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The map label for this gene is kdgR [H]

Identifier: 187927789

GI number: 187927789

Start: 731349

End: 732413

Strand: Direct

Name: kdgR [H]

Synonym: Rpic_0693

Alternate gene names: 187927789

Gene position: 731349-732413 (Clockwise)

Preceding gene: 187927788

Following gene: 187927790

Centisome position: 18.55

GC content: 63.85

Gene sequence:

>1065_bases
GTGACTGATTTCCCATCCTCTTCCTCGCGCCCTGCGACCATCACCGACGTGGCCCGCGAAGCGGGAACCGGCAAGACCAG
CGTGTCCCGCTATCTGAACGGCGAGATGCAGGTCCTTTCCGAAGATTTGCGACAGCGCATCGAAGCCGCCATCCAGCGGT
TGAACTACCGGCCCAACCAGATGGCCCGTGGCCTCAAGCGAGGCCGCAATCGCCTGCTCGGCATGCTGGTGGCCGATCTG
ACCAATCCTTACTCGATCGAAGTCCTGCAAGGCGTTGAAGCCGCTTGCCACGCGCTGGGCTACATGCCGCTCATCTGCCA
CGCCGCCAATGAGATCGAGATGGAGCGCCGCTTCGTCCAGTTGCTGACGACGTACCGGGTCGAAGGTTTGATCGTCAACG
CGCTCGGCGCGGAAGAGGCCGTATTGCGCCCCTTGCGGGGTGGCGGTATTCCCGCTGTGCTGGTGGATCGCACGGTAGAA
GGGTTCGACGCCGACCTCGTGGGGCTCGATAACCGCGACGCCGTCCGGCTGGGCGTGCAACATCTGCTGGATCACGGTTT
CGATGCCATCCAGTTCATCGTGCAGCCGTTTGAGCAGGTCAGTTCCCGGCGTGAACGCGAACTTGCCTTTCGAGAGGCGA
TGGCAGCGCAAGGGCGGCCAGCGGAGCCGACCGTGGTGCTCGACCCGAACGATCCGGCCTCAACTGAGCGTGCGCTGGCC
GAGATCGATGCACGCATCGATGCGGTGTATCAGCGAGGCGGAAAACGACTCGCGCTGTTTGTTGCCAACGCGCCGGTCGC
GCTCGTCGTTGCGCGGCATCTGCGCACGCAGTTTGGCCCAGCCTGGCAGGAGCGGGCGGCGCTGCTGTCGATCGATGATC
CGGAATGGGCCGAGTTGATCGGCATCACCACGATCCGGCAACCGACGTATGACATCGGCTACAAGGCGGTCGAGTTCGTG
CATGAACGCATCGAAGGCGTGAGCGGGGATGCCCGTGTCGTGTTGCTGCCCGGCACGCTGGTCGAACGTGCTTCGACGGT
GCATTCGACGCAGGCCGCGTCATGA

Upstream 100 bases:

>100_bases
GAGCCCACCCGCGCCTCATGAGCCGAGTGCCGGGATTGCGCTATGATCCTCGCACTCCGGCTTCGGCCCCTCGTGCCGAC
GGCCTGCTCTGAAGCGCAAC

Downstream 100 bases:

>100_bases
CGTTGCGTCTGTATCTCGCGGGGCCGGACGTTTTTCGTCCGGAGCCCATTGCGCACGGCGAGGCGCTCAAGGCGTTGTGC
GCCGAGTTTGGCTTTAGCGG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTDFPSSSSRPATITDVAREAGTGKTSVSRYLNGEMQVLSEDLRQRIEAAIQRLNYRPNQMARGLKRGRNRLLGMLVADL
TNPYSIEVLQGVEAACHALGYMPLICHAANEIEMERRFVQLLTTYRVEGLIVNALGAEEAVLRPLRGGGIPAVLVDRTVE
GFDADLVGLDNRDAVRLGVQHLLDHGFDAIQFIVQPFEQVSSRRERELAFREAMAAQGRPAEPTVVLDPNDPASTERALA
EIDARIDAVYQRGGKRLALFVANAPVALVVARHLRTQFGPAWQERAALLSIDDPEWAELIGITTIRQPTYDIGYKAVEFV
HERIEGVSGDARVVLLPGTLVERASTVHSTQAAS

Sequences:

>Translated_354_residues
MTDFPSSSSRPATITDVAREAGTGKTSVSRYLNGEMQVLSEDLRQRIEAAIQRLNYRPNQMARGLKRGRNRLLGMLVADL
TNPYSIEVLQGVEAACHALGYMPLICHAANEIEMERRFVQLLTTYRVEGLIVNALGAEEAVLRPLRGGGIPAVLVDRTVE
GFDADLVGLDNRDAVRLGVQHLLDHGFDAIQFIVQPFEQVSSRRERELAFREAMAAQGRPAEPTVVLDPNDPASTERALA
EIDARIDAVYQRGGKRLALFVANAPVALVVARHLRTQFGPAWQERAALLSIDDPEWAELIGITTIRQPTYDIGYKAVEFV
HERIEGVSGDARVVLLPGTLVERASTVHSTQAAS
>Mature_353_residues
TDFPSSSSRPATITDVAREAGTGKTSVSRYLNGEMQVLSEDLRQRIEAAIQRLNYRPNQMARGLKRGRNRLLGMLVADLT
NPYSIEVLQGVEAACHALGYMPLICHAANEIEMERRFVQLLTTYRVEGLIVNALGAEEAVLRPLRGGGIPAVLVDRTVEG
FDADLVGLDNRDAVRLGVQHLLDHGFDAIQFIVQPFEQVSSRRERELAFREAMAAQGRPAEPTVVLDPNDPASTERALAE
IDARIDAVYQRGGKRLALFVANAPVALVVARHLRTQFGPAWQERAALLSIDDPEWAELIGITTIRQPTYDIGYKAVEFVH
ERIEGVSGDARVVLLPGTLVERASTVHSTQAAS

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=341, Percent_Identity=29.3255131964809, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789202, Length=235, Percent_Identity=28.936170212766, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790369, Length=351, Percent_Identity=25.3561253561254, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787948, Length=342, Percent_Identity=27.7777777777778, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788474, Length=349, Percent_Identity=26.0744985673352, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994940, Length=188, Percent_Identity=32.4468085106383, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=352, Percent_Identity=24.1477272727273, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786540, Length=359, Percent_Identity=26.7409470752089, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790689, Length=205, Percent_Identity=27.3170731707317, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786268, Length=170, Percent_Identity=28.8235294117647, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787580, Length=214, Percent_Identity=26.6355140186916, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789068, Length=286, Percent_Identity=24.1258741258741, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790715, Length=163, Percent_Identity=29.4478527607362, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38896; Mature: 38765

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFPSSSSRPATITDVAREAGTGKTSVSRYLNGEMQVLSEDLRQRIEAAIQRLNYRPNQ
CCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
MARGLKRGRNRLLGMLVADLTNPYSIEVLQGVEAACHALGYMPLICHAANEIEMERRFVQ
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LLTTYRVEGLIVNALGAEEAVLRPLRGGGIPAVLVDRTVEGFDADLVGLDNRDAVRLGVQ
HHHHHHHHHEEEECCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHH
HLLDHGFDAIQFIVQPFEQVSSRRERELAFREAMAAQGRPAEPTVVLDPNDPASTERALA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHH
EIDARIDAVYQRGGKRLALFVANAPVALVVARHLRTQFGPAWQERAALLSIDDPEWAELI
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHCCEEEECCCCHHHHHH
GITTIRQPTYDIGYKAVEFVHERIEGVSGDARVVLLPGTLVERASTVHSTQAAS
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDFPSSSSRPATITDVAREAGTGKTSVSRYLNGEMQVLSEDLRQRIEAAIQRLNYRPNQ
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHH
MARGLKRGRNRLLGMLVADLTNPYSIEVLQGVEAACHALGYMPLICHAANEIEMERRFVQ
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LLTTYRVEGLIVNALGAEEAVLRPLRGGGIPAVLVDRTVEGFDADLVGLDNRDAVRLGVQ
HHHHHHHHHEEEECCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCEECCCCCHHHHHHHH
HLLDHGFDAIQFIVQPFEQVSSRRERELAFREAMAAQGRPAEPTVVLDPNDPASTERALA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHH
EIDARIDAVYQRGGKRLALFVANAPVALVVARHLRTQFGPAWQERAALLSIDDPEWAELI
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHCCEEEECCCCHHHHHH
GITTIRQPTYDIGYKAVEFVHERIEGVSGDARVVLLPGTLVERASTVHSTQAAS
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]