Click here to switch to the map view.

The map label for this gene is qseB [H]

Identifier: 187927671

GI number: 187927671

Start: 608078

End: 608752

Strand: Direct

Name: qseB [H]

Synonym: Rpic_0575

Alternate gene names: 187927671

Gene position: 608078-608752 (Clockwise)

Preceding gene: 187927670

Following gene: 187927672

Centisome position: 15.42

GC content: 65.04

Gene sequence:

>675_bases
GTGCGCATCCTGCTTGTCGAAGACGACCCCCTGCTCGGAGACGGCATTCGTGCGGGCCTGCAGCAGCAGGGCTTCCAGGT
CGATTGGGTGCGCGACGGCGAGGCAGCGTGGCGGGAGTTGCGCACGGACGCCTACGTCGCCGCAATACTCGACCTTGGGC
TGCCCCGCATGGACGGCGTGGACGTGCTGCGAAAGGTGCGTGGCGCAGGCATTGCGGTCCCCATCCTGGTGTTGACCGCG
CGCGACGCGATACCAGATCGCGTGCGTGGTCTCGATCTCGGCGCCGATGATTACATCGTCAAGCCCATTGATCTGCACGA
ACTCAGCGCGAGACTGCGCGCGCTGGTGCGCCGCGCGCATGGTCATCCCACGGAGCAGTTGAGGGCGCGCGGCATTGTTC
TGGAGCCGGCGTCACGCACGGTCTTCTGCAACGGTCGAGCCGTCGCACTGTCGACGCGGGAATTTGACCTGCTGCATGCC
TTGATGCTGAACGCGGGGCGCGTGCTGTCACGTGAGCAGCTCGAGCAGTGCCTATACCCCTGGGGGCAGGAAGTCGGAAG
CAACTCCGTGGAGGTGCATATCCATCATCTGCGCGTCAAACTTGGCAGCGACCTCATCGTGACCGTGCGCGGCGTCGGCT
ATATGCTGCCGCGTGACAATGCCGAAGCGCCATGA

Upstream 100 bases:

>100_bases
CCGGCCGGGGTCACTGACCGTCCCGCGGCCTCCGCGAAGCATCACGACGCCGACCGCGACGACTATTGATCCAAACCGGT
ACCGAGCGGAGATCTCATCC

Downstream 100 bases:

>100_bases
CGCGACCGCGCTCGCTCCAAGGTCGGCTGGTGTTGTTGGTGCTTGGCGCCGTCGCCGGCCTATGGCTCATCACCGCATTG
ATCACGTGGTACGACGCCCA

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRILLVEDDPLLGDGIRAGLQQQGFQVDWVRDGEAAWRELRTDAYVAAILDLGLPRMDGVDVLRKVRGAGIAVPILVLTA
RDAIPDRVRGLDLGADDYIVKPIDLHELSARLRALVRRAHGHPTEQLRARGIVLEPASRTVFCNGRAVALSTREFDLLHA
LMLNAGRVLSREQLEQCLYPWGQEVGSNSVEVHIHHLRVKLGSDLIVTVRGVGYMLPRDNAEAP

Sequences:

>Translated_224_residues
MRILLVEDDPLLGDGIRAGLQQQGFQVDWVRDGEAAWRELRTDAYVAAILDLGLPRMDGVDVLRKVRGAGIAVPILVLTA
RDAIPDRVRGLDLGADDYIVKPIDLHELSARLRALVRRAHGHPTEQLRARGIVLEPASRTVFCNGRAVALSTREFDLLHA
LMLNAGRVLSREQLEQCLYPWGQEVGSNSVEVHIHHLRVKLGSDLIVTVRGVGYMLPRDNAEAP
>Mature_224_residues
MRILLVEDDPLLGDGIRAGLQQQGFQVDWVRDGEAAWRELRTDAYVAAILDLGLPRMDGVDVLRKVRGAGIAVPILVLTA
RDAIPDRVRGLDLGADDYIVKPIDLHELSARLRALVRRAHGHPTEQLRARGIVLEPASRTVFCNGRAVALSTREFDLLHA
LMLNAGRVLSREQLEQCLYPWGQEVGSNSVEVHIHHLRVKLGSDLIVTVRGVGYMLPRDNAEAP

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=54.1666666666667, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=43.9814814814815, Blast_Score=177, Evalue=4e-46,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=38.4615384615385, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.4545454545455, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=37.1559633027523, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=36.3636363636364, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=37.3873873873874, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=36.5217391304348, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.5132743362832, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=34.2465753424658, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=28.3185840707965, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=29.004329004329, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=29.6296296296296, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=123, Percent_Identity=31.7073170731707, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24792; Mature: 24792

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDDPLLGDGIRAGLQQQGFQVDWVRDGEAAWRELRTDAYVAAILDLGLPRMDGV
CEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCH
DVLRKVRGAGIAVPILVLTARDAIPDRVRGLDLGADDYIVKPIDLHELSARLRALVRRAH
HHHHHHHCCCCEEEHEEEECCCCCHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHC
GHPTEQLRARGIVLEPASRTVFCNGRAVALSTREFDLLHALMLNAGRVLSREQLEQCLYP
CCCHHHHHHCCEEECCCCCEEEECCEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WGQEVGSNSVEVHIHHLRVKLGSDLIVTVRGVGYMLPRDNAEAP
HHHHHCCCCEEEEEEEEEEEECCCEEEEEECCEEECCCCCCCCC
>Mature Secondary Structure
MRILLVEDDPLLGDGIRAGLQQQGFQVDWVRDGEAAWRELRTDAYVAAILDLGLPRMDGV
CEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCH
DVLRKVRGAGIAVPILVLTARDAIPDRVRGLDLGADDYIVKPIDLHELSARLRALVRRAH
HHHHHHHCCCCEEEHEEEECCCCCHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHC
GHPTEQLRARGIVLEPASRTVFCNGRAVALSTREFDLLHALMLNAGRVLSREQLEQCLYP
CCCHHHHHHCCEEECCCCCEEEECCEEEEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHH
WGQEVGSNSVEVHIHHLRVKLGSDLIVTVRGVGYMLPRDNAEAP
HHHHHCCCCEEEEEEEEEEEECCCEEEEEECCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]