALNYLQDGMKVEVTFYNENAISVELPTTVVREIVYTEPAVKGDTSSGKVLKAARINDN
EEFTIMVPLFCNIGEKIEIDTRTDEYRSRAK
>Mature_190_residues
ALKIAQELRAGNVFMIGNDAMVVLKTEYSRSGRSGAVVKMKYKNLLTGAGGESVFNADDKMDQVILEKKEAEYSYFDGTM
YVFMDPVTYEQYNVEPAAMGSALNYLQDGMKVEVTFYNENAISVELPTTVVREIVYTEPAVKGDTSSGKVLKAARINDNE
EFTIMVPLFCNIGEKIEIDTRTDEYRSRAK

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=191, Percent_Identity=35.0785340314136, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=30.6878306878307, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_RALPJ (B2U987)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898516.1
- ProteinModelPortal:   B2U987
- SMR:   B2U987
- GeneID:   6288709
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0934
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21369; Mature: 21237

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKIAQELRAGNVFMIGNDAMVVLKTEYSRSGRSGAVVKMKYKNLLTGAGGESVFNADD
CCEEEHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEHHEECCCCCCCEECCCC
KMDQVILEKKEAEYSYFDGTMYVFMDPVTYEQYNVEPAAMGSALNYLQDGMKVEVTFYNE
HHHHHHHHHCCCCEEEECCEEEEEECCEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECC
NAISVELPTTVVREIVYTEPAVKGDTSSGKVLKAARINDNEEFTIMVPLFCNIGEKIEID
CEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEE
TRTDEYRSRAK
CCCHHHHHCCC
>Mature Secondary Structure 
ALKIAQELRAGNVFMIGNDAMVVLKTEYSRSGRSGAVVKMKYKNLLTGAGGESVFNADD
CEEEHHHHCCCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEHHEECCCCCCCEECCCC
KMDQVILEKKEAEYSYFDGTMYVFMDPVTYEQYNVEPAAMGSALNYLQDGMKVEVTFYNE
HHHHHHHHHCCCCEEEECCEEEEEECCEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECC
NAISVELPTTVVREIVYTEPAVKGDTSSGKVLKAARINDNEEFTIMVPLFCNIGEKIEID
CEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEE
TRTDEYRSRAK
CCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA