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The map label for this gene is rbsK [H]

Identifier: 187927973

GI number: 187927973

Start: 932049

End: 933014

Strand: Reverse

Name: rbsK [H]

Synonym: Rpic_0878

Alternate gene names: 187927973

Gene position: 933014-932049 (Counterclockwise)

Preceding gene: 187927974

Following gene: 187927970

Centisome position: 23.67

GC content: 69.15

Gene sequence:

>966_bases
ATGGTGGCCAAGCGCCCTTCCGCCTCTTCCGCGCACCCCGCTGCCGACGTGCTGATCGTCGGCAGCCTGAATATGGATCT
CGTGATCCGCACGCCCCGCTTGCCGCGTCCCAGGCAAACGGTTGCAGCGCCTGCGCTGGAAACCATCCCGGGCGGCAAGG
GCGCCAACCAGGCAGTGGCCGCTGCACGCCTGGGGGCCCGTGTCGCCATGCTCGGCTGCGTGGGTGATGACGCGTACGGC
ACCGCGCTGCGCGACGGCCTGCGCCGCGAAGGCGTGGACACATCGATGGTGTCGGAGCACGCCGGGGTGGCCACCGGCAT
CGCCTGCGTGACCGTGGCCAACAGCGGCCAGAACACCATCGTCATCGTGGCCGGCGCCAACGAGTTGCTGACGCCAACGA
TGATCGAAGCCCAGCGTGCTGCGTTCGAACGCGCGCGCGTCATCGTCTGTCAGTTGGAATCGCCGCCCGATGCGGTGGAA
TGCGCCCTCAAGCTGGGCCAGCGGCTTGGCAAGACGGTCATCCTGAACCCTGCACCCGCCATCGGCCCCTTGCCTACGCC
GTGGATCGCCGCCTGCGATTACCTGATCCCGAACGAAACCGAAGCCGCGCTGCTGACGGCCCGGCCAGTCGATTCGCCCG
AAGCCGCACTGGATGCCGCTGCCGATCTCCACGCACAAGGTGCGCGGCACGTGATTGTCACGCTGGGCGCGCACGGCGTT
GCCTACGTGGATGCCCACTCGCGCCTGCTGATGCCGGCGCCCACCGCGCATGCCATCGATACCACTGCCGCTGGCGATAC
GTTCGTGGGTGCGCTGGCAGCGGCATTGGCGGAAGACGCGGCAGCCGATGCAGCCATCGAGTTTGGGCAAGCCGCGGCGG
CCGTGTCAGTCACGCGGCTCGGCGCGCAGCCGTCCATTCCGTTCCGCAGCGAGCTGGGTGCGCCTGCCGCGCCTGCCACC
CACTAG

Upstream 100 bases:

>100_bases
CCGCCGCGCCTGTCTTTGCGCGAGTCGACCGCCGAGCCCGAGCGCCCCGCCCGCGCCGCCTGATCCCGCATCCCTTTCAC
GCTTTCAACGTAGTCCCGCC

Downstream 100 bases:

>100_bases
ACCGGCGTACTGGTGCCGGGCGGCGTGCTCGCGGTCGGGGCGCGCGGTACCAGCAGGCAAAGCGGATCCCGCAAGATGCG
CCGCCACACGGCACCCGTCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MVAKRPSASSAHPAADVLIVGSLNMDLVIRTPRLPRPRQTVAAPALETIPGGKGANQAVAAARLGARVAMLGCVGDDAYG
TALRDGLRREGVDTSMVSEHAGVATGIACVTVANSGQNTIVIVAGANELLTPTMIEAQRAAFERARVIVCQLESPPDAVE
CALKLGQRLGKTVILNPAPAIGPLPTPWIAACDYLIPNETEAALLTARPVDSPEAALDAAADLHAQGARHVIVTLGAHGV
AYVDAHSRLLMPAPTAHAIDTTAAGDTFVGALAAALAEDAAADAAIEFGQAAAAVSVTRLGAQPSIPFRSELGAPAAPAT
H

Sequences:

>Translated_321_residues
MVAKRPSASSAHPAADVLIVGSLNMDLVIRTPRLPRPRQTVAAPALETIPGGKGANQAVAAARLGARVAMLGCVGDDAYG
TALRDGLRREGVDTSMVSEHAGVATGIACVTVANSGQNTIVIVAGANELLTPTMIEAQRAAFERARVIVCQLESPPDAVE
CALKLGQRLGKTVILNPAPAIGPLPTPWIAACDYLIPNETEAALLTARPVDSPEAALDAAADLHAQGARHVIVTLGAHGV
AYVDAHSRLLMPAPTAHAIDTTAAGDTFVGALAAALAEDAAADAAIEFGQAAAAVSVTRLGAQPSIPFRSELGAPAAPAT
H
>Mature_321_residues
MVAKRPSASSAHPAADVLIVGSLNMDLVIRTPRLPRPRQTVAAPALETIPGGKGANQAVAAARLGARVAMLGCVGDDAYG
TALRDGLRREGVDTSMVSEHAGVATGIACVTVANSGQNTIVIVAGANELLTPTMIEAQRAAFERARVIVCQLESPPDAVE
CALKLGQRLGKTVILNPAPAIGPLPTPWIAACDYLIPNETEAALLTARPVDSPEAALDAAADLHAQGARHVIVTLGAHGV
AYVDAHSRLLMPAPTAHAIDTTAAGDTFVGALAAALAEDAAADAAIEFGQAAAAVSVTRLGAQPSIPFRSELGAPAAPAT
H

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=300, Percent_Identity=39.6666666666667, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI1790193, Length=302, Percent_Identity=44.0397350993377, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1788484, Length=283, Percent_Identity=27.208480565371, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082343, Length=292, Percent_Identity=30.1369863013699, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788491, Length=289, Percent_Identity=24.5674740484429, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788017, Length=295, Percent_Identity=27.4576271186441, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=295, Percent_Identity=36.271186440678, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=30.421686746988, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6322565, Length=293, Percent_Identity=26.6211604095563, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=37.5415282392027, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24583886, Length=299, Percent_Identity=34.4481605351171, Blast_Score=160, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32520; Mature: 32520

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAKRPSASSAHPAADVLIVGSLNMDLVIRTPRLPRPRQTVAAPALETIPGGKGANQAVA
CCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHCCHHHHCCCCCCCHHHHH
AARLGARVAMLGCVGDDAYGTALRDGLRREGVDTSMVSEHAGVATGIACVTVANSGQNTI
HHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHCEEEEEEECCCCCEE
VIVAGANELLTPTMIEAQRAAFERARVIVCQLESPPDAVECALKLGQRLGKTVILNPAPA
EEEECCCHHCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHCCEEEECCCCC
IGPLPTPWIAACDYLIPNETEAALLTARPVDSPEAALDAAADLHAQGARHVIVTLGAHGV
CCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCE
AYVDAHSRLLMPAPTAHAIDTTAAGDTFVGALAAALAEDAAADAAIEFGQAAAAVSVTRL
EEEECCCEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAQPSIPFRSELGAPAAPATH
CCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MVAKRPSASSAHPAADVLIVGSLNMDLVIRTPRLPRPRQTVAAPALETIPGGKGANQAVA
CCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHCCHHHHCCCCCCCHHHHH
AARLGARVAMLGCVGDDAYGTALRDGLRREGVDTSMVSEHAGVATGIACVTVANSGQNTI
HHHHCCEEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHCEEEEEEECCCCCEE
VIVAGANELLTPTMIEAQRAAFERARVIVCQLESPPDAVECALKLGQRLGKTVILNPAPA
EEEECCCHHCCHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHCCEEEECCCCC
IGPLPTPWIAACDYLIPNETEAALLTARPVDSPEAALDAAADLHAQGARHVIVTLGAHGV
CCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCE
AYVDAHSRLLMPAPTAHAIDTTAAGDTFVGALAAALAEDAAADAAIEFGQAAAAVSVTRL
EEEECCCEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAQPSIPFRSELGAPAAPATH
CCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]