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The map label for this gene is aspC [H]

Identifier: 187927970

GI number: 187927970

Start: 926170

End: 927366

Strand: Reverse

Name: aspC [H]

Synonym: Rpic_0875

Alternate gene names: 187927970

Gene position: 927366-926170 (Counterclockwise)

Preceding gene: 187927973

Following gene: 187927969

Centisome position: 23.52

GC content: 64.08

Gene sequence:

>1197_bases
ATGTCGCTTTTCTCCGCCGTCGAACTGGCCCCGCGCGACCCCATCCTGGGCCTGAATGAAGCTTTCAACGCCGATACCCG
CAGCACCAAAGTGAATCTGGGCGTGGGCGTGTACTTCACCGACGAAGGGAAAATTCCGGTGCTGCGCGCCGTGCAGGAAG
CCGAAAAGGCCCGCCTGGCTGCCGCTGCCCCGCGTGGCTACCTGCCGATCGAAGGCATTGCCGCCTACGACCAGGCCGTG
CAGAAGCTGCTGTTCGGCGCGGAATCGCCGCTCATCACCGAAGGCCGCGTGGTCACCGCGCAAGCCCTGGGCGGCACCGG
CGCACTGAAGATCGGCGCCGACTTCCTCAAGCGCCTGTACCCGAACGCCAAAGTCGCGATTTCCGACCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAATCCGCCGGTTTCGAAGTGGTCAACTACGCGTACTACGATGCCCCGTCGCACGGCCTGAAC
TTCGCCGGCATGCTGGATTCGCTGAACGGCTACGCGCCGAACACGATCGTCGTGCTGCACGCCTGCTGCCACAACCCGAC
CGGCGTGGACATGACCACCGAGCAGTGGAAGCAGGTCGTGGAAGTCATCAAGGCCAAGAACCTGATCCCGTTCCTCGACA
TGGCTTACCAAGGCTTCGCCGACGGCATCCAGCAAGACGGCCTGGCTGTGCGCCTGTTTGCTGAATCGGGCCTGCCGTTC
TTCGTCTCCAGCTCGTTCTCGAAGTCGTTCTCGCTCTACGGCGAGCGCGTCGGCGCGCTGTCGATCGTGACGACCAGCAA
GGACGAATCCGCCCGCGTGCTGTCGCAAGTCAAGCGCGTGATCCGCACGAACTACTCGAACCCGCCGACGCATGGCGGCA
CGATCGTCGCCAGCGTGCTGACGAGCCCCGAGCTGCGCGCGATGTGGGAGCAGGAGCTGGGCGAAATGCGCGATCGCATC
AAGTCGATGCGCAACGCGCTGGTCGACAAGCTGGCCGCAAAGGGCGTGAAGACCGATTTCTCGTTCGTGAAGGCCCAGCG
CGGCATGTTCTCGTACTCGGGCCTGACCTCCGCGCAAGTGGATCGCCTGCGCACCGAGCACGGCATCTACGCCGTGTCGA
CCGGCCGCATCTGCGTGGCCGCGCTGAACACGCACAACATCGATGCCGTGGTGAATGCCATCGCTGATGTTCTGTAA

Upstream 100 bases:

>100_bases
GCCTCGTTGTACATCTGGCGCCGGGCGAGCCGCCCCGGAGTCCGCGCCGCACCGCCTGCAAGATCCCACCGAATCCCGAA
CCAACCGATCGAGACATCTC

Downstream 100 bases:

>100_bases
AGGTGCTGTAGGCATCACGCCTTAGGTGCAATTGCAAAAAGAAAAGCGGCTTCGGCCGCTTTTTTGCTGCATCGGAATAG
ACTGACACGGGCGCATCATA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLFSAVELAPRDPILGLNEAFNADTRSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLAAAAPRGYLPIEGIAAYDQAV
QKLLFGAESPLITEGRVVTAQALGGTGALKIGADFLKRLYPNAKVAISDPSWENHRALFESAGFEVVNYAYYDAPSHGLN
FAGMLDSLNGYAPNTIVVLHACCHNPTGVDMTTEQWKQVVEVIKAKNLIPFLDMAYQGFADGIQQDGLAVRLFAESGLPF
FVSSSFSKSFSLYGERVGALSIVTTSKDESARVLSQVKRVIRTNYSNPPTHGGTIVASVLTSPELRAMWEQELGEMRDRI
KSMRNALVDKLAAKGVKTDFSFVKAQRGMFSYSGLTSAQVDRLRTEHGIYAVSTGRICVAALNTHNIDAVVNAIADVL

Sequences:

>Translated_398_residues
MSLFSAVELAPRDPILGLNEAFNADTRSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLAAAAPRGYLPIEGIAAYDQAV
QKLLFGAESPLITEGRVVTAQALGGTGALKIGADFLKRLYPNAKVAISDPSWENHRALFESAGFEVVNYAYYDAPSHGLN
FAGMLDSLNGYAPNTIVVLHACCHNPTGVDMTTEQWKQVVEVIKAKNLIPFLDMAYQGFADGIQQDGLAVRLFAESGLPF
FVSSSFSKSFSLYGERVGALSIVTTSKDESARVLSQVKRVIRTNYSNPPTHGGTIVASVLTSPELRAMWEQELGEMRDRI
KSMRNALVDKLAAKGVKTDFSFVKAQRGMFSYSGLTSAQVDRLRTEHGIYAVSTGRICVAALNTHNIDAVVNAIADVL
>Mature_397_residues
SLFSAVELAPRDPILGLNEAFNADTRSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLAAAAPRGYLPIEGIAAYDQAVQ
KLLFGAESPLITEGRVVTAQALGGTGALKIGADFLKRLYPNAKVAISDPSWENHRALFESAGFEVVNYAYYDAPSHGLNF
AGMLDSLNGYAPNTIVVLHACCHNPTGVDMTTEQWKQVVEVIKAKNLIPFLDMAYQGFADGIQQDGLAVRLFAESGLPFF
VSSSFSKSFSLYGERVGALSIVTTSKDESARVLSQVKRVIRTNYSNPPTHGGTIVASVLTSPELRAMWEQELGEMRDRIK
SMRNALVDKLAAKGVKTDFSFVKAQRGMFSYSGLTSAQVDRLRTEHGIYAVSTGRICVAALNTHNIDAVVNAIADVL

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=43.9393939393939, Blast_Score=347, Evalue=2e-95,
Organism=Homo sapiens, GI4504067, Length=405, Percent_Identity=43.4567901234568, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI117414139, Length=403, Percent_Identity=29.0322580645161, Blast_Score=179, Evalue=6e-45,
Organism=Escherichia coli, GI1790488, Length=399, Percent_Identity=51.3784461152882, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=47.979797979798, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71981858, Length=398, Percent_Identity=43.21608040201, Blast_Score=356, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=42.3173803526448, Blast_Score=337, Evalue=5e-93,
Organism=Caenorhabditis elegans, GI17569539, Length=402, Percent_Identity=42.2885572139304, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17569537, Length=402, Percent_Identity=34.5771144278607, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17550384, Length=268, Percent_Identity=36.5671641791045, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=40.3755868544601, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=39.9014778325123, Blast_Score=317, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6322743, Length=434, Percent_Identity=32.0276497695853, Blast_Score=241, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=42.2110552763819, Blast_Score=334, Evalue=5e-92,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=42.2110552763819, Blast_Score=334, Evalue=6e-92,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=42.1994884910486, Blast_Score=327, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24654046, Length=397, Percent_Identity=41.3098236775819, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI19922362, Length=397, Percent_Identity=41.3098236775819, Blast_Score=315, Evalue=5e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43046; Mature: 42914

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVELAPRDPILGLNEAFNADTRSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLA
CCCHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHH
AAAPRGYLPIEGIAAYDQAVQKLLFGAESPLITEGRVVTAQALGGTGALKIGADFLKRLY
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEEEEEECCCCCEEHHHHHHHHHHC
PNAKVAISDPSWENHRALFESAGFEVVNYAYYDAPSHGLNFAGMLDSLNGYAPNTIVVLH
CCCEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEEE
ACCHNPTGVDMTTEQWKQVVEVIKAKNLIPFLDMAYQGFADGIQQDGLAVRLFAESGLPF
EHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCE
FVSSSFSKSFSLYGERVGALSIVTTSKDESARVLSQVKRVIRTNYSNPPTHGGTIVASVL
EEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
TSPELRAMWEQELGEMRDRIKSMRNALVDKLAAKGVKTDFSFVKAQRGMFSYSGLTSAQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
DRLRTEHGIYAVSTGRICVAALNTHNIDAVVNAIADVL
HHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVELAPRDPILGLNEAFNADTRSTKVNLGVGVYFTDEGKIPVLRAVQEAEKARLA
CCHHHHHCCCCCCCCCCHHHCCCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHH
AAAPRGYLPIEGIAAYDQAVQKLLFGAESPLITEGRVVTAQALGGTGALKIGADFLKRLY
HCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCEEEEEEECCCCCEEHHHHHHHHHHC
PNAKVAISDPSWENHRALFESAGFEVVNYAYYDAPSHGLNFAGMLDSLNGYAPNTIVVLH
CCCEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEEE
ACCHNPTGVDMTTEQWKQVVEVIKAKNLIPFLDMAYQGFADGIQQDGLAVRLFAESGLPF
EHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCE
FVSSSFSKSFSLYGERVGALSIVTTSKDESARVLSQVKRVIRTNYSNPPTHGGTIVASVL
EEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
TSPELRAMWEQELGEMRDRIKSMRNALVDKLAAKGVKTDFSFVKAQRGMFSYSGLTSAQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHH
DRLRTEHGIYAVSTGRICVAALNTHNIDAVVNAIADVL
HHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]