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The map label for this gene is qseC [H]

Identifier: 187927672

GI number: 187927672

Start: 608749

End: 610125

Strand: Direct

Name: qseC [H]

Synonym: Rpic_0576

Alternate gene names: 187927672

Gene position: 608749-610125 (Clockwise)

Preceding gene: 187927671

Following gene: 187927673

Centisome position: 15.44

GC content: 63.04

Gene sequence:

>1377_bases
ATGACGCGACCGCGCTCGCTCCAAGGTCGGCTGGTGTTGTTGGTGCTTGGCGCCGTCGCCGGCCTATGGCTCATCACCGC
ATTGATCACGTGGTACGACGCCCAGGACGAGATCGATCAACTGCTGGACAGTCATCTAGCGCAAGCTGGTGCGCTACTGG
TCATGCAGCACGCACAGGCCGTCGACGAGGACGATGAGCCGAGTCACGACCTGCCTGTCCAGCATCGTTACGCGCCCAAA
GTCGCCTTTCAGGTCTTTCACGAAGGGAAGCTGGGCATCCACTCGGCCAACGCGCCGAACCAGCCGATGGTTGCGCCAGG
CGAGCGCACCGCGTCCGGATTCTCTACGGTGCAAATCGGAGGCAATGCTTGGCGTGTCTTTGTAGCGCAGGGAGTCTACA
AGGACATCCAGGTCTACGTTGGCGAGCGCATCGACTCGCGCACCGCAATCCTGTCCGCCCTCTTGCGCAACATGCTGTGG
CCGATGGCGTTGGCGTTGCCGTTACTCGCCTTGGCCGTCTGGTGGGCGGTCAAGCGCGGGATGCTGCCGCTGCGCAGATT
GGGTAACGCGCTTGCCGAGCGTGACCCGCGAGCACTCGATCCGGTCCGGATGCCCCATGCGCCGGTTGAGATGACGCCCA
TGCTCGACGCGCTCAACGCGCTCTTTGCCCGCATTCAGACCATGCTCGACGCCGAGCGCCGCTTCACTGCCGACGCCGCC
CACGAATTGCGCACGCCGATTGCCGCAATCAAGGCCCAGGCCCAGGTGGCAATGGCCGCCGAAGAGGACGCCATGCGTCG
CCACGCCTTGGTGGGAACGTTGGAAGGATGCGATCGCGCTGCCCATCTGGTCGACCAATTGCTGTTGCTTTCGCGTCTGG
AAGCGAACGCCGGCATTTCGATTGAACCGATCGACCTTGGTGCGCTGGCTAGACAAGTGATGGCAGACATTGCGCCAATA
GCCTTCGGCAAGAAACAGCGCATCGCACTAGAGAATCCGGAGCGCTGCATGGTCGCGGGCAACAGGGCGTTACTGGCCTC
ACTTGTTCGCAACCTGATCGACAACGCCATACGCTACAGCCCCGCCGAGGCACAAATCGTCGTGACGGTCGCGCACCGTA
ACGGAAGTGCCGCGCTTTGTGTGGAAGACAGCGGCCCCGGACTCCCCGCCGCCGAACAGCACCGACTTGGCGAGCGCTTT
TTCCGTGTCGAGGGAACGGACCAGAGTGGTAGCGGCCTTGGATGGTCGATCGTGCACCGGATCGCGGCGGTTCACGGTGC
AAGCGTAACGGTTGACCGCTCGCCGGGTCTCGGGGGATTGCGCGTCGACGTTATCTGGTCGAACCTCACATCCAGTGGGT
CCGGAACCCACCAATAG

Upstream 100 bases:

>100_bases
AGGTGCATATCCATCATCTGCGCGTCAAACTTGGCAGCGACCTCATCGTGACCGTGCGCGGCGTCGGCTATATGCTGCCG
CGTGACAATGCCGAAGCGCC

Downstream 100 bases:

>100_bases
GTCATGCGCGACTTCATCCCTTCATTGAAGTCATGAAGAATACGAGCCAGCGGTGCGACTCGGGGAGCGTCCCGATGTGG
AAAACGGCTCCGGTCTCTCT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTRPRSLQGRLVLLVLGAVAGLWLITALITWYDAQDEIDQLLDSHLAQAGALLVMQHAQAVDEDDEPSHDLPVQHRYAPK
VAFQVFHEGKLGIHSANAPNQPMVAPGERTASGFSTVQIGGNAWRVFVAQGVYKDIQVYVGERIDSRTAILSALLRNMLW
PMALALPLLALAVWWAVKRGMLPLRRLGNALAERDPRALDPVRMPHAPVEMTPMLDALNALFARIQTMLDAERRFTADAA
HELRTPIAAIKAQAQVAMAAEEDAMRRHALVGTLEGCDRAAHLVDQLLLLSRLEANAGISIEPIDLGALARQVMADIAPI
AFGKKQRIALENPERCMVAGNRALLASLVRNLIDNAIRYSPAEAQIVVTVAHRNGSAALCVEDSGPGLPAAEQHRLGERF
FRVEGTDQSGSGLGWSIVHRIAAVHGASVTVDRSPGLGGLRVDVIWSNLTSSGSGTHQ

Sequences:

>Translated_458_residues
MTRPRSLQGRLVLLVLGAVAGLWLITALITWYDAQDEIDQLLDSHLAQAGALLVMQHAQAVDEDDEPSHDLPVQHRYAPK
VAFQVFHEGKLGIHSANAPNQPMVAPGERTASGFSTVQIGGNAWRVFVAQGVYKDIQVYVGERIDSRTAILSALLRNMLW
PMALALPLLALAVWWAVKRGMLPLRRLGNALAERDPRALDPVRMPHAPVEMTPMLDALNALFARIQTMLDAERRFTADAA
HELRTPIAAIKAQAQVAMAAEEDAMRRHALVGTLEGCDRAAHLVDQLLLLSRLEANAGISIEPIDLGALARQVMADIAPI
AFGKKQRIALENPERCMVAGNRALLASLVRNLIDNAIRYSPAEAQIVVTVAHRNGSAALCVEDSGPGLPAAEQHRLGERF
FRVEGTDQSGSGLGWSIVHRIAAVHGASVTVDRSPGLGGLRVDVIWSNLTSSGSGTHQ
>Mature_457_residues
TRPRSLQGRLVLLVLGAVAGLWLITALITWYDAQDEIDQLLDSHLAQAGALLVMQHAQAVDEDDEPSHDLPVQHRYAPKV
AFQVFHEGKLGIHSANAPNQPMVAPGERTASGFSTVQIGGNAWRVFVAQGVYKDIQVYVGERIDSRTAILSALLRNMLWP
MALALPLLALAVWWAVKRGMLPLRRLGNALAERDPRALDPVRMPHAPVEMTPMLDALNALFARIQTMLDAERRFTADAAH
ELRTPIAAIKAQAQVAMAAEEDAMRRHALVGTLEGCDRAAHLVDQLLLLSRLEANAGISIEPIDLGALARQVMADIAPIA
FGKKQRIALENPERCMVAGNRALLASLVRNLIDNAIRYSPAEAQIVVTVAHRNGSAALCVEDSGPGLPAAEQHRLGERFF
RVEGTDQSGSGLGWSIVHRIAAVHGASVTVDRSPGLGGLRVDVIWSNLTSSGSGTHQ

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=455, Percent_Identity=33.8461538461538, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1786783, Length=302, Percent_Identity=27.4834437086093, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=31.6151202749141, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788279, Length=315, Percent_Identity=26.6666666666667, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=280, Percent_Identity=27.5, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790861, Length=281, Percent_Identity=26.6903914590747, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787894, Length=250, Percent_Identity=30.4, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.4518828451883, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.099173553719, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787374, Length=285, Percent_Identity=22.8070175438596, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=27.3972602739726, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=23.6514522821577, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=213, Percent_Identity=25.3521126760563, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=25.8741258741259, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=215, Percent_Identity=24.6511627906977, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081816, Length=220, Percent_Identity=25.4545454545455, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49528; Mature: 49396

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPRSLQGRLVLLVLGAVAGLWLITALITWYDAQDEIDQLLDSHLAQAGALLVMQHAQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VDEDDEPSHDLPVQHRYAPKVAFQVFHEGKLGIHSANAPNQPMVAPGERTASGFSTVQIG
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEC
GNAWRVFVAQGVYKDIQVYVGERIDSRTAILSALLRNMLWPMALALPLLALAVWWAVKRG
CCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MLPLRRLGNALAERDPRALDPVRMPHAPVEMTPMLDALNALFARIQTMLDAERRFTADAA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPIAAIKAQAQVAMAAEEDAMRRHALVGTLEGCDRAAHLVDQLLLLSRLEANAGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IEPIDLGALARQVMADIAPIAFGKKQRIALENPERCMVAGNRALLASLVRNLIDNAIRYS
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCC
PAEAQIVVTVAHRNGSAALCVEDSGPGLPAAEQHRLGERFFRVEGTDQSGSGLGWSIVHR
CCCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCHHHHHH
IAAVHGASVTVDRSPGLGGLRVDVIWSNLTSSGSGTHQ
HHHHCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TRPRSLQGRLVLLVLGAVAGLWLITALITWYDAQDEIDQLLDSHLAQAGALLVMQHAQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VDEDDEPSHDLPVQHRYAPKVAFQVFHEGKLGIHSANAPNQPMVAPGERTASGFSTVQIG
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEC
GNAWRVFVAQGVYKDIQVYVGERIDSRTAILSALLRNMLWPMALALPLLALAVWWAVKRG
CCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MLPLRRLGNALAERDPRALDPVRMPHAPVEMTPMLDALNALFARIQTMLDAERRFTADAA
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HELRTPIAAIKAQAQVAMAAEEDAMRRHALVGTLEGCDRAAHLVDQLLLLSRLEANAGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IEPIDLGALARQVMADIAPIAFGKKQRIALENPERCMVAGNRALLASLVRNLIDNAIRYS
EECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCC
PAEAQIVVTVAHRNGSAALCVEDSGPGLPAAEQHRLGERFFRVEGTDQSGSGLGWSIVHR
CCCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCHHHHHH
IAAVHGASVTVDRSPGLGGLRVDVIWSNLTSSGSGTHQ
HHHHCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]