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The map label for this gene is actP [H]

Identifier: 187927565

GI number: 187927565

Start: 497784

End: 499514

Strand: Direct

Name: actP [H]

Synonym: Rpic_0465

Alternate gene names: 187927565

Gene position: 497784-499514 (Clockwise)

Preceding gene: 187927564

Following gene: 187927566

Centisome position: 12.63

GC content: 63.26

Gene sequence:

>1731_bases
ATGAAGAAGATGCTTTCGATCCTGCTGGTGGCGCTACTGGCCGCTGGCGCCTGCGGGGCGGCTCTGGCTGCCGGCGGCGA
TGTCGGACAGACCGCCAAGCAGGAAACCAACACCACGGCCATCGTTCTGTTTGCTCTGTTCGTGGCCGGCACGCTGTGGA
TCACGAAGTGGGCGGCCAAGCGTACGCGGTCCGCGGCCGATTTCTACACGGCGGGCGGCGGCATCACCGGCTTCCAGAAT
GGCCTGGCCATTTCGGGCGACTACATGTCGGCAGCGTCCTTCCTCGGTATTTCCGCGGCCGTGATGACCTCCGGCTACGA
CGGCCTGATCTACTCCATCGGCTTTCTGGTCGGCTGGCCGATCATCACGTTCCTGATGGCCGAGCGGCTGCGCAACCTTG
GCAAGTTCACCTTTGCAGACGTGGCAGGCTACCGGTTCGAGCAAGGCCCGATCCGCAGCTTTGCCGCGGTTGGCACGCTG
GTGGTGGTGGCGTTCTATCTGATCGCTCAGATGGTGGGTGCAGGCCAGCTCATCAAACTGCTGTTCGGGCTGGATTACTG
GATCGCGGTGGTCATTGTCGGCGCGTTGATGATGGTCTACGTGCTGTTCGGCGGCATGACCGCAACCACCTGGGTGCAGA
TCATCAAGGCGTGCATGCTGCTGGCCGGCGTGACGTTCATGGCCATCATGGTGCTGGCGCAGTACGGTTTCAGTCTGGAG
GCGTTGTTCGCCAAGGCTGTGCAGGTCAAGACCGCCATTGCAGCCAATGCCGGCAAATCGCCCGATGAGGCCGCCAAGAT
CGGTCTGTCGGTGATGGCGCCGGGTGGCTTCATCAAGGACCCGATCTCGGCCATCTCGTTCGGCATGGCGCTGATGTTCG
GCACCGCCGGTCTGCCGCACATCCTGATGCGTTTCTTCACGGTCCCGGATGCCAAGGAGGCGCGCAAATCGGTCTTCTGG
GCGACCACCTGGATCGGCTACTTCTACATCCTGATCTTCATCATCGGCTTTGGTGCGATCACGCTGGTGTTGACGAACCC
CGAACTGTCCGACGTGGCCAAGGGTGTCATCAAGGGCGGCGCGGGCACGGCCAACATGGCTGCGGTGCTGGTGGCCAAGA
CGGTGGGCGGCGATGTGTTCTACGGCTTCATCTCGGCCGTGGCGTTTGCCACGATTCTGGCGGTGGTGGCAGGGCTCACG
CTGTCGGGTGCATCGGCGGTGTCGCATGATCTTTACGCCACGGTCTTCAAGCACGGCAAGGCCAACAGCGCCGACGAGCT
GAAGGTCTCGCGCATCACCACGCTGGTGCTGGGCGTGATCGCTGTGCTGCTGGGCATCGCTTTCGAGAAGCAGAACATCG
CGTTCATGGTGTCGCTGGCGTTTGCGGTGGCGGCATCGGCCAACTTTCCGGTGTTGTTCCTCTCGATGCTGTGGAAGGGC
TGTACCACGCGTGGTGCGGTTATCGGCGGGTTCCTGGGGCTGATCTCGTCGGTGGGTCTGACGATCGTTTCGCCGTCGGT
GTGGGAGGCCACGCTCGGCTATCCGAAGGGCTCGGCGTGGTTCCCGTACACGTCGCCCGCGCTGTTCTCGATGACGATCG
GCTTCGTGGGCGTGTGGCTGTTCTCGGTGCTGGACAGCAGCGTTCGCGCCAAGAACGAGAAGGCGTCGTTTGCCGCGCAG
CAGGTCCGCTCGGAAACGGGCCTCGGTGCGGCTGGCGCATCGGGCCACTGA

Upstream 100 bases:

>100_bases
CGGTCATCATCTTCACCGTCGTCATTACCGGCATCTACGTGCGCCGCGCCAACAGCGAATACGATCAACTGACGCAGGAC
ATCCTGAAGGACGTCGCCAA

Downstream 100 bases:

>100_bases
TCGGCCACTGGCCACGCTGACTGGAGGCGGGTGACGCATTGCATCGCCCGCCTTCAAGGCAACCATGCCCAGCGCTTTCA
ACTTCGCCGTCTGGCCATTC

Product: sodium solute transporter superfamily protein

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MKKMLSILLVALLAAGACGAALAAGGDVGQTAKQETNTTAIVLFALFVAGTLWITKWAAKRTRSAADFYTAGGGITGFQN
GLAISGDYMSAASFLGISAAVMTSGYDGLIYSIGFLVGWPIITFLMAERLRNLGKFTFADVAGYRFEQGPIRSFAAVGTL
VVVAFYLIAQMVGAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACMLLAGVTFMAIMVLAQYGFSLE
ALFAKAVQVKTAIAANAGKSPDEAAKIGLSVMAPGGFIKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKEARKSVFW
ATTWIGYFYILIFIIGFGAITLVLTNPELSDVAKGVIKGGAGTANMAAVLVAKTVGGDVFYGFISAVAFATILAVVAGLT
LSGASAVSHDLYATVFKHGKANSADELKVSRITTLVLGVIAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFLSMLWKG
CTTRGAVIGGFLGLISSVGLTIVSPSVWEATLGYPKGSAWFPYTSPALFSMTIGFVGVWLFSVLDSSVRAKNEKASFAAQ
QVRSETGLGAAGASGH

Sequences:

>Translated_576_residues
MKKMLSILLVALLAAGACGAALAAGGDVGQTAKQETNTTAIVLFALFVAGTLWITKWAAKRTRSAADFYTAGGGITGFQN
GLAISGDYMSAASFLGISAAVMTSGYDGLIYSIGFLVGWPIITFLMAERLRNLGKFTFADVAGYRFEQGPIRSFAAVGTL
VVVAFYLIAQMVGAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACMLLAGVTFMAIMVLAQYGFSLE
ALFAKAVQVKTAIAANAGKSPDEAAKIGLSVMAPGGFIKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKEARKSVFW
ATTWIGYFYILIFIIGFGAITLVLTNPELSDVAKGVIKGGAGTANMAAVLVAKTVGGDVFYGFISAVAFATILAVVAGLT
LSGASAVSHDLYATVFKHGKANSADELKVSRITTLVLGVIAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFLSMLWKG
CTTRGAVIGGFLGLISSVGLTIVSPSVWEATLGYPKGSAWFPYTSPALFSMTIGFVGVWLFSVLDSSVRAKNEKASFAAQ
QVRSETGLGAAGASGH
>Mature_576_residues
MKKMLSILLVALLAAGACGAALAAGGDVGQTAKQETNTTAIVLFALFVAGTLWITKWAAKRTRSAADFYTAGGGITGFQN
GLAISGDYMSAASFLGISAAVMTSGYDGLIYSIGFLVGWPIITFLMAERLRNLGKFTFADVAGYRFEQGPIRSFAAVGTL
VVVAFYLIAQMVGAGQLIKLLFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACMLLAGVTFMAIMVLAQYGFSLE
ALFAKAVQVKTAIAANAGKSPDEAAKIGLSVMAPGGFIKDPISAISFGMALMFGTAGLPHILMRFFTVPDAKEARKSVFW
ATTWIGYFYILIFIIGFGAITLVLTNPELSDVAKGVIKGGAGTANMAAVLVAKTVGGDVFYGFISAVAFATILAVVAGLT
LSGASAVSHDLYATVFKHGKANSADELKVSRITTLVLGVIAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFLSMLWKG
CTTRGAVIGGFLGLISSVGLTIVSPSVWEATLGYPKGSAWFPYTSPALFSMTIGFVGVWLFSVLDSSVRAKNEKASFAAQ
QVRSETGLGAAGASGH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=440, Percent_Identity=23.4090909090909, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1790503, Length=576, Percent_Identity=62.8472222222222, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=477, Percent_Identity=24.9475890985325, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 60095; Mature: 60095

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMLSILLVALLAAGACGAALAAGGDVGQTAKQETNTTAIVLFALFVAGTLWITKWAAK
CHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RTRSAADFYTAGGGITGFQNGLAISGDYMSAASFLGISAAVMTSGYDGLIYSIGFLVGWP
HHCCHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
IITFLMAERLRNLGKFTFADVAGYRFEQGPIRSFAAVGTLVVVAFYLIAQMVGAGQLIKL
HHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
LFGLDYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACMLLAGVTFMAIMVLAQYGFSLE
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ALFAKAVQVKTAIAANAGKSPDEAAKIGLSVMAPGGFIKDPISAISFGMALMFGTAGLPH
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHCCCHHH
ILMRFFTVPDAKEARKSVFWATTWIGYFYILIFIIGFGAITLVLTNPELSDVAKGVIKGG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCCC
AGTANMAAVLVAKTVGGDVFYGFISAVAFATILAVVAGLTLSGASAVSHDLYATVFKHGK
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
ANSADELKVSRITTLVLGVIAVLLGIAFEKQNIAFMVSLAFAVAASANFPVLFLSMLWKG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHC
CTTRGAVIGGFLGLISSVGLTIVSPSVWEATLGYPKGSAWFPYTSPALFSMTIGFVGVWL
CCCCHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
FSVLDSSVRAKNEKASFAAQQVRSETGLGAAGASGH
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA