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The map label for this gene is sucC [H]

Identifier: 187927574

GI number: 187927574

Start: 507584

End: 508750

Strand: Direct

Name: sucC [H]

Synonym: Rpic_0474

Alternate gene names: 187927574

Gene position: 507584-508750 (Clockwise)

Preceding gene: 187927573

Following gene: 187927575

Centisome position: 12.87

GC content: 62.3

Gene sequence:

>1167_bases
ATGAATATCCATGAGTACCAAGGCAAGGAAATCCTGCGCAAATACAATGTGCCGGTTCCGCGCGGCATTCCGGCCTTCTC
GGTCGACGAGGCCATCAAGGCTGCTGAAACCCTGGGCGGCCCGGTGTGGGTCGTGAAGGCGCAGATTCATGCGGGTGGCC
GTGGCAAGGGCGGTGGCGTGAAGGTTGCCAAGAGCATCGAGCAGGTCAAGGAATACGCCAGCAGCATCCTGGGCATGACG
CTGGTGACGCACCAGACCGGTCCGGAAGGCAAGCTGGTCAAGCGCCTGCTGATTGAAGAAGGCGCGGACATCAAGAAGGA
ACTGTACGTGTCGCTGGTGGTGGACCGTGTGTCGCAGCAAGTGGCGCTGATGGCCTCCAGCGAAGGCGGCATGGACATCG
AAGAAGTCGCCGAATCGCACCCGGAAAAGATCCACACGCTGTTGATCGATCCGCAAGCCGGTCTGCAAGACGCCCAGGCT
GACGACATCGCCCGCAAGATCGGCGTGCCCGACGCGAGCGTGCCGCAAGCCCGCCAAGCCCTGCAGGGCCTGTACAAGGC
ATTCTGGGAAACCGACGCTTCGCAAGCTGAAATCAACCCGCTGATCCTGACCGGCGACGGCAAGGTCATCGCGCTGGACG
CCAAGTTCAACTTCGACTCGAACGCGCTGTTCCGTCACCCGGAAATCGTGGCGTACCGCGATCTGGATGAAGAAGACCCG
GCCGAAATCGAAGCCTCGAAGTTCGACCTGGCCTACATCTCGCTCGACGGCAACATCGGCTGCCTGGTGAACGGCGCCGG
TCTGGCCATGGCCACGATGGACACCATCAAGCTGTTCGGCGGCGAGCCGGCCAACTTCCTCGACGTGGGCGGCGGTGCCA
CCACCGAGAAGGTGACCGAAGCCTTCAAGCTGATGCTGAAGAACCCGGACGTGAAGGCCATCCTGGTCAACATCTTCGGC
GGCATCATGCGTTGCGACGTGATCGCCGAAGGCGTGATCGCGGCAGCAAAGGCTGTGTCGCTGTCGGTGCCGCTGGTTGT
GCGCATGAAGGGCACCAACGAAGACCTCGGCAAGAAGATGCTGGCCGACTCGGGTCTGCCCATCATCGCCGCAGACACGA
TGGCAGAGGCCGCCGAGAAGGTCGTGGCCGCAGCCGCCGGCAAGTAA

Upstream 100 bases:

>100_bases
ACCCACCGAACTGTCGCCTGAGCCCTCGTCCTGAAGGGCACCGCGCTGTTCGCGTTTTCAATACTCATAACACTCACTCT
GCCTAGCAAAGGAAACACGC

Downstream 100 bases:

>100_bases
GCCGCCCGCTGACCCAACCATACGCGAACGCGAGTTGCGCCCGCTGCTGAGTACGTCGGCGCGGCTCGCTGCATAAAAGG
ATTACAGCATGTCGATTCTG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVDEAIKAAETLGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVKEYASSILGMT
LVTHQTGPEGKLVKRLLIEEGADIKKELYVSLVVDRVSQQVALMASSEGGMDIEEVAESHPEKIHTLLIDPQAGLQDAQA
DDIARKIGVPDASVPQARQALQGLYKAFWETDASQAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDVKAILVNIFG
GIMRCDVIAEGVIAAAKAVSLSVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMAEAAEKVVAAAAGK

Sequences:

>Translated_388_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVDEAIKAAETLGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVKEYASSILGMT
LVTHQTGPEGKLVKRLLIEEGADIKKELYVSLVVDRVSQQVALMASSEGGMDIEEVAESHPEKIHTLLIDPQAGLQDAQA
DDIARKIGVPDASVPQARQALQGLYKAFWETDASQAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDVKAILVNIFG
GIMRCDVIAEGVIAAAKAVSLSVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMAEAAEKVVAAAAGK
>Mature_388_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVDEAIKAAETLGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVKEYASSILGMT
LVTHQTGPEGKLVKRLLIEEGADIKKELYVSLVVDRVSQQVALMASSEGGMDIEEVAESHPEKIHTLLIDPQAGLQDAQA
DDIARKIGVPDASVPQARQALQGLYKAFWETDASQAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDVKAILVNIFG
GIMRCDVIAEGVIAAAKAVSLSVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMAEAAEKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=48.3290488431877, Blast_Score=354, Evalue=8e-98,
Organism=Homo sapiens, GI157779135, Length=378, Percent_Identity=46.5608465608466, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.5181058495822, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.8350515463918, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=46.5648854961832, Blast_Score=351, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=45.6185567010309, Blast_Score=328, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=47.0737913486005, Blast_Score=354, Evalue=1e-98,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=45.959595959596, Blast_Score=333, Evalue=8e-92,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=46.1734693877551, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=46.1734693877551, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=46.3104325699746, Blast_Score=328, Evalue=4e-90,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=46.3104325699746, Blast_Score=328, Evalue=4e-90,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41140; Mature: 41140

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEILRKYNVPVPRGIPAFSVDEAIKAAETLGGPVWVVKAQIHAGGRGKGGGV
CCCCHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSIEQVKEYASSILGMTLVTHQTGPEGKLVKRLLIEEGADIKKELYVSLVVDRVSQQ
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VALMASSEGGMDIEEVAESHPEKIHTLLIDPQAGLQDAQADDIARKIGVPDASVPQARQA
EEEEECCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASQAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDVKAILVNIFGGIMRCDVIAEGVIAAAKAVSLSVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCHHHHHHH
LADSGLPIIAADTMAEAAEKVVAAAAGK
HHCCCCCEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQGKEILRKYNVPVPRGIPAFSVDEAIKAAETLGGPVWVVKAQIHAGGRGKGGGV
CCCCHHCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSIEQVKEYASSILGMTLVTHQTGPEGKLVKRLLIEEGADIKKELYVSLVVDRVSQQ
HHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VALMASSEGGMDIEEVAESHPEKIHTLLIDPQAGLQDAQADDIARKIGVPDASVPQARQA
EEEEECCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASQAEINPLILTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPDVKAILVNIFGGIMRCDVIAEGVIAAAKAVSLSVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEECCCCHHHHHHH
LADSGLPIIAADTMAEAAEKVVAAAAGK
HHCCCCCEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA