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The map label for this gene is pilE1 [H]

Identifier: 187927580

GI number: 187927580

Start: 514033

End: 514557

Strand: Direct

Name: pilE1 [H]

Synonym: Rpic_0480

Alternate gene names: 187927580

Gene position: 514033-514557 (Clockwise)

Preceding gene: 187927579

Following gene: 187927582

Centisome position: 13.04

GC content: 55.62

Gene sequence:

>525_bases
ATGCAGTTGCATTACCAGTACAACGGGCGACACCAGCGCGGTTTTACTCTGATTGAGCTGATGATCGTTGTTGCGATTGT
CGGTATTCTGGCGGCGATCGCCGTCCCCGCGTATCAAGATTACGTCACGCGCGCCCGCGTAAGCGAGGGGTTGGCCCTCG
CAGCATCAGCCAAGACAACTGTGGCCGAGAACGCCAGCGCTGGGGTTCCGTTCGACGAGGGTTTCGCCGCAGACACGAAA
GCCACGCGCTACGTCCAAGCGAAAGGCATCGTGATCAGTCAAAAGACTGGCGAAATTCAAATTAAATACACTGATTCGGT
AGCGAAAGACGGTGAAAATGTCTTGTTGCTCAAGCCAACAACCTATGATGAAGCCATGAGCGGGTCAAGCGCGAGCAGTG
TTCGCCCCACAGGTCCAATTCGTTGGGATTGCTATGCCAAGGGCGCCGCCGTCCGAGCAGGAACAGCCGAACTTGAAACG
AAGCCGTCATTGGCGACAAATGTTGCACCTGCGGAATGCCGGTAA

Upstream 100 bases:

>100_bases
AAAATGAGTTGTGCTTCATGTTAATAAGCAACTGATTCGTTAATCTCCTCCCACCTCATTAAATTCAATGAGGATCCATT
TTTGCATCTGGAGGAGAAAA

Downstream 100 bases:

>100_bases
TTTAAGCGCCAAATGATGAGAGCGCCGACGGCGCTCTCTGTTCTTTCTAATCAGCCACCCAATCCCCCGACTTCCCCCCT
CGCTTCTCCATCAACCGCAC

Product: pilin subfamily protein

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MQLHYQYNGRHQRGFTLIELMIVVAIVGILAAIAVPAYQDYVTRARVSEGLALAASAKTTVAENASAGVPFDEGFAADTK
ATRYVQAKGIVISQKTGEIQIKYTDSVAKDGENVLLLKPTTYDEAMSGSSASSVRPTGPIRWDCYAKGAAVRAGTAELET
KPSLATNVAPAECR

Sequences:

>Translated_174_residues
MQLHYQYNGRHQRGFTLIELMIVVAIVGILAAIAVPAYQDYVTRARVSEGLALAASAKTTVAENASAGVPFDEGFAADTK
ATRYVQAKGIVISQKTGEIQIKYTDSVAKDGENVLLLKPTTYDEAMSGSSASSVRPTGPIRWDCYAKGAAVRAGTAELET
KPSLATNVAPAECR
>Mature_174_residues
MQLHYQYNGRHQRGFTLIELMIVVAIVGILAAIAVPAYQDYVTRARVSEGLALAASAKTTVAENASAGVPFDEGFAADTK
ATRYVQAKGIVISQKTGEIQIKYTDSVAKDGENVLLLKPTTYDEAMSGSSASSVRPTGPIRWDCYAKGAAVRAGTAELET
KPSLATNVAPAECR

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 18483; Mature: 18483

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLHYQYNGRHQRGFTLIELMIVVAIVGILAAIAVPAYQDYVTRARVSEGLALAASAKTT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHH
VAENASAGVPFDEGFAADTKATRYVQAKGIVISQKTGEIQIKYTDSVAKDGENVLLLKPT
CCCCCCCCCCCCCCCCCCCCHHEEEEECCEEEECCCCEEEEEECCHHHCCCCCEEEECCC
TYDEAMSGSSASSVRPTGPIRWDCYAKGAAVRAGTAELETKPSLATNVAPAECR
CHHHHHCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure
MQLHYQYNGRHQRGFTLIELMIVVAIVGILAAIAVPAYQDYVTRARVSEGLALAASAKTT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHH
VAENASAGVPFDEGFAADTKATRYVQAKGIVISQKTGEIQIKYTDSVAKDGENVLLLKPT
CCCCCCCCCCCCCCCCCCCCHHEEEEECCEEEECCCCEEEEEECCHHHCCCCCEEEECCC
TYDEAMSGSSASSVRPTGPIRWDCYAKGAAVRAGTAELETKPSLATNVAPAECR
CHHHHHCCCCCCCCCCCCCEEEEEEECCCEEECCCCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]