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The map label for this gene is sucD [H]

Identifier: 187927575

GI number: 187927575

Start: 508839

End: 509720

Strand: Direct

Name: sucD [H]

Synonym: Rpic_0475

Alternate gene names: 187927575

Gene position: 508839-509720 (Clockwise)

Preceding gene: 187927574

Following gene: 187927576

Centisome position: 12.91

GC content: 62.59

Gene sequence:

>882_bases
ATGTCGATTCTGATCAACAAAGACACCAAGGTCATCACCCAGGGGATCACCGGTAAGACCGGCCAGTTCCACACCCGCGG
CTGCCGCGACTACGCCAACGGCAAGAACGCCTTCGTGGCAGGCGTGAACCCGAAGAAGGCCGGCGAAGACTTCGAAGGCA
TTCCCATCTACGCAACCGTCAAGGACGCCAAGGCCCAGACCGGCGCGACCGTGTCGGTGATCTACGTGCCGCCCGCTGGC
GCCGCTGATGCAATCTGGGAAGCTGTCGAAGCCGAACTGGACCTGGTGGTTTGCATCACCGAAGGCATCCCCGTGCGCGA
CATGATGATGGTCAAGGACAAGATGCGTAAGGCCGGCAGCAAGACGCTGCTGCTGGGCCCGAACTGCCCGGGCCTGATCA
CGCCGGACGAAATCAAGATCGGCATCATGCCGGGTCATATCCACCGCAAGGGCCGCATCGGCGTGGTGTCGCGCTCGGGC
ACGCTGACGTACGAAGCCGTGGGCCAGCTCACCGCGCTGGGCCTGGGCCAATCGTCGGCTGTCGGTATCGGCGGCGACCC
GATCAACGGTCTGAAGCACATCGACGTGATGAAGATGTTCAACGACGATCCGGAAACGGACGCCGTGGTCATGATCGGTG
AGATCGGCGGTCCGGACGAAGCCAACGCGGCTTACTGGATCAAGGACAACATGAAGAAGCCGGTGGTTGGCTTCATCGCT
GGCGTGACCGCGCCTCCGGGCAAGCGCATGGGCCACGCCGGCGCGCTGATCTCGGGCGGTGCCGACACCGCGCAAGCCAA
GCTCGACATCATGGAAGAATGCGGCATCAAGACCACCAAGAACCCGTCGGAAATGGCACGTCTGCTCAAGGCGATGCTGT
AA

Upstream 100 bases:

>100_bases
GCCGGCAAGTAAGCCGCCCGCTGACCCAACCATACGCGAACGCGAGTTGCGCCCGCTGCTGAGTACGTCGGCGCGGCTCG
CTGCATAAAAGGATTACAGC

Downstream 100 bases:

>100_bases
TCGATCAGGTTTGAGGTTGTGCGAGAACGGGGGCTTCGGCTCCCGTTTTTGTTTGTGCGCGACGCGGCGTGCGATCGCGG
CACGACATGTGTATAAGCAA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNAFVAGVNPKKAGEDFEGIPIYATVKDAKAQTGATVSVIYVPPAG
AADAIWEAVEAELDLVVCITEGIPVRDMMMVKDKMRKAGSKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAQAKLDIMEECGIKTTKNPSEMARLLKAML

Sequences:

>Translated_293_residues
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNAFVAGVNPKKAGEDFEGIPIYATVKDAKAQTGATVSVIYVPPAG
AADAIWEAVEAELDLVVCITEGIPVRDMMMVKDKMRKAGSKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAQAKLDIMEECGIKTTKNPSEMARLLKAML
>Mature_292_residues
SILINKDTKVITQGITGKTGQFHTRGCRDYANGKNAFVAGVNPKKAGEDFEGIPIYATVKDAKAQTGATVSVIYVPPAGA
ADAIWEAVEAELDLVVCITEGIPVRDMMMVKDKMRKAGSKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGT
LTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIAG
VTAPPGKRMGHAGALISGGADTAQAKLDIMEECGIKTTKNPSEMARLLKAML

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=55.4006968641115, Blast_Score=264, Evalue=6e-71,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=27.5590551181102, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=27.5590551181102, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=55.2901023890785, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=28.6486486486486, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=54.8611111111111, Blast_Score=298, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17553126, Length=297, Percent_Identity=52.1885521885522, Blast_Score=287, Evalue=4e-78,
Organism=Caenorhabditis elegans, GI17557344, Length=263, Percent_Identity=25.8555133079848, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=228, Percent_Identity=26.7543859649123, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=47.2972972972973, Blast_Score=256, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21356559, Length=297, Percent_Identity=50.5050505050505, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI28574296, Length=296, Percent_Identity=52.7027027027027, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI281363477, Length=231, Percent_Identity=29.4372294372294, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI281363475, Length=231, Percent_Identity=29.4372294372294, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281363473, Length=231, Percent_Identity=29.4372294372294, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30768; Mature: 30637

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNAFVAGVNPKKAGEDFEGIPIYATV
CEEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCCEEEECCCCHHCCCCCCCEEEEEEE
KDAKAQTGATVSVIYVPPAGAADAIWEAVEAELDLVVCITEGIPVRDMMMVKDKMRKAGS
ECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
CEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCEEEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEHEE
GVTAPPGKRMGHAGALISGGADTAQAKLDIMEECGIKTTKNPSEMARLLKAML
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SILINKDTKVITQGITGKTGQFHTRGCRDYANGKNAFVAGVNPKKAGEDFEGIPIYATV
EEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCCEEEECCCCHHCCCCCCCEEEEEEE
KDAKAQTGATVSVIYVPPAGAADAIWEAVEAELDLVVCITEGIPVRDMMMVKDKMRKAGS
ECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
CEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCEEEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEHEE
GVTAPPGKRMGHAGALISGGADTAQAKLDIMEECGIKTTKNPSEMARLLKAML
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA